10        20        30        40        50        60        70        80        90       100       110       120
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000262982                 ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICEADRVAIKANIVH
M_mulatta_ENSMMUP00000025796              ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICEADRVAIKANIVH
P_pygmaeus_ENSPPYP00000012414             ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICEADRVAIKANIVH
P_troglodytes_ENSPTRP00000023391          ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICEADRVAIKANIVH
B_taurus_ENSBTAP00000047927               ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICEADRVAIKANIVH
E_caballus_ENSECAP00000013844             ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICEADRVAIKANIVH
C_familiaris_ENSCAFP00000016619           --------XSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICEADRVAIKANIVH
M_musculus_ENSMUSP00000002790             ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICEADRVAIKANIVH
R_norvegicus_ENSRNOP00000010210           ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICEADRVAIKANIVH
M_domestica_ENSMODP00000020339            ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KCQ--DNVIKVC---A--SVTFKNYIKRNW--RIIEDE-----PNKICEADRIAIKANIVH
O_anatinus_ENSOANP00000010219             ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGSQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIIEDE-----PNKIFEADRIAIKANIVH
T_guttata_ENSTGUP00000009114              ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGSQNYPLLLLTLLE--KSQ--ENVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICESDRIAIKANIVP
G_gallus_ENSGALP00000007487               ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLETVEGSQNYPLLLLTLLE--KSQ--ENVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKIFESDRIAIKANIVP
X_tropicalis_ENSXETP00000003710           ------MELSEANLQGLTEYLKKTLDPDPAVRRPAEKYLESVEGNQNYPLLLLTLVE--RSQ--DNVIKVC---S--AVTFKNYIKRNW--RIIEDE-----PNNICEADRIAIKSSIIN
G_aculeatus_ENSGACP00000001261            ------MELNDANLQSLTEFLRKTLDPDPTVRRPAEKFLESVEGNLNYPLLLLTMLE--KSQ--DTVIRVC---A--AVTFKNYIKRNW--RIVEDE-----PNKVSDQDRTAIKANIVN
T_nigroviridis_ENSTNIP00000017660         ------MELNEGNLQTLTEFLKKTLDPDPGVRRPAEKFLESVEGNQNYPLLLLMLLE--KSQ--NNVIRVC---A--AVTFKNYIKRNW--RIVEDE-----PNKVSDPDRTAIKANIIN
O_latipes_ENSORLP00000000743              ------MELNDANLQSLTEVLRKTLDPDPNARRPAEKFLESVEGNQNYSLLLLTLLE--KSQ--DNVIRVC---A--AVMFKNYIKRNW--RIVEDE-----PNKISEADRTAIKANIVN
D_rerio_ENSDARP00000022858                ------MELNDGNLQTLTEYLQKTLSADPAVRRPAEKFLESVEGNQNYPILLLAVLE--KSQ--NEVIRVC---S--AVTFKNYIKRNW--RIVEDE-----PNKISDPDRTAIKANIVN
T_rubripes_ENSTRUP00000013203             ------MELNDGNLQTLTEFLRKTLDPDPAVRRPAEKFLESVEGNQNYPLLLLTLLE--K-Q--DNVIRVC---A--AVTFKNYIKRNW--RIVEDE-----PNKVSNPDRTAIKANIIN
O_cuniculus_ENSOCUP00000004737            ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PSKICEADRVAIKANIVH
G_gorilla_ENSGGOP00000010615              ------MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLE--KSQ--DNVIKVC---A--SVTFKNYIKRNW--RIVEDE-----PNKICEADRVAIKANIVH
