10        20        30        40        50        60        70        80        90       100       110       120
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
D_rerio_ENSDARP00000065554                IYMRTHTQGMTIKPFSLLAIPFPISLSQM----------------------------------------------EILQN-SAFLRGLCRTSG-PADL-QYDNSSELFRISTYAKFPTTA
T_rubripes_ENSTRUP00000043752             --LLSPDPPLGGPTFTLILLCFHTKMETL----------------------------------------------VQLKN-NPFLMGLCRNCP-PPDL-QYDNSSELYRISTFARFPT-S
T_nigroviridis_ENSTNIP00000012883         --L----PALFEGLLPFILLCFDTKMETL----------------------------------------------VQLKN-NPFLMGLCRNCP-PPDL-QYDNSSELYRISTFARFPS-S
O_latipes_ENSORLP00000006992              ----------------------------L----------------------------------------------VQLKN-SKFLMGLCRNGP-PSDL-QYDNSSELFRFSTFARFPT-S
G_aculeatus_ENSGACP00000027283            ------------------------------------------------------------------------------KN-NPFLMGLCRNGP-PPDL-QYDNSSELFRISTFARFPA-S
T_guttata_ENSTGUP00000013125              ----------------------------L----------------------------------------------NTVED-SPFLTSIMRQSALCDEL-KYDLSCELYRMSTFSTFPMNT
O_anatinus_ENSOANP00000016616             -----VHKTTSRGETRPVSPATPTEYFVM----------------------------------------------NVVAN-SMFLSNLMNGNS-GYEL-KYDFSCELFRMSTYSTFPTNV
G_gallus_ENSGALP00000035646               ----------------------------M----------------------------------------------NIMDS-SPLLASVMKQNAHCGEL-KYDLSCELYRMSTFSTFPVNV
E_caballus_ENSECAP00000000598             -----------------------------------------------------------------------------MED-STILSSWTVGNK--QKM-KYDFSCELYRMSTYSTFPTGV
M_mulatta_ENSMMUP00000004536              ----------MHKTASQRLFPGPSYQNIK----------------------------------------------SIMED-STILSDWTNSNK--QKM-KYDFSCELYRMSTYSTFPTGV
H_sapiens_ENSP00000227758                 ----------MHKTASQRLFPGPSYQNIK----------------------------------------------SIMED-STILSDWTNSNK--QKM-KYDFSCELYRMSTYSTFPAGV
P_pygmaeus_ENSPPYP00000004357             ----------MHKTASQRLFPGPSYQN-K----------------------------------------------SIMED-STILSDWTNSNK--QKM-KYDFSCELYRMSTYSTFPAGV
P_troglodytes_ENSPTRP00000007251          ----------MHKTASQRLFPGPSYQNIK----------------------------------------------SIMED-STILSDWTNSNK--QKM-KYDFSCELYRMSTYSTFPAGV
C_familiaris_ENSCAFP00000022277           ----------MHKTTSQRLVPG-SYQRIK----------------------------------------------RTMED-STILRNQTIGNK--QKI-KYDFSCELYRMSTYSTFPAGV
E_caballus_ENSECAP00000010270             ----------------------------M----------------------------------------------NIVEN-SVFLSNLMKSAN-MFEL-KYDFSCELYRISTYSTFPPGV
M_domestica_ENSMODP00000000728            -----THKTTSQRKT---CPLLFPKYSIM----------------------------------------------SVVED-GVLLSHLMSSDT--HEM-KYDLSCELYRMSTYSAFPVNV
A_carolinensis_ENSACAP00000012475         ----------------------------L----------------------------------------------IIMNTFDTFAAKLKNVPD-VGQL-KYDLSCELFRMSTFSTFPLHV
C_familiaris_ENSCAFP00000022282           ----------------------------M----------------------------------------------NIVQN-SIFLSNLLRSSP-VFEL-KYDHSCELYRMSTYSTFPAGV
P_troglodytes_ENSPTRP00000007250          ----------------------------M----------------------------------------------NIVEN-SIFLSNLMKSAN-TFEL-KYDLSCELYRMSTYSTFPAGV
M_mulatta_ENSMMUP00000004533              ----------------------------M----------------------------------------------NIVEN-SIFLSNLMKSAN-TFEL-KYDLSCELYRMSTYSAFPAGV
H_sapiens_ENSP00000376897                 ----------------------------M----------------------------------------------NIVEN-SIFLSNLMKSAN-TFEL-KYDLSCELYRMSTYSTFPAGV
M_musculus_ENSMUSP00000091422             ----------MDKTVSQRLGQGTLHQKLK----------------------------------------------RIMEK-STILSNWTKESE--EKM-KFDFSCELYRMSTYSAFPRGV
P_pygmaeus_ENSPPYP00000004355             ----------------------------M----------------------------------------------NIVEN-SIFLSNLMKSAN-TFEL-KYDLSCELYRMSTYSTFPAGV
R_norvegicus_ENSRNOP00000007702           ----------------------------M----------------------------------------------NMVQG-SAFLAKLMKSAD-TFEL-KYDFSCELYRLSTYSTFPAGV
R_norvegicus_ENSRNOP00000014560           ----------------------------------------------------------------------------IMEN-STVLSNWTKENK--EKM-KYDFSCELYRMSTYSAFPRGV
X_tropicalis_ENSXETP00000048002           --------------------------MAN----------------------------------------------EILDR-RPDLAKRLKSNPSMCKI-TLEFSCELYRLSTFSTFPSNT
M_musculus_ENSMUSP00000013949             ----------------------------M----------------------------------------------NMVQD-SAFLAKLMKSAD-TFEL-KYDFSCELYRLSTYSAFPRGV
B_taurus_ENSBTAP00000034604               ----------------------------M----------------------------------------------NIVEN-SVFLSNLMKSAN-MFEL-KYDFSCELYRMSTYSTFPAGV
O_cuniculus_ENSOCUP00000011948            -----------HKTTSPRVVPG-TVYRTQ----------------------------------------------NMMED-STILXXXXXXXX--XXX-XXXXXXXXXXXXXXXXSPNGV
M_domestica_ENSMODP00000000705            ----------------------------M----------------------------------------------NLVEN-IMFLSNMNISNL--YEL-KYDFSCELYRISTYSAFPVNV
O_cuniculus_ENSOCUP00000008710            ----------------------------M----------------------------------------------NIVEN-SIFLANLMKSAN-TFEL-KYDFSCELYRMSTYSTFPAGV
D_rerio_ENSDARP00000075338                ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000014265            -----MHKTASQRVV------PGTSYRIK----------------------------------------------SMMED-STISSNTNDQNQ---KM-KYDFSYKI-RVPTYSGLPIRV
G_gorilla_ENSGGOP00000008137              ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000046955               ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000110746             --------------------------MTF----------------------------------------------NSFEGTRTFVLA-------DTNK-DEEFVEEFNRLKTFANFPSSS
R_norvegicus_ENSRNOP00000009358           --------------------------MTF----------------------------------------------NSFEGSRTVVPA-------DTNK-DEEFVEEFNRLKTFANFPSSS
C_familiaris_ENSCAFP00000034255           --------------------------MTF----------------------------------------------NSFEGAKTCVPA-------GINK-DEEFVEEFNRLKTFANFPSSS
P_pygmaeus_ENSPPYP00000023167             --------------------------MTF----------------------------------------------NSFEGSKTCVPA-------DINK-EEEFVEEFNRLKTFANFPSGS
B_taurus_ENSBTAP00000053449               --------------------------MTF----------------------------------------------NSFEGSKTCVPA-------DIDK-DEEFVEEFNRLKTFANFPSSS
C_intestinalis_ENSCINP00000000045         --------------------------------------------------------------------------------------------------------MESYRLSTFMKYPQDT
E_caballus_ENSECAP00000017630             --------------------------MTF----------------------------------------------NSFEGSKTCVPA-------DIDK-DEEFVEEFNRLKTFANFPSSS
H_sapiens_ENSP00000360242                 --------------------------MTF----------------------------------------------NSFEGSKTCVPA-------DINK-EEEFVEEFNRLKTFANFPSGS
P_troglodytes_ENSPTRP00000038304          --------------------------MTF----------------------------------------------NSFEGSKTCVPA-------DINK-EEEFVEEFNRLKTFANFPSGS
O_cuniculus_ENSOCUP00000008505            --------------------------MTF----------------------------------------------NSFEGSKTCVPA-------DINK-DEEFVEEFNRLKTFANFPSSS