A_carolinensis_ENSACAP00000015734         ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000004657         ------------------------LKADFIFSQIAEKYLENVEGNPGYAVMLLKLVDDGRQQQNPGMVPLA---A--AITFKNFVKRNW--RVNEDE-----ASKVSEQDRNTIKCTVVD
A_gambiae_AGAP010711-PA                   ------MEINENNFERLASYLQQTLNPDPEVRRPAERFIESIEVSQNYPLLCLHLID--RPQ-VDMTIRVA---A--AIAFKNFIKRNWGFHLDNDG-----PNKVSESDRTGIKGLIVP
A_aegypti_AAEL008741-PA                   ------MEVTENNFERLASYLQQTLSPDPEVRRPAERFIESIEVSQNYPLLCLNLID--RLQ-VDITIRVA---A--AIAFKNFVKRNWGYHLDNDG-----PDKVAESDRNGIKQMIVP
D_melanogaster_FBpp0080484                ------MEVTEANLQLLAGYLQQTLSADPNVRRPAEKLLESTELQQNYPILLLNLID--KAQ-MDMTTRVA---G--AIAFKNYIKRNWAAHLDSDG-----PDRIHESDRNTIKTLIVT
S_cerevisiae_YGL238W                      ----------MSDLETVAKFLAESVIAS--TAKTSERNLRQLETQDGFGLTLLHVIA--STN-LPLSTRLA---G--ALFFKNFIKRKW---VDENG-----NHLLPANNVELIKKEIVP
C_elegans_Y48G1A.5                        -------------MEQIGAALQQTLEPDAAIRKRGEEALRSLQSNPGYIIQILQLVVNEQQQ-IAPQIRIA---A--AVALKNFVKRNW----GPAP-----EVEMGQEDEEQFRSMLLE
D_melanogaster_FBpp0076408                -----------MEAQKLTELLRATIDPNPEQRKAAEDQLAQIHKIIGFVPTILQIVM--QTT-VEQPVRQA---G--AVYLKNLINSSWSDHEAKPGEPI--PFSIHEQDRAMIRGAIVD
B_taurus_ENSBTAP00000039739               -----------MDPNTIIEALRGTMDPA--LREAAERQLNEAHKSLNFVSTLLQITM--SEQ-LDLPVRQA---G--VIYLKNMITQYWPDRETAPGDIS--PYTIPEEDRHCIRENIVE
H_sapiens_ENSP00000369042                 -----------MDPNTIIEALRGTMDPA--LREAAERQLNEAHKSLNFVSTLLQITM--SEQ-LDLPVRQA---G--VIYLKNMITQYWPDRETAPGDIS--PYTIPEEDRHCIRENIVE
C_familiaris_ENSCAFP00000010873           -----------MDPNTIIEALRGTMDPA--LREAAERQLNEAHKSLNFVSTLLQITM--SEQ-LDLPVRQA---G--VIYLKNMITQYWPDRETAPGDIS--PYTIPEEDRHCIRENIVE
M_musculus_ENSMUSP00000081782             -----------MDPNTIIEALRGTMDPA--LREAAERQLNEAHKSLNFVSTLLQITM--SEQ-LDLPVRQA---G--VIYLKNMITQYWPDREATPGDIA--PYTIPEEDRHCIRENIVE
P_troglodytes_ENSPTRP00000048248          -----------MDPNTIIEALRGTMDPA--LREAAERQLNEAHKSLNFVSTLLQITM--SEQ-LDLPVRQA---G--VIYLKNMITQYWPDRETAPGDIS--PYTIPEEDRHCIRENIVE
M_musculus_ENSMUSP00000046759             -----------MDLNRIIQALKGTIDPK--LRIAAETELNQSYKIINFAPSLLRIIV--SDH-VEFPVRQA---A--AIYLKNMVTQYWPDREPPPGEVIF-PFNIHENDRQQIRDNIVE
R_norvegicus_ENSRNOP00000014004           -----------MDPNTIIEALRGTMDPA--LREAAERQLNEAHKSLNFVSTLLQITM--SEQ-LDLPVRQA---GKSVIYLKNMITQYWPDREATPGDIS--PYTIPEEDRHCIRENIVE
C_intestinalis_ENSCINP00000017536         MPDCTHAQILTMDPNKILNALEATMNPN--LRKEAEEQLDQMHKIAGFSPLLIQLVM--SDE-VQMAVRQS---G--AIYLKNLCVHSWHERTDKDGTPITDVFSIHENDRGLIRSNIVK
X_tropicalis_ENSXETP00000052227           -----------MDPNILIEALRGTMDPA--LREAAERQLNESHKSLHFVSTLLQITM--SEQ-LDLPVRQA---GKSVIYLKNMITQYWPDREVTPGELP--PHTIPEEDRHCIRENIVE
O_latipes_ENSORLP00000008906              -----------MDPESLIEALRGTMDPN--LREAAERQLNEGHSQVNFLSILLRVTM--SEQ-LDLPVRQA---G--VIYLKNMITQHWSDGDGSCTETS--VNNIPEEDRIFIRDNIVE
O_cuniculus_ENSOCUP00000006136            -----------MDPNTIIEALRGTMDPA--LREAAERQLNEAHKSLNFVSTLLQITM--SEQ-LDLPVRQA---GXXVIYLKNMITQYWPDRETAPGDIS--PYTIPEEDRHCIRENIVE
D_rerio_ENSDARP00000051878                -----------MDLNTLIEALRGTMDAN--LREAAERQLNEGHSQVNFMSTLLQLTM--TEQ-LDLPVRQA---G--VIYLKNMVTQFWTEGDNANTEAP--TSTIPETDRQFIRDNIVE