G_gallus_ENSGALP00000038337               --------------------------MTC----------------------------------------------NGPDSSESGATP-------ATDG-DQEWTQEHYRLGTFVEFPHDC
M_domestica_ENSMODP00000018715            --------------------------MTF----------------------------------------------KSFEDSKTCVPP-------DINK-DEDFVEEFNRLKTFANFPSSS
T_guttata_ENSTGUP00000003825              --------------------------AD-------------------------------------------------------------------TDG-AREWAQERERQGTFVGFPQGC
C_intestinalis_ENSCINP00000005161         -----------------------------------------------------------------------------------------------------DSAMESYRLSTFMKYPQDT
T_nigroviridis_ENSTNIP00000006583         ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000035327           ------------------------------------------------------------------------LAEFVLKEEMTCQCPKMSDGAYDMDV-DQNYFEEEVRLASFANFPSSY
G_aculeatus_ENSGACP00000003419            ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000011958             ------------------------------------------------------------------------------------------------------------------------
G_gorilla_ENSGGOP00000005705              ----------------------------M----------------------------------------------NIVEN-SIFLSNLMKSAN-TFEL-KYDLSCELYRMSTYSTFPAGV
C_intestinalis_ENSCINP00000009820         -----------------------------------------------------------------------------------------------------DAAMESYRLSTFMKYPQDT
X_tropicalis_ENSXETP00000030727           ----------------------------N----------------------------------------------EILDR-RPDLAKRLKSNPSMCKI-TLEFSCELYRLSTFSSFPSNT
O_latipes_ENSORLP00000010149              ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000029187           ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000010298             ---------------------------------------------------------------------MNPFDNMQLKKEITMEDQQHDSGTLETDS-AEDFSLITSRLESFRGSNLVQ
O_anatinus_ENSOANP00000006435             --------------------------MTC----------------------------------------------NSPEELRTSNPS-------EVNK-DEEFAEEHNRLRTFANFPSTS
D_melanogaster_FBpp0086432                -------------------------------------------------------------------------------------------------MTELGMELESVRLATFGEWPLNA
G_gorilla_ENSGGOP00000008442              --------------------------MTF----------------------------------------------NSFEGSKTCVPA-------DINK-EEEFVEEFNRLKTFANFPSGS
A_carolinensis_ENSACAP00000011315         ---------------------------------------------------------------------------------------------------------ELSRQQTFASFPSDC
A_aegypti_AAEL006633-PA                   ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000018867         -----------------------------------------------------------------------------------MEDQRHDNSNLETDS-AEDFSLIKSRLESFRGSSLVQ
D_rerio_ENSDARP00000013586                -------------------------------------------------------------------------FPPQRNLVTTNMAHSTHNGELESDNVAADWSVMKNRVNSFQRFPYSE
G_aculeatus_ENSGACP00000024474            -------------------------------------------------------------------------VPPSSILSSSIMCALRQDNQLESDH-MADFSEINNRLDSFRGSSLAQ
O_latipes_ENSORLP00000012199              ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002256         --------------------------------------------------------------------------------------------------------MESYRLSTFMKYPQDT
G_gallus_ENSGALP00000009239               ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000007779              ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000021022            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000000487         --------------------------------------------------------------------------------------------------------M---------------
H_sapiens_ENSP00000321377                 ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000019640          ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000000510         --------------------------------------------------------------------------------------------------------M---------------
C_intestinalis_ENSCINP00000021651         --------------------------MLV----------------------------------------------DSFCSNLKYQTMFHNIDRVSQHAAAMDYSSKSNRIQSLENFP-SA
G_gorilla_ENSGGOP00000007398              ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000000466         ------------------------------------------------------------------MELANNLFSDIETDGMKVNTTSEPSDKRCVYITPGQKEREDYRITTFNKFPSNK
X_tropicalis_ENSXETP00000016315           ---------------------------------------------------------------------------------------------------------------------KHF
X_tropicalis_ENSXETP00000016312           ----------------------------------------------------------------------------------------YSGSQNPGEKPLGDMNDEYSRLETYRGHSQYF
M_musculus_ENSMUSP00000112867             ----------------------------------------------MAEHGESSEDRISEIDYEFLAELSARFGMNLVQLAKSQEEEDHKERMKMKKGFNSQMRSEAKRLKTFESYDTFR
G_gorilla_ENSGGOP00000008152              ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000058611             ----------------------------------------------MAEHGESSEDRISEIDYEFLPELSALLGVDAFQVAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFR
C_intestinalis_ENSCINP00000020067         ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000022142             ----------------------------------------------MAEHGESSEDRISEIDYEFLPELSALLGVDAVQLAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFR
X_tropicalis_ENSXETP00000057704           ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000217169                 ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000023641          ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000034890           ---------------------------------------------------------------------------------------------------------------------KHF
B_taurus_ENSBTAP00000004317               ----------------------------------------------MATQEKAPEERISQFDYALLPEMSAFLGVNALQFVKEIEEKEHRDREKMQKGFNSQMRSEAKRLKTFVTYNTFR
M_mulatta_ENSMMUP00000012096              ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000048273          ----------------------------------------------MATQQKASDERISQFDHNLLPELSALLGLDAGQLAKELEEKEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYS
M_musculus_ENSMUSP00000113890             ----------------------------------------------MAAQGEAVEEIICEFDDDLVSELSTLLRVDALSVLKRQQEEDHKTRMKMKKGFNSQMRSEAKRLKTFETYDKFR
R_norvegicus_ENSRNOP00000024483           ----------------------------------------------MAEHGEASEDQVSEFDGECLPELSALLGVDAVQLVKSQEEEENKERMKMKKGFNAQMRSEAKRLKTFVTYDAFK
H_sapiens_ENSP00000194097                 ----------------------------------------------MATQQKASDERISQFDHNLLPELSALLGLDAVQLAKELEEEEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYS
C_intestinalis_ENSCINP00000010449         ---------------------------------------------------------------MQARMMDIRCDGLRVVHNDGRLVPSATNSERELYTRPGDPYYESYRLATFTNYP-NQ
M_musculus_ENSMUSP00000104503             ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000017359             ----------------------------------------------MATQQKASDERISQFDHDLLPELSALLGLDAVQFVKEIEEEEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYS
P_pygmaeus_ENSPPYP00000012543             ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000017749             ------------------------------------------------------------------------------------------------------------------------
D_melanogaster_FBpp0075254                ------------------------------------------------------------------------------------------------------------MASVVADLPSYG
A_aegypti_AAEL009074-PA                   ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000018803           ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000005440         ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000002314             ----------------------------------------------MATEEKAPAGRDSRFDHALLQELSALLGIDAVQYAKEMEEEEQREREKMQQGFNSRMRSEAKRLKTFATYEAYS
C_intestinalis_ENSCINP00000011648         ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007293-PA                   ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007291-PA                   ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007292-PA                   ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000002871            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002312         ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000008701         MKQRHKYLHNTRKSTAPFNNQINGNAKDKRNYEKKSLKSTLGSKGLHELCLFETFNPEVCKIHPEIKGKSYKSGGKKLRESANTDVQSDGTPAANDDNIAPTPERASEMVFRLLSFKERS
A_gambiae_AGAP011326-PA                   ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000000543            ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000002056             ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000264198                 ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000009065              ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000013139             ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000000497          ------------------------------------------------------------------------------------------------------------------------

                                                  130       140       150       160       170       180       190       200       210       220       230       240
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
D_rerio_ENSDARP00000065554                AVT-ERSLARAGFYYTGLGDRVQCFRCNVTADNWQSGDCPAERHKQLSPNCSFIQSLPAT--ANLLSSSHS-------------------------AFSPLRNVAVLQLSAPATAAPSTT
T_rubripes_ENSTRUP00000043752             GVT-ERSLARAGWFYTGVGDRVQCFKCNVTAEGWQAGDCPTEKHRQLSPSCSFIQSLPST--SNLLSSSHS-------------------------AFSPLRIAPAIPLSG---AGPAVP
T_nigroviridis_ENSTNIP00000012883         GVT-ERSLARAGWFYTGVGDRVQCFKCNVTAEGWQAGDCPTEKHRQLSPSCTFIQSLPST--SNLLSSSHS-------------------------AFSPLRIAPAIPLSG---AGPAVP
O_latipes_ENSORLP00000006992              VVT-ERSLARAGWFYTGVGDRVQCFRCNVTAEGWLAGDCPTEKHRQLSPTCPFIQSLPST--TNLLSSSHS-------------------------AFSPLRIAQAMPVSSERRQGPAAS
G_aculeatus_ENSGACP00000027283            GVT-ERSLARAGWFYIGVGDRVQCFRCNVTAEGWQAGDCPTEKHRQLSPTCSFIQSLPST--TNLLSSSHS-------------------------AFSPLRIAPAV-------------
T_guttata_ENSTGUP00000013125              PVS-ERSLARAGFYYTGVQDKVKCFSCGLTLDNWQPGDNAMEKHKQLYPRCSFVQRMLSD--NNVGLSSRS-------------------------AFSPSIANS---------LPPSLH
O_anatinus_ENSOANP00000016616             PVS-ERSLARAGFYYTGASDKVKCFSCGLMLDNWKPGDSAIEKHKQLYPSCSFIQNLLQT--HNPGASSYS-------------------------AFCPPPLGS------------LSP
G_gallus_ENSGALP00000035646               PVS-ERRLARAGFYYTGVQDKVKCFSCGLVLDNWQPGDNAMEKHKQVYPSCSFVQNMLSL--NNLGLSTHS-------------------------AFSPLVASN---------LSPSLR
E_caballus_ENSECAP00000000598             PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDNPIEKHKQLYPSCSFIQNLVSV--TSLESTSKN-------------------------TSSPMRNSF---------------
M_mulatta_ENSMMUP00000004536              PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIEKHKQLYPSCSFIQNLVS---ATLGSTSKN-------------------------T-SPMRNSF---------------
H_sapiens_ENSP00000227758                 PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVS---ASLGSTSKN-------------------------T-SPMRNSF---------------
P_pygmaeus_ENSPPYP00000004357             PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVS---ASLGSTSKN-------------------------T-SPMRNSF---------------
P_troglodytes_ENSPTRP00000007251          PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVS---ASLGSTSKN-------------------------T-SPMRNSF---------------
C_familiaris_ENSCAFP00000022277           PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKPGDNPVEKHKQLYPSCSFIHSLVSL--TSRDSTSKN-------------------------I-SAMRNSF---------------
E_caballus_ENSECAP00000010270             PVS-ERSLARAGFYYTGINDRVKCFCCGLMLDNWKQGDNPTEKHKKLYPSCSFVQNLNSV--NISGATSQL-------------------------AFSSSVTNS---------------
M_domestica_ENSMODP00000000728            PIS-ERSLARAGFYYTGVNDRVKCFCCGLMLDNWKQGDNAIDKHKQLYPSCAFIQNLISV--N--LGSSQS-------------------------TFSSSVNNA---------------
A_carolinensis_ENSACAP00000012475         PVS-ERSLARAGFYYTGVKDKVKCYSCGLMLDNWKKGDNPLDKHKQLYPSCSVVQNLTSL--NNLGSSFYS-------------------------AFSPPSLSV---------GHSSSH
C_familiaris_ENSCAFP00000022282           PVS-ERSLARAGFYYTGAKDRVRCFCCGLMLDNWKAGDSPTGKHRNLYPSCSFIQNLSAV--STVGAASQP-------------------------PAPLSEARS---------------
P_troglodytes_ENSPTRP00000007250          PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPIEKHKKLYPSCRFVQSLNSV--NNLEATSQP-------------------------TFPSSVTNS---------------
M_mulatta_ENSMMUP00000004533              PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPVEKHKKLYPSCRFVQSLNSV--NNSEATSQP-------------------------AFPSSVTNS---------------
H_sapiens_ENSP00000376897                 PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSV--NNLEATSQP-------------------------TFPSSVTNS---------------
M_musculus_ENSMUSP00000091422             PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPVEKHRQFYPSCSFVQTLLS---ASLQSPSKN-------------------------M-SPVKSRF---------------
P_pygmaeus_ENSPPYP00000004355             PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPIEKHKKLYPSCRFVQSLNSV--NNLEATSQP-------------------------TFPSSVTNS---------------
R_norvegicus_ENSRNOP00000007702           PVS-ERSLARAGFYYTGVNDKVKCFSCGLMLDNWKQGDSPIEKHRKLYPSCSFVQTLNPA--NSLEASPQP-------------------------PLPSTATST---------------
R_norvegicus_ENSRNOP00000014560           PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPTEKHRQFYPSCSFVQTLLS---GGLQSAAKN-------------------------T-SPAKSRF---------------
X_tropicalis_ENSXETP00000048002           HVS-ERNLAKAGFYYTGQDDKVKCFTCGLMLDNWKKGDNAFEKHKKLYPSCSFIQNVPSV---NLGASLYS-------------------------AFSPPASNS---------TP----
M_musculus_ENSMUSP00000013949             PVS-ERSLARAGFYYTGANDKVKCFCCGLMLDNWKQGDSPMEKHRKLYPSCNFVQTLNPA--NSLEASPRP-------------------------SLPSTAMST---------------
B_taurus_ENSBTAP00000034604               PVS-ERSLARAGFYYTGVKDKVKCFCCGLMLDNWKQGDNPIEKHKKLYPSCSFVQNLNSI--NVSGASSQP-------------------------TFHYSLTNS---------------
O_cuniculus_ENSOCUP00000011948            PVS-ERSLARAGFYYTRVNDKVKCFCCGLMLDNWKQGDNPIEKHKQLYPSCSFIQNLVS---ASLDSTIKN-------------------------T-SPVRSSF---------------
M_domestica_ENSMODP00000000705            PVS-ERSLARAGFYYTGVNDRVKCFCCGLMLDNWKQGDNAIDKHKQLFPSCAFIQNLTSV--NNLESNSQS-------------------------ALSSSLNSA---------------
O_cuniculus_ENSOCUP00000008710            PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDKPIEKHRKLYPSCSFVQSLNSV--NNWEANSRS-------------------------TFPSSVTNS---------------
D_rerio_ENSDARP00000075338                ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000014265            PLS-EWSLAPAGLYYIGMN-KVKCFCCDLMLDNWKQEYNLIEKHKQLYPSCSFSQNLISV---SLESPLRS-------------------------SF----------------------
G_gorilla_ENSGGOP00000008137              -----------------------------------------------------------------------------------------------------RNSF---------------
B_taurus_ENSBTAP00000046955               ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000110746             PVS-ASTLARAGFLYTGEGDTVQCFSCHAAIDRWQYGDSAVGRHRRISPNCRFINGFYFENGA-AQSTNPG-------------------------IQNGQY-KS---------------
R_norvegicus_ENSRNOP00000009358           PVS-ASTLARAGFLYTGEGDTVQCFSCHAAVDRWQYGDSAVGRHRRISPNCRFINGFYFENGA-TQSTSPG-------------------------IQNGQY-KS---------------
C_familiaris_ENSCAFP00000034255           PVS-ASTLARAGFLYTGEGDTVRCFSCHASIDRWQYGDSAVGRHRKVSPNCRFINGFYFENTA-AQPTNPG-------------------------IQNGQY-NA---------------
P_pygmaeus_ENSPPYP00000023167             PVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSA-TQSTNSG-------------------------IQNGQY-KV---------------
B_taurus_ENSBTAP00000053449               PVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAIGRHRRVSPNCRFINGFYFENNA-AQPTYSG-------------------------VQNGQY-KA---------------
C_intestinalis_ENSCINP00000000045         PVN-PRHLAAAGFHYTGYKDRVKCFCCGLCVESWCVGDD-VKSPRWHRSNCEFILGQDCG---NQPIGSQN-------------------------ISVQQTARPV----PAGMIMKS--
E_caballus_ENSECAP00000017630             PVS-ASTLARAGFLYTGEGDTVQCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYFENNA-AQPTNPG-------------------------VQNGQY-KV---------------
H_sapiens_ENSP00000360242                 PVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSA-TQSTNSG-------------------------IQNGQY-KV---------------
P_troglodytes_ENSPTRP00000038304          PVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSA-TQSTNSG-------------------------IQNGQY-KV---------------
O_cuniculus_ENSOCUP00000008505            PVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYFENSA-AQSTNPG-------------------------VQNGQY-KG---------------
G_gallus_ENSGALP00000038337               PVS-ASALARAGFVYTGEGDKVKCFSCHVTVEGWEPGDSAIDRHKNLSPDCRFITGSAFLENN-V---HPL-------------------------VQSHQH-RT---------------
M_domestica_ENSMODP00000018715            PIS-ASTLARAGFLYTGEGDTVKCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYFEKNA-TRFPNPI-------------------------IQNCQY-RV---------------
T_guttata_ENSTGUP00000003825              PVS-VLALAQAGFVYTGEGDKVKCFSCNTTIEGWVPGDSALERHKKLAPTCKFITESAFLKSD-M---DPV-------------------------AQNYQN-RT---------------
C_intestinalis_ENSCINP00000005161         PVN-PRHLATAGLYFTGYKDRVKCFCCGLATEQWQFGDD-EKSPRWHRSNCEFIQGHDCG---NIPIGLHC-------------------------VVKYKLLMEL----TIPIFLGSWG
T_nigroviridis_ENSTNIP00000006583         ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000035327           PVS-APALARAGFYYTGDGDRVKCFSCLAMVEGWQHGDTAIGKHRKISPNCKFINGFNNLRSDCILTQVPV-------------------------------------------------
G_aculeatus_ENSGACP00000003419            ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000011958             ------------------------------------------------------------------------------------------------------------------------
G_gorilla_ENSGGOP00000005705              PVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPIEKHKKLYPSCRFVQSLNSV--NNLEATSQP-------------------------TFPSSVTNS---------------
C_intestinalis_ENSCINP00000009820         PVN-PRHLAAAGFHYTGYKDRVKCFCCGLCVENWVSGDE-IKSKKWHRNNCELVNGNGSG---NQPIAGDD-------------------------F--KSTISPLCECKALSMVLKT--
X_tropicalis_ENSXETP00000030727           HVS-ERNLAKAGFYYTGQDDKVKCFTCGLMLDNWKKGDNAFEKHKKLYPSCSFIQNVPSV---NLGASLYS-------------------------AFSPPASNS---------TP----
O_latipes_ENSORLP00000010149              -VS-PLQLAEAGFLFTGVSDRVRCFSCQKTVENWSQEDQPVDRHIQVSPSCTFLRCTHFNRFK---------------------------------------------------------
X_tropicalis_ENSXETP00000029187           ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000010298             LVP-AERLARAGFHFIGPSDRVRCFSCHKTVENWCTGDRPVERHKEVSPFCKFLSCIYRTSSN---------------------------------------------------------
O_anatinus_ENSOANP00000006435             PVS-SSTLARAGFLYTGEEDVVRCFSCHVAVDRWQYGDSAIGRHRKISPNCRFVNGCHFKNCA-LPLANAS-------------------------LQNGELGQV---------------
D_melanogaster_FBpp0086432                PVS-AEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRRSSPICSMVLAPNHCGNV---------------------------------------------------------
G_gorilla_ENSGGOP00000008442              PVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSA-TQSTNSG-------------------------IQNGQY-KV---------------
A_carolinensis_ENSACAP00000011315         PVS-SAALAQAGFFYTGERDQVKCFSCHTMVEGWQEGDSAIERHRTIFPECRFINDIDIGRNNTYS------------------------------LLNCQHAS----------------
A_aegypti_AAEL006633-PA                   ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000018867         RVP-AERLARAGFYLVGPSDRVRCFSCQKTVENWSREDRPVERHKEVSPVCQFLSCIYGTRPH---------------------------------------------------------
D_rerio_ENSDARP00000013586                DIS-AQRLARAGFYFTGEGDRVQCFSCSATVQNWNRGDTPLERHQLASPDCRFLSCAHGMRNS---------------------------------------------------------
G_aculeatus_ENSGACP00000024474            QVP-AERLARAGFYYTGNADRVCCFSCEKTVENWCRGDTPLERHKEVSPSCIFLSCTQRTNFN---------------------------------------------------------
O_latipes_ENSORLP00000012199              ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002256         PVN-PRHLAAAGFHYTGYKDRVKCFCCGLCVESWCVGDD-VKSPRWHRSNCEFILGQDCG---NQPI-DHM-------------------------VWLQVVCSAT----LCDHLVQL--
G_gallus_ENSGALP00000009239               -----------------------------------MADTAPVEGTHLRATC---------------------------------------------------------------------
T_guttata_ENSTGUP00000007779              -----------------------------------MGDAAPAQQPEPRAAR---------------------------------------------------------------------
M_domestica_ENSMODP00000021022            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000000487         ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000321377                 ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000019640          ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000000510         ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000021651         PVN-PIQLAIHGFYFTGVEDCVVCFSCENSVRNWKLGDKEGDK-KWHKPDCVFFNSLSQTVND---------------------------------------------------------
G_gorilla_ENSGGOP00000007398              ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000000466         PVD-KMKLSSNGFLYTGFKDRVKCFRCGQCVEGLNGTEN-MGLPGWHKPDCEFANGTDTTNVPLLRHKIQ--------------------------------------------------
X_tropicalis_ENSXETP00000016315           PYQTSDKLAWAGFFYVGPGDRVRCFSCGGEVDNWEPGDVPLTRHQLFFPHCSYVQGLS--------------------------------------------------------------