G_aculeatus_ENSGACP00000020688            -----------MDPESLVEALRGTMDPN--LREAAERQLNEGHSQVNFLSTLLRVTM--SDQ-LDLPVRQA---G--VIYLKNMITQHWSDGEASSTETP--VNNIPDDDRLFIRDNIVE
A_carolinensis_ENSACAP00000009310         -----------MDPNTIIEALRGTMDST--LRETAERQLNEAHKSVNFVSTLLQITM--SEQ-LDLPVRQA---GKCVIYLKNMITQYWPDRETTPGDIP--PYSIPEEDRHCIRENIVE
H_sapiens_ENSP00000256079                 -----------MDLNRIIQALKGTIDPK--LRIAAENELNQSYKIINFAPSLLRIIV--SDH-VEFPVRQA---A--AIYLKNMVTQYWPDREPPPGEAIF-PFNIHENDRQQIRDNIVE
M_mulatta_ENSMMUP00000001816              -----------MDLNRIIQALKGTIDPK--LRIAAENELNQSYKIINFAPSLLRIIV--SDH-VEFPVRQA---A--AIYLKNMVTQYWPDREPPPGEAIF-PFNIHENDRQQIRDNIVE
P_troglodytes_ENSPTRP00000008198          -----------MDLNRIIQALKGTIDPK--LRIAAENELNQSYKIINFAPSLLRIIV--SDH-VEFPVRQA---A--AIYLKNMVTQYWPDREPPPGEAIF-PFNIHENDRQQIRDNIVE
P_pygmaeus_ENSPPYP00000005014             -----------MDLNRIIQALKGTIDPK--LRIAAENELNQSYKIINFAPSLLRIIV--SDH-VEFPVRQA---A--AIYLKNMVTQYWPDREPPPGEAIF-PFNIHENDRQQIRDNIVE
C_familiaris_ENSCAFP00000015868           -----------MDLNLIIQALKGTIDPK--LRIAAENELNQSYKIINFAPSLLRIIV--SDH-VEFPVRQA---A--AIYLKNMVTQYWPDREPPPGEAVF-PFNIHENDRQQIRDNIVE
E_caballus_ENSECAP00000014130             --------------------------------------------------------------------------G--VIYLKNMITQYWPDRETAPGDIS--PYTIPEEDRHCIRENIVE
B_taurus_ENSBTAP00000018760               -----------MDLNRIIQALKGTIDPK--LRIAAENELNQSYKIINFAPSLLRIIV--SEH-VEFPVRQA---A--AIYLKNMVTQYWPDREPPPGEAIF-PFNIHENDRQQIRDNIVE
T_nigroviridis_ENSTNIP00000012237         -----------MDPDALIEALRGTMDPT--LREAAERQLNEGHTQVNFVSTLLRITM--SDQ-LDLPVRQA---G--VIYLKNMITQHWSDGDGSGTETP--VKNIPDEDRQFIRDNIVE
E_caballus_ENSECAP00000011294             -----------TS-HRIIQALKGTIDPK--LRIAAENELNQSYKIINFAPSLLRIIV--SDH-VEFPVRQA---A--AIYLKNMVTQYWPDREPPPGEAIF-PFNIHENDRQQIRDNIVE
O_anatinus_ENSOANP00000009316             -----------------------------------------AHKSVNFVSTLLQITM--SEQ-LDLPVRQA---G--VIYLKNMITQYWPDRETTPGEMP--PYTIPEEDRHCIRENIVE
G_gallus_ENSGALP00000009312               ------------------------------------------HKSVNFVSTLLQITM--SEQ-LDLPVRQA---G--VIYLKNMITQYWPDRETAPGEIP--PYSIPEEDRHCIRENIVE
T_guttata_ENSTGUP00000008467              -----------------------------------------AHKSVNFVSTLLQITM--SEQ-LDLPVRQA---GNGVIYLKNMITQYWPDRESAPGEIP--PYSIPEEDRHCIRENIVE
A_carolinensis_ENSACAP00000012797         -----------MDPNRIIQALKGTIDPK--LRLAAENELNQSYKIINFAPSLLQIIV--SDQ-VEFPVRQA---A--AIYLKNMVTQYWPDREPPPGEVIF-PFNIHENDRQQIRDNIVE
M_domestica_ENSMODP00000009743            -----------------------------------------AHKSVNFVSTLLQITM--SEQ-LDLPVRQA---GNSVIYLKNMITQYWPDRETTPGEIP--PYTIPEEDRHCIRENIVE
T_rubripes_ENSTRUP00000032909             -----------MDPNRIIQALKGTIDPN--MRIAAENELNQSYKIINFAPTLLQIIM--SEQ-VEFPVRQA---A--AIYLKNMVSQYWQDREPSLGEVIF-PFNIHENDRQQIRDHIVE
G_aculeatus_ENSGACP00000025426            -----------MDPNRIIQALKGTIEPN--LRIAAENELNQSYKIINFAPTLLQIIM--SEQ-VEFPVRQA---A--AIYLKNMVSQYWQDREPCLGEVVF-PFNIHENDRQQIRDHIVE
O_latipes_ENSORLP00000015709              -----------MDPNRIIQALKGTIDPN--LRIAAENELNQSYKIINFAPTLLQIIM--SEQ-VEFPVRQA---A--AIYLKNMVSQYWQDREPCVGEVVF-PFNIHENDRQQIRDHMVE