X_tropicalis_ENSXETP00000016312           PMANQRKLAQAGFSYVGPGDRVRCISCGGELEKWERWDVPLTRHQHSFPHCPYMQKLRDEGDG---------------------------------------------------------
M_musculus_ENSMUSP00000112867             SWT-PQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIG---------------------------------------------------------
G_gorilla_ENSGGOP00000008152              ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000058611             SWT-PQEMAAAGFYHTGVRLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIG---------------------------------------------------------
C_intestinalis_ENSCINP00000020067         ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000022142             SWT-PQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKLPIERHKKLRPECEFLQGKDVGNIG---------------------------------------------------------
X_tropicalis_ENSXETP00000057704           ----QNKLANAGFYYVGPEDRVRCFSCGGQFEMWEEWDFPLTRHQQTFPECPYLQELKAKGEW---------------------------------------------------------
H_sapiens_ENSP00000217169                 ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000023641          ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000034890           PYMKEWDLAQAGFYYVGPGDRVRCISCNAELEKWEKWDEPLTRHQHSFPDCAYVQEQRAQTTG---------------------------------------------------------
B_taurus_ENSBTAP00000004317               SWT-SQEMAEAGFYLTGTKSGIQCFCCSLILFGTSLQNTPMEHHKKFHPDCEFLLGKDVGNIA---------------------------------------------------------
M_mulatta_ENSMMUP00000012096              ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000048273          SWI-PQEMAASGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKRFHPDCGFLLNKDVGNIA---------------------------------------------------------
M_musculus_ENSMUSP00000113890             SWT-PQEMAAAGFYHTGVKLGVQCFCCSLILFSTRLRKLPIENHKKLRPECEFLLGKDVGNIG---------------------------------------------------------
R_norvegicus_ENSRNOP00000024483           SWT-PQEMAAAGFYYTGVRHGVQCFCCSLILFGTSLRKVPIESHRKLRPQCEFLSGKDVGNIG---------------------------------------------------------
H_sapiens_ENSP00000194097                 SWI-PQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKRFHPDCGFLLNKDVGNIA---------------------------------------------------------
C_intestinalis_ENSCINP00000010449         NIN-VRQVARAGFYFISYQDQVKCFSCGQICEDLQQYDD-MSLPQWHLPDCEHLHSLQPNRNNHANTPVQS-------------------------------------------------
M_musculus_ENSMUSP00000104503             ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000017359             SWI-PQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKRFHPDCGFLLNKDVGNIA---------------------------------------------------------
P_pygmaeus_ENSPPYP00000012543             ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000017749             ------------------------------------------------------------------------------------------------------------------------
D_melanogaster_FBpp0075254                PIA---------------------------------------------------------------------------------------------------------------------
A_aegypti_AAEL009074-PA                   ---------MAGVMMAQVLSTPRDFT----------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000018803           ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000005440         ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000002314             SWT-PQEMAAAGFHFTGVRAGVQCFCCGLILFGASLHKRPLDDHKRLRPDCGFLLGEDVGNVA---------------------------------------------------------
C_intestinalis_ENSCINP00000011648         ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007293-PA                   ----------------MASAVVSCIC----------------------------------------------------------------------------------------------
A_gambiae_AGAP007291-PA                   ----------------MASTVVSCIC----------------------------------------------------------------------------------------------
A_gambiae_AGAP007292-PA                   ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000002871            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002312         ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000008701         DLN-GKNLTNSGFYLEPGGSVIRCYSCGFRVENVTDTDS-GDSAQYHNDDCAHFKQLQSKQPIALKAPPQPPSVEGASFLPSMMDDLDLGLGNQDLQFSIYDPSLTEPYSGFSFENDQKL
A_gambiae_AGAP011326-PA                   ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000000543            -MESGGKPSLGQFILLGTSSVVTAVLYSVYRQKAQ-------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000002056             -MESGGRPSLCQFILLGTTSVVTAALYSVYRQKAR-------------------------------------------------------------------------------------
H_sapiens_ENSP00000264198                 -MESGGRPSLCQFILLGTTSVVTAALYSVYRQKAR-------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000009065              -MENGGRPSLCQFILLGTTSVVTAALYSVYRQKAR-------------------------------------------------------------------------------------
E_caballus_ENSECAP00000013139             -MEGGGRPSLGQVILLGTSSVVTAILYSVYRQKAQ-------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000000497          -MESGGRPSLCQFILLGTTSVVTAALYSVYRQKAR-------------------------------------------------------------------------------------

                                                  250       260       270       280       290       300       310       320       330       340       350       360
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
D_rerio_ENSDARP00000065554                APSTSGQTEEQVGYLNMGFTNLAPSSPISSRGVEDMSHQRPPACHNPG-MRREQERLDTFQ-NWT-----------------------------------------LA---TVTPAELAK
T_rubripes_ENSTRUP00000043752             NPS-ANQGEEPVGYLNMGFSAPPPSSPLISRGVEDMSHQR-PTCHNPN-MRREQDRLESFH-SWT-----------------------------------------LT---IITPAELAK
T_nigroviridis_ENSTNIP00000012883         NPS-ANPGEEPVGYLNMGFSAPPPSSPLGSRGVEDMSHQR-PTCHNPN-MRREQDRLDSFH-SWT-----------------------------------------LT---IITPAELAK
O_latipes_ENSORLP00000006992              NPS-GGQSEEAVGYLNMAFSAPPPSSPLASRGVEDLSHQR-PTCHNPS-MRREQDRLDSFQ-PWA-----------------------------------------IS---IITPAELAK
G_aculeatus_ENSGACP00000027283            -PA-VSQGEEPVGYLNMGFSAPPPSSPLSSRGVEDMSHQR-PTCHNPS-KRKEQDRLDSFH-PWT-----------------------------------------LS---IITPSELAK
T_guttata_ENSTGUP00000013125              SIA-LSPSLEQVGYFSGSFSS-FPQDPVTTRAAEDLSFLS-PKLHNNS-MRTEDARLCTFQ-SWP-----------------------------------------LT---FLSPTDLAK
O_anatinus_ENSOANP00000016616             TAT-ISPSLEPSGYFSGSFSS-FPLDPVTSRAIEDLSQPR-PHVDNSA-MSSEEARICTFQ-SWP-----------------------------------------LT---FLSPSALAK
G_gallus_ENSGALP00000035646               SMT-LSPSFEQVGYFSGSFSS-FPQDPVTTRAAEDLSHLR-SKLHNPS-MSTEEARLRTFH-AWP-----------------------------------------LM---FLSPAELAK
E_caballus_ENSECAP00000000598             THS-LSPTLEHSGSFSGSYSN-LSPNLVNSRAVEDFSPLR-TNPYSYA-MSTEEARFLTYH-MWP-----------------------------------------LT---FLSPSELAR
M_mulatta_ENSMMUP00000004536              AHS-LSPTLEHSSLFSGSYSS-LSPNPLNSRAVEDLSPSR-TNPYSYA-MSTEEARFLTYH-MWP-----------------------------------------LT---FLSPSELAR
H_sapiens_ENSP00000227758                 AHS-LSPTLEHSSLFSGSYSS-LSPNPLNSRAVEDISSSR-TNPYSYA-MSTEEARFLTYH-MWP-----------------------------------------LT---FLSPSELAR
P_pygmaeus_ENSPPYP00000004357             AHS-LSPTLEHSSLFSGSYSS-LSPNPLNSRAVEDFSSSR-TNPYSYA-MSTEEARFLTYH-MWP-----------------------------------------LT---FLSPSELAR
P_troglodytes_ENSPTRP00000007251          AHS-LSPTLEHSSLFSGSYSS-LSPNPLNSRAVEDISSSR-TNPYSYA-MSTEEARFLTYH-MWP-----------------------------------------LT---FLSPSELAR
C_familiaris_ENSCAFP00000022277           THS-ISPTLEH-GSFSGSHSN-LAANPVSSRAGEDFSPLS-TNPYSYA-MSTEEARFLTYH-MWP-----------------------------------------LT---FLSPSDLAR
E_caballus_ENSECAP00000010270             THS-LLPSLENSGYFSGSYSS-FPSNPVNSGPNHDFSALR-TSPYHCA-MNTEKARLLTFQ-MWP-----------------------------------------LT---FLSPTDLAK
M_domestica_ENSMODP00000000728            TRS-LSLSSEQSGYFSGSYSS-FPLEPVTSRGVEDLSPLN-TSPYSYS-MSTEEARILTYQ-AWP-----------------------------------------LT---FLSPLDLAR
A_carolinensis_ENSACAP00000012475         SPQ-QTPNLDQVGYFSGSFSS-VPQEL--PKLTEGISHVR-PKVANSA-MSSEEARLLTFK-TWP-----------------------------------------LT---FLSPSSLAK
C_familiaris_ENSCAFP00000022282           THA-QSPGLERSSYFSASYSS-FPVDPVDFRPSPAMSPWR-AGPSCVT-MKSEEDRLCTFQ-GWP-----------------------------------------LA---FPLPSALAR
P_troglodytes_ENSPTRP00000007250          THS-LLPGTENSGYFGGSYSN-SPSNPVNSRANQDFSALM-RSSYHCA-MNNENARLLTFQ-TWP-----------------------------------------LT---FLSPTDLAK
M_mulatta_ENSMMUP00000004533              THS-LLPGTENSGYFSGSYSS-FPSNPVNSRANQDFSALM-RSSYHCA-MNNEKARLLTFQ-TWP-----------------------------------------LT---FLSPTDLAK
H_sapiens_ENSP00000376897                 THS-LLPGTENSGYFRGSYSN-SPSNPVNSRANQDFSALM-RSSYHCA-MNNENARLLTFQ-TWP-----------------------------------------LT---FLSPTDLAK
M_musculus_ENSMUSP00000091422             AHS-SP--LER----GGIHSN-LCSSPLNSRAVEDFS-SR-MDPCSYA-MSTEEARFLTYS-MWP-----------------------------------------LS---FLSPAELAR
P_pygmaeus_ENSPPYP00000004355             THS-LLPGTENSGYFSGSYSS-FPSNPVNSRVNQDFSALM-RSSYHCA-MNNENARLLTFQ-TWP-----------------------------------------LT---FLSPTDLAK
R_norvegicus_ENSRNOP00000007702           MPS-GFAASESTGYFSGSYSS-FPSDPVNFRANQDCPAFS-TSPYHFA-MNTEKARLLTYQ-TWP-----------------------------------------LS---FLSPAELAK
R_norvegicus_ENSRNOP00000014560           AHS-LP--LEQ----GGIHSS-LPSNPLNSRAVEDFS-LR-MNPCSYA-MSTEEARFLSYS-MWP-----------------------------------------LS---FLSPAELAK
X_tropicalis_ENSXETP00000048002           MHA-ASAENDKVEAITLKYSS-IPQDPVTLRGIEDLSHVR-ISEY----MYTEEARLNSFQ-EWS-----------------------------------------NM---FLTPAELAK
M_musculus_ENSMUSP00000013949             MPL-SFASSENTGYFSGSYSS-FPSDPVNFRANQDCPALS-TSPYHFA-MNTEKARLLTYE-TWP-----------------------------------------LS---FLSPAKLAK
B_taurus_ENSBTAP00000034604               THS-LLPSLENSGYFSGSYSS-FPSNLLNSGPNQDFSALR-ISSYPCA-MNTEKARLLTFQ-MWP-----------------------------------------LT---FLSPTDLAK
O_cuniculus_ENSOCUP00000011948            AHS-LSPTVEPGGSFSGSYSS-LSANPLNSRTVEDFSPLR-TNPYSYS-MSSEEARFLTYH-MWP-----------------------------------------LS---FLSPSELAR
M_domestica_ENSMODP00000000705            SCS-LSPSSEQSGYFSGSYSS-FPLEPVTSRGVEDLSPLN-TSPYSYS-MSTEEARILTYQ-AWP-----------------------------------------LT---FLSPLDLAR
O_cuniculus_ENSOCUP00000008710            THS-FLPSWEHSGYYSGSYSS-LPSNPVNSRANQDFSAFR-VSPYHSA-MSTEKARLLTFQ-SWP-----------------------------------------LT---FLSPMDLAK
D_rerio_ENSDARP00000075338                -----------------------------------------------G-MRSEEERLQTFH-NWP-----------------------------------------SDA--AVSPEELAR
O_cuniculus_ENSOCUP00000014265            AHP-LFPTQGPCVSFSGSYPS-LSANPPNLTSV-DFSPLR-TS-LGYS-MSTEEAR---FY-YKP-----------------------------------------FS---FLLPSEFAR
G_gorilla_ENSGGOP00000008137              AHS-LSPTLEHSSLFSGSYSS-LSPNPLNSRAIEDISSSR-TNPYSYA-MSTEEARFLTYH-MWP-----------------------------------------LT---FLSPSELAR
B_taurus_ENSBTAP00000046955               ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000110746             --ENCVGNRNPF--APDRPPETHADYLLRTGQVVDISDT--IYPRNPA-MCSEEARLKSFQ-NWP-----------------------------------------DYA--HLTPRELAS
R_norvegicus_ENSRNOP00000009358           --ENCVGNRNHF--ALDRPSETHADYLLRTGQVVDISDT--IYPRNPA-MCSEEARLKTFQ-NWP-----------------------------------------DYA--HLSPRELAS
C_familiaris_ENSCAFP00000034255           --ENYLRNRDHF--VLDRPSETHADYLLRTGQVVDISDT--TYPENPA-MYSEEARLNSFQ-NWP-----------------------------------------DYV--HLTPRELAS
P_pygmaeus_ENSPPYP00000023167             --ENYLGSRNHF--ALDRPSETHADYLLRTGQVVDISDT--IYPRNPA-MYSEEARLKSFQ-NWP-----------------------------------------DYA--HLTPRELAS
B_taurus_ENSBTAP00000053449               --ENYLGNRNHF--VLERPSETHAHYLLRTGQVVDLSDT--VYPRNPV-MCSEEARLKSFH-NWP-----------------------------------------DYA--HLTPRELAR
C_intestinalis_ENSCINP00000000045         ---GPSEFRFTFVILTF---LTLYSTRPKVELATIASPYHEQLVRSLD-LRKESDRFKTYE-NWP-----------------------------------------AQN-RTVYASDLAR
E_caballus_ENSECAP00000017630             --ENYLGNRNHF--VLGRPSETHAEYLLRTGQVVDISDT--IYPRNPA-MCSEEARLKSFQ-NWP-----------------------------------------DYA--HLTPGELAS
H_sapiens_ENSP00000360242                 --ENYLGSRDHF--ALDRPSETHADYLLRTGQVVDISDT--IYPRNPA-MYSEEARLKSFQ-NWP-----------------------------------------DYA--HLTPRELAS
P_troglodytes_ENSPTRP00000038304          --ENYLGSRNHF--ALDRPSETHADYLLRTGQVVDISDT--IYPRNPA-MYSEEARLKSFQ-NWP-----------------------------------------DYA--HLTPRELAS
O_cuniculus_ENSOCUP00000008505            --ENYLGNRNHF--ALDRPSETHADYLLRTGQVVDISDT--IYPRNPA-MCSEEARLKSFQ-NWP-----------------------------------------DYA--HLTPRELAS
G_gallus_ENSGALP00000038337               --ENGSSNLALPS-ALEDLSDVEADYLLRTRQVVDMSDT--LYPKNPA-MCSEEARLKSFH-NWP-----------------------------------------PYG--LLTPKELAS
M_domestica_ENSMODP00000018715            --ENCSRNRNHF--ALERPSETHGEYLLRTGQVIDMSDT--IYPRNPS-MCSEEARLRSFQ-NWP-----------------------------------------DYA--HLTPQELAS
T_guttata_ENSTGUP00000003825              --ENGTSNSALPC-ALDD-PDVEADYLLRTRQVVDMSDS--LYPKNPA-MCSEETRLKSFH-NWP-----------------------------------------LND--RLTPQELAN
C_intestinalis_ENSCINP00000005161         WIRPDNTARENFMN-VTYLNLGEKNFFQRIELATISSVYHEQVLRSLD-LKKEGERMKSFE-NWP-----------------------------------------TQN-RTVNPSDLAR
T_nigroviridis_ENSTNIP00000006583         -------------------------------------------------MRREKDRIRTFR-EWP-----------------------------------------ADA--AVAPADLAK
X_tropicalis_ENSXETP00000035327           --MQNGFQNSAEDLAERSSSEIMADYLLRTGRVVDMSTP--KYPRHME-MCSEEARLQTFQ-NWP-----------------------------------------AYS--PLTPKELAN
G_aculeatus_ENSGACP00000003419            --------------------------------MTDDRGTAPRAPEAPR-MRGEGERLRTFG-RWP-----------------------------------------ADA--PVTSGELAG
T_rubripes_ENSTRUP00000011958             ------------------------------------------MLEEPR-MRREGDRIRTFQ-EWP-----------------------------------------ADA--AVAPADLAR
G_gorilla_ENSGGOP00000005705              THS-LLPGTENSGYFSGSXSN-SPSNPVNSRANQDFSALM-RSSYHCA-MNNENARLLTFQ-TWP-----------------------------------------LT---FLSPTDLAK
C_intestinalis_ENSCINP00000009820         ---PKIQGCRKFSMPLSFFV--------RIELATIASPYHEQLVRSLD-LRKESDRSKTYE-NWP-----------------------------------------AQN-RTVYASDLAR