T_rubripes_ENSTRUP00000044627             -----------MDPDALVEALRGTMDPS--LREAAERQLNEGHTQVCFVSTLLQITM--SDQ-LDLPVRQA---G--VIYLKNMITQHWSDGDGSGTETP--VNNIPDEDRQFIRDSIVE
T_nigroviridis_ENSTNIP00000010026         -----------MDPNRIIQALKGTIDPS--MRIAAENELNQSYKIINFAPTLLQIIM--SEQ-VEFPVRQA---A--AIYLKNMVSQYWQDREPSLGQAIF-PFNIHENDRQQIREHIVE
D_rerio_ENSDARP00000024402                -----------MDPNRIIQALKGTIDPN--LRLAAENELNQSYKIINFAPTLLQIIV--SEQ-VEFPVRQA---A--AIYLKNMVSQYWQDREPTLGEVVF-PFNIHENDRGQIRENMVE
G_gallus_ENSGALP00000021094               -----------KDPNRIIQALKGTINAK--LRIAAENELNQSYKIINFAPSLLQIIV--SDQ-VEFPVRQAGKVA--AIYLKNMVTQYWPDREPPPGEAVF-PFNIHENDRQQIRDNIVE
T_guttata_ENSTGUP00000011802              ------------DPNRIIQALKGAIDPK--LRVAAENELSHSYKIINFAPSLLQIIV--SDQ-VEFPVRQAGSLA--AIYLKNMVTQYWPDREPPPGEAVF-PFNIHENDRQQIRDNIVE
S_cerevisiae_YJR132W                      -----------MDITELLQCFACTLDHNAAVRTNAETHLKNASKVPGFLGACLDIIA--ADE-VPENIKLS---A--SLYFKNKITYGWSAGARQGSNELL-DSHVDPDEKPVVKDMLIK
A_aegypti_AAEL004441-PA                   -----MAQNADLIKQAMFEELQKILNPDGDIRRQAEERLAQLKYTEGYGVYLAEITI--NQN-LDLPLRQL---A--SVMLKQYVEDCWAVENEDGQSSNS-ALLVNNEAKIAIKTILPQ

                                                  130       140       150       160       170       180       190       200       210       220       230       240
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000262982                 LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
M_mulatta_ENSMMUP00000025796              LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
P_pygmaeus_ENSPPYP00000012414             LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
P_troglodytes_ENSPTRP00000023391          LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
B_taurus_ENSBTAP00000047927               LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
E_caballus_ENSECAP00000013844             LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
C_familiaris_ENSCAFP00000016619           LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
M_musculus_ENSMUSP00000002790             LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
R_norvegicus_ENSRNOP00000010210           LMLS----SPEQI--QKQLSDAISIVGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
M_domestica_ENSMODP00000020339            LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
O_anatinus_ENSOANP00000010219             LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFRSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHST-D-----ASAL
T_guttata_ENSTGUP00000009114              LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
G_gallus_ENSGALP00000007487               LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIDLCSTHAN-G-----ASAL
X_tropicalis_ENSXETP00000003710           LMLS----SPEQI--QKQFSDAISIIGREDFPQ-KWPNLLTEMVNRFQSGDFHVINGVLHTAHSLFKRYRHEFKSSELWTEIKLVLDTFAAPLTDLFKATIELCNTHAN-D-----VNAL
G_aculeatus_ENSGACP00000001261            LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVTRFRSGDFHIINGVLRTAHSLFKRYRHEFKSNELWSEIKLVLDTFALPLTELFKATIELCQTHAA-D-----VNAL