X_tropicalis_ENSXETP00000030727           MHA-ASAENDKVEAITLKYSS-IPQDPVTLRGIEDLSHVR-ISEY----MYTEEARLNSFQ-EWS-----------------------------------------NM---FLTPAELAK
O_latipes_ENSORLP00000010149              ----SNPHMPLSNGGLHDGTEGYIDYQLRTRAIVDET----PYPRNRN-MKSEEARLETFS-SWP-----------------------------------------RSA--PVRPRDLAQ
X_tropicalis_ENSXETP00000029187           --------------------------------------------VPPN-MRSEAERQRSFR-AWP-----------------------------------------HTC-RTVSPAELAR
T_rubripes_ENSTRUP00000010298             ----PIPGTSLTNGSAYNEEAEDMEYRLRTGQVVDES----IYPVVPH-MRSEESRLHTFS-TWP-----------------------------------------LTA--PVSPCDLAQ
O_anatinus_ENSOANP00000006435             --EECPGNPSHH--ALERSSETHSDYLLRTRQVVDLSDT--VFPKNPA-MCSEEARLETFQ-NWP-----------------------------------------EYT--LLSPGQLAR
D_melanogaster_FBpp0086432                ------------------------PRSQESDNEGNSVVDSPESCSCPD-LLLEANRLVTFK-DWP-----------------------------------------NP---NITPQALAK
G_gorilla_ENSGGOP00000008442              --ENYLGSRNHF--ALDRPSETHADYLLRTGQVVDISDT--IYPRNPA-MYSEEARLKSFQ-NWP-----------------------------------------DYA--HLTPRELAS
A_carolinensis_ENSACAP00000011315         --ENGSASTSQQQPSLDESSDLDADYLLRTGQVVDLSGS--LYPRNPA-MCSEEARLRTFH-NWP-----------------------------------------PYA--PVTPQDLAH
A_aegypti_AAEL006633-PA                   -----------------------------------------------E-LKREEHRLATYV-NWP-----------------------------------------IS---HISPSSLAK
T_nigroviridis_ENSTNIP00000018867         ----QLIDASLANNSAYNEE-----------AVVDES----IYPVAPH-MKSEKSRLQTFS-SWP-----------------------------------------SAV--PVRPQDLAQ
D_rerio_ENSDARP00000013586                ---------NSIQSPDYDEEAENREFLLRTGEVVDES----MYPVVPH-MKSEEARLSTFN-NWP-----------------------------------------ADS--PVRPEDLAE
G_aculeatus_ENSGACP00000024474            ----LSCENRLTNGFSYNEEEEDLEYRLRRGEVVDES----TYPMAPH-MKSEEARLQTLS-TWP-----------------------------------------SSS--PVRPRDLAQ
O_latipes_ENSORLP00000012199              ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002256         ---GQG---------------------------------------------------------------------------------------------------------GIYSETLA-
G_gallus_ENSGALP00000009239               -----------------------------------------CHLFNYS-MRDEARRLRTFS-QWP-----------------------------------------RSS--PVSAWDLAK
T_guttata_ENSTGUP00000007779              -----------------------------------------RRLFEAS-MRSVARRLRTFQ-QWP-----------------------------------------RTA--PVSARDLVE
M_domestica_ENSMODP00000021022            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000000487         ---------------------------------------------SIE-LFKEENRRETFK-TWS-----------------------------------------AAF-NDEFVKELAR
H_sapiens_ENSP00000321377                 ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000019640          ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000000510         ---------------------------------------------SIE-LFKEENRRETFK-TWS-----------------------------------------AAF-NDEFVKELAR
C_intestinalis_ENSCINP00000021651         -------------TNISTPNHQDMNHFVNTNPTEVVFET--MLLKRLT-HKSIKLNIRTFD-YWP-----------------------------------------HQL-REVNTAALAK
G_gorilla_ENSGGOP00000007398              ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000000466         -------------------------------------------------QNLPSLQNASFVQSIP-----------------------------------------NQDQTTLSAGELLK
X_tropicalis_ENSXETP00000016315           ---------------------IRHSYFMEEGVGPGFLDTNILGKE--GDMSDEYSRIQSYQ-AVK-----------------------------------------EHF-PNQTPIKLAW
X_tropicalis_ENSXETP00000016312           ----------KENQSKVCAGPIKEG---ESGTTVPLSSSSNLEKKPCGYMSDEYSRLESYR-GHGQHFNYWN----------------------------------QQRLAKQTSDELAW
M_musculus_ENSMUSP00000112867             -----------------------------KYDIRVKSPEKML-RGGKARYHEEEARLESFE-DWP-----------------------------------------FYA-HGTSPRALSA
G_gorilla_ENSGGOP00000008152              ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000058611             -----------------------------KYDIRVKRPEKML-RGGKARYHEEEARLESFE-DWP-----------------------------------------FYA-HGTSPRVLSA
C_intestinalis_ENSCINP00000020067         --------------------------------MAEIDRQDITGLASPSLTQHKEAKTQILP-----------------------------------------------------------
M_musculus_ENSMUSP00000022142             -----------------------------KYDIRVKSPEKML-RGGKARYHEEEARLESFE-DWP-----------------------------------------FYA-HGTSPRVLSA
X_tropicalis_ENSXETP00000057704           ----------------------------KDCHYEPGLGSNILMEKPLGDLSDERRRLETFR-GHSGLFPYNRVKFLAIQSPNILGKKSHYDMTNMYSRADTYRGHHKHFLPYMKEWDLAQ
H_sapiens_ENSP00000217169                 ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000023641          ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000034890           ----------TQDQSQVCPMPIKEG---ESGIPARYSGSHNPGEKPLGDMNDEYSRLETYR-GHS-----------------------------------------QYF-PMANQRRLAQ
B_taurus_ENSBTAP00000004317               -----------------------------KYDVRVQKPENTLRRDDKARYQEEKARLESFK-NWP-----------------------------------------FYA-QGTSPRELSA
M_mulatta_ENSMMUP00000012096              ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000048273          -----------------------------KYDIRVKNLKSRL-RGGKMRYQEEEARLASFR-NWP-----------------------------------------FYV-QGISPCVLSE
M_musculus_ENSMUSP00000113890             -----------------------------KYDIRVKSPEKML-RGDKARYHEEEARLESFE-DWP-----------------------------------------FYA-HGTSPRVLSA
R_norvegicus_ENSRNOP00000024483           -----------------------------KYDIRVKNPETLP-RGGRARYHEEEARLESFE-DWP-----------------------------------------FYA-HGTSPRVLSA
H_sapiens_ENSP00000194097                 -----------------------------KYDIRVKNLKSRL-RGGKMRYQEEEARLASFR-NWP-----------------------------------------FYV-QGISPCVLSE
C_intestinalis_ENSCINP00000010449         ---------------------------------GLSRPNENATFRSLPTRRPAHSNVHSSS-SLP------------------------------------------RQPTTITINQPRI
M_musculus_ENSMUSP00000104503             ---------------------------------------------------------------------------------------------------------------MFSPADLFR
P_pygmaeus_ENSPPYP00000017359             -----------------------------KYDIRVKNLKSRL-RGGKMRYQEEEARLASFK-NWP-----------------------------------------FYV-QGIPPCVLSE
P_pygmaeus_ENSPPYP00000012543             ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000017749             ------------------------------------------------------------------------------------------------------------------------
D_melanogaster_FBpp0075254                ------------------------FDQVDNNTNATQLFKNNINKTRMNDLNREETRLKTFT-DWP-----------------------------------------LD---WLDKRQLAQ
A_aegypti_AAEL009074-PA                   ----------------------------DNKVKEDNAYGHTATSVPIS-YHTEVARLESFR-GWM-----------------------------------------VS---FISKTELAR
C_familiaris_ENSCAFP00000018803           ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000005440         ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000002314             -----------------------------KYEVRVRKPPGTL-RGDAARYREEEARLKSFK-DWP-----------------------------------------FYA-QATAPRELSA
C_intestinalis_ENSCINP00000011648         ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007293-PA                   --------------------------------REIAEYRVTHDTPEEC-LNYEVNRLRTFP-LWT-----------------------------------------VP---YIYPEELAR
A_gambiae_AGAP007291-PA                   --------------------------------REIAEYRVTHIVPEEC-LNYEINRLRTYDLLWT-----------------------------------------VP---YIYPEELAR
A_gambiae_AGAP007292-PA                   ----------------------------MESHDNTERQERTGLCNELN-YNQEINRLRTYFPLWT-----------------------------------------VP---YIYPEELAR
O_cuniculus_ENSOCUP00000002871            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002312         ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000008701         KYLPQSVNDVSMVPNTSENNEVSDEECPQIYLAQVYSAEHREFLHTLN-LNKESGRLKSFR-NWP-----------------------------------------DN---SLDKTLLAK
A_gambiae_AGAP011326-PA                   -------------------------------------------------MSSASGS-------------------------------------------------------EVQPA----
O_cuniculus_ENSOCUP00000000543            -------------------------------------------------VSRELKGAKKIHLGED-----------------------------------------LKSILSEAPGKCVP
P_pygmaeus_ENSPPYP00000002056             -------------------------------------------------VSQELKGAKKVHLGED-----------------------------------------LKSILSEAPGKCVP
H_sapiens_ENSP00000264198                 -------------------------------------------------VSQELKGAKKVHLGED-----------------------------------------LKSILSEAPGKCVP
M_mulatta_ENSMMUP00000009065              -------------------------------------------------VSQELKGAKKVHLGED-----------------------------------------LKSILSEAPGKCVP
E_caballus_ENSECAP00000013139             -------------------------------------------------VAQELKGARRIHLGED-----------------------------------------LKSILSEAPGKCVP
P_troglodytes_ENSPTRP00000000497          -------------------------------------------------VSQELKGAKKVHLGED-----------------------------------------LKSILSEAPGKCVP

                                                  370       380       390       400       410       420       430       440       450       460       470       480
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
D_rerio_ENSDARP00000065554                AGLYYLGQGDRV----------ACFSCGGQLG--SWEPGDRAVSEHQRHYPNCRFVRGDRA-----------------------------------------------------------
T_rubripes_ENSTRUP00000043752             AGFYYLSQGDRV----------ACFSCGGQLS--NWEPGDRAMSEHQRHYPNCRFVRGDRA-----------------------------------------------------------
T_nigroviridis_ENSTNIP00000012883         AGFYYLSQGDRV----------ACFSCGGQLN--NWEPGDRAMSEHQRHYPNCRFVRGDRA-----------------------------------------------------------
O_latipes_ENSORLP00000006992              AGFYYLGQNDRV----------ACFSCGGQLS--NWEPGDRAVSEHQRHYPNCRFVRGDRA-----------------------------------------------------------
G_aculeatus_ENSGACP00000027283            AGFYYLGQGDRV----------ACFSCGGQLS--NWEPGDRAVSEHQRHYPNCRFLSSGAA-----------------------------------------------------------
T_guttata_ENSTGUP00000013125              AGFYYLGTADKV----------ACFTCGGQLY--NWEPKDNAVSEHRRHYPNCPFVENLIR-----------------------------------------------------------
O_anatinus_ENSOANP00000016616             AGFYYTGPGDRV----------ACFTCGGKLS--NWEPKDDAMSEHRRHFPGCPFLERQTR-----------------------------------------------------------
G_gallus_ENSGALP00000035646               AGLYYLGTADKV----------ACFTCGGQLS--NWEPKDNAMSEHRRHFPNCPFVENLMR-----------------------------------------------------------
E_caballus_ENSECAP00000000598             AGFYYIGPGDRV----------ACFACGGTLS--NWEPKDDAMSEHRRHFPNCPFLENSL------------------------------------------------------------
M_mulatta_ENSMMUP00000004536              AGFYYIGPGDRV----------ACFACGGKLS--NWEPKDDAMSEHRRHFPNCPFLENSL------------------------------------------------------------
H_sapiens_ENSP00000227758                 AGFYYIGPGDRV----------ACFACGGKLS--NWEPKDDAMSEHRRHFPNCPFLENSL------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004357             AGFYYIGPGDRV----------ACFACGGKLS--NWEPKDDAMSEHRRHFPNCPFLENSL------------------------------------------------------------
P_troglodytes_ENSPTRP00000007251          AGFYYIGPGDRV----------ACFACGGKLS--NWEPKDDAMSEHRRHFPNCPFLENSL------------------------------------------------------------
C_familiaris_ENSCAFP00000022277           AGFYYIGPGDKV----------ACFACGGTLS--NWEPKDDAMSEHRRHFPNCPFLENSL------------------------------------------------------------
E_caballus_ENSECAP00000010270             AGFYYIGPGDRV----------ACFACGGKLS--NWEPKDDAMSEHLRHFPNCPFVENQFE-----------------------------------------------------------
M_domestica_ENSMODP00000000728            AGFYYIGPGDMV----------ACFACGGKLS--NWEPKDDAMSEHRRHFPHCPFLESQIQ-----------------------------------------------------------
A_carolinensis_ENSACAP00000012475         AGFYYIGPADKV----------ACFVCGGHLG--NWEPKDNAMSEHRRHFPTCPFVE-QTQ-----------------------------------------------------------
C_familiaris_ENSCAFP00000022282           AGFYYVGPGDRV----------ACFACGGKLS--NWEPDDDALSEHLRHFPDCPFVEGQLQ-----------------------------------------------------------
P_troglodytes_ENSPTRP00000007250          AGFYYIGPGDRV----------ACFACGGKLS--NWEPKDNAMSEHLRHFPKCPFIENQLQ-----------------------------------------------------------
M_mulatta_ENSMMUP00000004533              AGFYYVGPGDRV----------ACFACGGKLS--NWEPKDNAMSEHLRHFPKCPFIENQLQ-----------------------------------------------------------
H_sapiens_ENSP00000376897                 AGFYYIGPGDRV----------ACFACGGKLS--NWEPKDNAMSEHLRHFPKCPFIENQLQ-----------------------------------------------------------
M_musculus_ENSMUSP00000091422             AGFYYIGPGDRV----------ACFACGGKLS--NWEPKDDAMSEHRRHFPHCPFLENTS------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004355             AGFYYIGPGDRV----------ACFACGGKLS--NWEPKDNAMSEHLRHFPKCPFIENQLQ-----------------------------------------------------------
R_norvegicus_ENSRNOP00000007702           AGFYYTGPGDRV----------ACFACGGKLS--NWDRKDDPLSEHRRHFPSCPFLKDVGQ-----------------------------------------------------------
R_norvegicus_ENSRNOP00000014560           AGFYYTGPGDRV----------ACFACGGKLS--NWEPNDDPLSEHRRHFPHCPFLENTS------------------------------------------------------------
X_tropicalis_ENSXETP00000048002           AGFYFVGPGDKV----------ACFTCDGKLN--NWEPNDNAMSEHRRHFPNCPFVKSSTR-----------------------------------------------------------
M_musculus_ENSMUSP00000013949             AGFYYIGPGDRV----------ACFACDGKLS--NWERKDDAMSEHQRHFPSCPFLKDLGQ-----------------------------------------------------------
B_taurus_ENSBTAP00000034604               AGFYYIGPGDRV----------ACFACGGTLS--NWEPKDDAMSEHLRHFPNCPFLGNQLQ-----------------------------------------------------------
O_cuniculus_ENSOCUP00000011948            AGFYYIGPGDRV----------ACFACGGKLS--NWEPKDDAMSEHRRHFPKCPFLENSL------------------------------------------------------------
M_domestica_ENSMODP00000000705            AGFYYIGPGDMV----------ACFACGGKLS--NWEPKDDAMSEHRRHFPHCPFLESQIQ-----------------------------------------------------------
O_cuniculus_ENSOCUP00000008710            AGFYYVGPGDRV-