T_nigroviridis_ENSTNIP00000017660         LMLT----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVTRFQSGDFHIINGVLRTAHSLFKRYRHEFKSNELWSEIKLVLDTFASPLTDLFKATIDLCQTHAT-D-----VNAL
O_latipes_ENSORLP00000000743              LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVTRFRSGDFHIINGVLRTAHSLFKRYRHEFKSNELWSEIKLVLDTFAQPLTELFKATIELCQTHAT-D-----VNVL
D_rerio_ENSDARP00000022858                LMLT----SPEQI--QKQLSDAISIIGREDFPL-KWPDLLTEMVNRFQSGDFHIINGVLRTAHSLFKRYRHEFKSNELWSEIKLVLDTFAQPLTELFKATIELCQTHAT-D-----INAL
T_rubripes_ENSTRUP00000013203             LMLT----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVTRFRSGDFHIINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDTFAPPLTELFKATIDLCQTHAT-D-----VNAL
O_cuniculus_ENSOCUP00000004737            LMLS----SPEQI--QKQLSDAISIIGREDFPQ-KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
G_gorilla_ENSGGOP00000010615              LMLS----SPEQI--QKQXXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHAN-D-----ASAL
A_carolinensis_ENSACAP00000015734         ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000004657         LMLT----SPKQY--QKQLSEAISIIGREDFPE-KWPSLLEDMNKKFQSADFHIINGVLQTAHSLFKRYRHEFRSDKLWTEIKHVLTTFAAPLTELFVNTVKLAEQHSA-D-----KESL
A_gambiae_AGAP010711-PA                   MMLK----SPAAI--QKQLSDAVSIIGKYDFPT-KWPELMDEMIEKFATGDFHIINGVLQTAHSLFKRYRYEFKSQELWEEIKYVLDKMAKPLTDLLQATLGLAEAHAG-N-----KEAL
A_aegypti_AAEL008741-PA                   LMLK----SPSSI--QKQLSDAVSIIGKYDFPL-KWPQLMDEMIEKFATGNFSVINGVLQTAHSLFKRYRYEFKSQELWEEIKFVLDKLAKPLTDLLQATLGLAEAHAN-N-----EEAL
D_melanogaster_FBpp0080484                LMLH----SPVAL--QKQLSDAVSIIGKYDFPK-KWPQLIDEMVERFASGDFNVINGVLQTAHSLFKRYRYEFKSQALWEEIKFVLDRMAKPLTDLLQATMQLTKVHEN-N-----AGAL
S_cerevisiae_YGL238W                      LMIS----LPNNL--QVQIGEAISSIADSDFPD-RWPTLLSDLASRLSNDDMVTNKGVLTVAHSIFKRWRPLFRSDELFLEIKLVLDVFTAPFLNLLKTVDEQITANEN-N-----KASL
C_elegans_Y48G1A.5                        AMFN----TKSNV--QEILSNALYLIAQRDFPE-KWPDLVPYLSKFLNGADLNHLVASLASMEQIFRKFRFESKSAELWKELKKCLLSTQEPLTLLLRNMMEVGQRKDQLG-----ADEI
D_melanogaster_FBpp0076408                AIVH----APELI--RVQLSVCVNHIIKSDFPG-RWPQVVDSISIYLQNQDVNGWNGALVTMYQLVKTY--EYKRHEERTPLNEAMNLLLPMIYQLMVRLLA--------E-----QSEQ
B_taurus_ENSBTAP00000039739               AIIH----SPELI--RVQLTTCIHHIIKHDYPS-RWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLVAAMQHFLPVLKDRFIQLLS--------D-----QSDQ
H_sapiens_ENSP00000369042                 AIIH----SPELI--RVQLTTCIHHIIKHDYPS-RWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLVAAMQHFLPVLKDRFIQLLS--------D-----QSDQ
C_familiaris_ENSCAFP00000010873           AIIH----SPELI--RVQLTTCIHHIIKHDYPS-RWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLVAAMQHFLPVLKDRFIQLLS--------D-----QSDQ
M_musculus_ENSMUSP00000081782             AIIH----SPELI--RVQLTTCIHHIIKHDYPS-RWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLVAAMQHFLPVLKDRFIQLLS--------D-----QSDQ
P_troglodytes_ENSPTRP00000048248          AIIH----SPELI--RVQLTTCIHHIIKHDYPS-RWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLIAAMQHFLPVLKDRFIQLLS--------D-----QSDQ
M_musculus_ENSMUSP00000046759             GIIR----SPDLV--RVQLTMCLRVIIRHDFPG-HWPAVVDKIDYYLQSPNSGSWLGSLLCLYQLVKTY--EYKKAEEREPLLAAMQIFLPRIQQQILQLLP--------D-----ASHY
R_norvegicus_ENSRNOP00000014004           AIIH----SPELI--RVQLTTCIHHIIKHDYPS-RWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLVAAMQHFLPVLKDRFIQLLS--------D-----QSDQ
C_intestinalis_ENSCINP00000017536         ALIH----APDII--RNQLTVVVQNIIKHDFPQ-VWPNVVNEVHFHLQSEAPREWMGALLTLYQLVKTY--EFKKPDARGPVIEAMKLLLPVMLQLFRKLME--------D-----PSAS
X_tropicalis_ENSXETP00000052227           AIIH----SPELI--RVQLTTCIHHIIKHDYPN-RWTAVVEKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLIAAMQHFLPMLKDRYIQLLA--------D-----PSEQ
O_latipes_ENSORLP00000008906              AIIH----SPERI--RVQLTTCIHHMIKHDYPG-KWTAIVDKIGFYLQSDNSAGWLGILLCLYQLVKNY--EYKKPEERQPLVAAMHIFMPMLKDRFIQLLP--------D-----HSSD
O_cuniculus_ENSOCUP00000006136            AIIH----SPELI--XXQLTTCIHHIIKHDYPN-RWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLVAAMQHFLPVLKDRFIQLLS--------D-----QSDQ
D_rerio_ENSDARP00000051878                AIIQ----SPERI--RVQLTTCIHHMIKHDYPG-RWTAIVDKIGLYLQSDNSSYWLGILLCLYQLVKNY--EYKKPEERQPLVAAMQIFMPMLKDRFIQLLP--------D-----TSAD
G_aculeatus_ENSGACP00000020688            AIIH----SPERI--RVQLTTCIHHMIKHDYPG-KWTTIVDKIGFYLQSDNTSGWLGILLCLYQLVKNY--EYKKPEERQPLVAAMHIFMPMLKERFIQLLP--------D-----HSSD
A_carolinensis_ENSACAP00000009310         AIIH----SPELI--RVQLTTCIHHIIKHDYPN-RWTAVVEKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERTPLIAAMQHFLPVLKDRFIQLLP--------D-----SSDQ
H_sapiens_ENSP00000256079                 GIIR----SPDLV--RVQLTMCLRAIIKHDFPG-HWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTY--EYKKAEEREPLIIAMQIFLPRIQQQIVQLLP--------D-----SSYY
M_mulatta_ENSMMUP00000001816              GIIR----SPDLV--RVQLTMCLRAIIKHDFPG-HWPAVVDKIDYYLQSQSSGSWLGSLLCLYQLVKTY--EYKKAEEREPLIIAMQIFLPRIQQQIVQLLP--------D-----SSYY
P_troglodytes_ENSPTRP00000008198          GIIR----SPDLV--RVQLTMCLRAIIKHDFPG-HWPAVVDKIDYYLQSQSSASWLGSLLCLYQLVKTY--EYKKAEEREPLIIAMQIFLPRIQQQIVQLLP--------D-----SSYY
P_pygmaeus_ENSPPYP00000005014             GIIR----SPDLV--RVQLTMCLRAIIKHDFPG-HWPAVVDKIDYYLQSQSSASWLGSLLCLYQLVKTY--EYKKAEEREPLIIAMQIFLPRIQQQIVQLLP--------D-----SSYY
C_familiaris_ENSCAFP00000015868           GIIR----SPDLV--RVQLTMCLRAIIKYDFPG-HWPAVVDKIDYYLQSQSSGSWLGSLLCLYQLVKTY--EYKKAEEREPLIAAMQIFLPRIQQQIMQLLP--------D-----SSHY
E_caballus_ENSECAP00000014130             AIIH----SPELI--RVQLTTCIHHIIKHDYPS-RWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERNPLVAAMQHFLPVLKDRFIQLLS--------D-----QSDQ
B_taurus_ENSBTAP00000018760               GIIR----SPDLV--RVQLTMCLRAIIKYDFPG-HWPAVVDKIDYYLQSQSSGSWLGSLLCLYQLVKTY--EYKKAEEREPLIAAMQIFLPRIQQQIMQLLP--------D-----SSHY
T_nigroviridis_ENSTNIP00000012237         AIIH----SPERI--RVQLTTCIHHMIKHDYPG-KWTAIVDKIGFYLQSDNSAGWLGILLCLYQLVKNY--EYKKPEERQPLVAAMHIFMPMLKDRFIQLLL--------D-----HSSD
E_caballus_ENSECAP00000011294             GIIR----SPDLV--RVQLTMCLRAIIKYDFPG-HWPAVVDKIDYYLQSQSSGSWLGSLLCLYQLVKTY--EYKKAEEREPLIAAMQIFLPRIQQQIMQLLP--------D-----SSHC
O_anatinus_ENSOANP00000009316             AIIH----SPELI--RVQLTTCIHHIIKHDYPS-RWTAVVDKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLIAAMQHFLPLLKDRFIQLLS--------D-----QSDQ
G_gallus_ENSGALP00000009312               AIIH----SPELI--RVQLTTCIHHIIKHDYPS-RWTAVVEKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLIAAMQHFLPVLKDSFIQLLS--------D-----PSDQ
T_guttata_ENSTGUP00000008467              AIIH----SPELI--RVQLTTCIHHIIKYDYPS-RWTAVVEKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLIAAMQHFLPVLKDSFIQLLN--------D-----PSDQ
A_carolinensis_ENSACAP00000012797         GIIR----SPDLV--RAQLTMCLRFIIKHDFPG-HWTAVVDKIGYYLQSPNSGNWLGSLLCLYQLVKTY--EYKKAEERDPLIAAMQIFLPRIQQQMIQLLP--------D-----NSHY
M_domestica_ENSMODP00000009743            AIIH----SPELI--RVQLTTCIHHIIKHDYPS-RWTAVVDKIGFYLQSENSACWLGILLCLYQLVKNY--EYKKPEERSPLVAAMQHFLPVLKDRFIQLLP--------D-----QSDQ
T_rubripes_ENSTRUP00000032909             GIIR----CPESI--RVQLTMCLRAIIKHDFPG-RWTAIVDKIGMYLQSQNSGSWYGTLLVLYQLVKTY--EYRKADEREPLLAAMHIFLPRIQQLISQVLA--------D-----SSIF
G_aculeatus_ENSGACP00000025426            GIIR----SPESI--RAQLTMCLRAIIKHDFPG-RWTAIVDKLSMYLQAQNGGSWYGSLLALYQLVKTY--EYRKAEEREPLLAAMQIFLPRIQQLISQLLA--------D-----ATIF
O_latipes_ENSORLP00000015709              AIIR----SPESI--RAQLTVCLRIIIKHDFPG-RWTAVVDKISMYLQSQNTSGWYGSLLALYQLVKTY--EYRKAEERQPLLAAMQIFLPRIQQLISQLLV--------D-----STIF
T_rubripes_ENSTRUP00000044627             AIIH----SPERI--RVQLTTCIHHMIKHDYPG-KWTTIVDKIGFYLQSDNRAGWLGILLCLYQLVKNY--EYKKPEERAPLVAAMHIFMPMLKDRFIQLLP--------D-----HSVD
T_nigroviridis_ENSTNIP00000010026         GIIR----CPESV--RVQLTMCLRAIIKHDFPG-RWTAIVDKIGLYLQSQNSGSWYGTLLVLYQLVKTY--EYRKADEREPLLAAMHIFLPRIQQLISQVLA--------D-----SSIF
D_rerio_ENSDARP00000024402                AIIR----CPESI--RAQLTVCLRAIIKHDFPG-RWTGVVDKINLYLQSQNSGSWYGSLLALYQLVKNY--EFKKAEERDPLLAAMQIFLPRLQQLITQLLS--------D-----ATFI
G_gallus_ENSGALP00000021094               GIIR----SPDLVSHRAQLTMCLRAIIKHDFPG-HWTAVVDKIGYYLQSQNSGSWLGSLLCLYQLVKTY--EYKKAEERDPLIAAMQIFLPRIQQQMIQLLP--------D-----NSHY
T_guttata_ENSTGUP00000011802              GIIR----SPDLVSTRAQLTMCLRAIIKHDFPG-HWTAVVDKIGYYLQSPNSGSWLGSLLCLYQLVKTY--EYKKAEERDPLIAAMQIFLPRIQQQMIQLLP--------D-----NSHY
S_cerevisiae_YJR132W                      TMVSVSKTSPRCI--RV-LKSALTVIISEDYPSKKWGNLLPNSLELLANEDITVTYVGLLCLAEIFRTY--RWKNNDERQDLEELILNYFPALLNYGANVLF--------QDGKYMNNEQ
A_aegypti_AAEL004441-PA                   GLYD----PNSKI--RSVVAYSISNIASYDWPN-DWQELFDIIVKCL-SGNENSVHGAMKVLVEF---------TLDLDKQIAEVGPMILSEVYRIFAAQ----------DVYSVSTRSY

                                                  250       260       270       280       290       300       310       320       330       340       350       360
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000262982                 RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQRYLPR
M_mulatta_ENSMMUP00000025796              RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQRYLPR
P_pygmaeus_ENSPPYP00000012414             RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQRYLPR
P_troglodytes_ENSPTRP00000023391          RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQRYLPR
B_taurus_ENSBTAP00000047927               RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQRYLPR
E_caballus_ENSECAP00000013844             RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQRYLPR
C_familiaris_ENSCAFP00000016619           RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQLYLPR
M_musculus_ENSMUSP00000002790             RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQRYLPR
R_norvegicus_ENSRNOP00000010210           RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQRYLPR
M_domestica_ENSMODP00000020339            KVLFSSLILIAKLFYSLNFQDLPEFF--EDNMETWMNNFHNLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQPYLPR
O_anatinus_ENSOANP00000010219             KVLFSSLVLIAKLFYSLNFQDLPEFF--EDNMETWMNNFHNLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFRPYLPR
T_guttata_ENSTGUP00000009114              KVLFSSLILIAKLFYSLNFQDLPEFF--EDNMETWMTNFHSLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQPYLPR
G_gallus_ENSGALP00000007487               KVLFSSLINIKMHIYAFPSQDLPEFF--EDNMETWMTNFHSLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQPYLPR
X_tropicalis_ENSXETP00000003710           KVLFSSLILIAKLFHSLNFQDLPEFF--EDNMETWMTNFHNLLTLDNKL--------------LQTDDE-EEAGLLETLKSQICDNAALY---------------AQK-YDEEFQPYLPR
G_aculeatus_ENSGACP00000001261            KVLFSSLTLISKLFYSLNFQDLPEFF--EDNMETWMTNFHGLLTLDNKL--------------LQTNDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQPYLPR
T_nigroviridis_ENSTNIP00000017660         KVLFSSLILICKLFYSLNFQDLPEFF--EDNMETWMTNFHALLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQPYLPR
O_latipes_ENSORLP00000000743              KVLFSSLTLISKLFYSLNFQDLPEFF--EDNMETWMTNFHGLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQPYLPR
D_rerio_ENSDARP00000022858                KVLFSSLTLISKLFYSLNFQDLPEFF--EDNMETWMTNFHNLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQPYLPR
T_rubripes_ENSTRUP00000013203             KVLFSSLILICKLFYSLNFQDLPEFF--EDNMETWMTNFHALLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQPYLPS
O_cuniculus_ENSOCUP00000004737            RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQRYLPR
G_gorilla_ENSGGOP00000010615              RILFSSLILISKLFYSLNFQDLPEFF--EDNMETWMNNFHTLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQRYLPR
A_carolinensis_ENSACAP00000015734         -------------------QDLPEFF--EDNMETWMMNFHNLLTLDNKL--------------LQTDDE-EEAGLLELLKSQICDNAALY---------------AQK-YDEEFQPYLPR
C_intestinalis_ENSCINP00000004657         KVLFSSLVLISKVFYSLNYQDLPEFF--EDNMETWMKHFHALLTTDNAI--------------LHTQGE-EEAGLVELLQSQICDNVALY---------------AQK-YDEEFAKFLPQ
A_gambiae_AGAP010711-PA                   SVIYNSLVLVCKVFFSLNSQDLPEFF--EDNMETWMKAFHGLLTVDVPC--------------LKTDDD-EDAGVLEHLRSQICENLCMY---------------ALK-YDEEFSPYMPQ
A_aegypti_AAEL008741-PA                   KVIYGSLVLVCKVFYSLNSQDLPEFF--EDNMDTWMKAFHGMLTIDIPC--------------LKTAED-EDAGVLEHLRSQICENLCLY---------------AQK-YDEEFGPYMPQ
D_melanogaster_FBpp0080484                KVIYGSLVLVNKVFFSLNSQDLPEFF--EDNINTWMGAFIQQLAADVPS--------------LRTADD-EDAGVLEHLRAQVCENICLY---------------AKK-YDEEFKPFMEQ
S_cerevisiae_YGL238W                      NILFDVLLVLIKLYYDFNCQDIPEFF--EDNIQVGMGIFHKYLSYSNPL--------------LEDPDETEHASVLIKVKSSIQELVQLY---------------TTR-YEDVFGPMINE
C_elegans_Y48G1A.5                        AQWLRVLLLIAKVYHSLCSQEIPEYF--EDHLKDWMPHFLHLVQIDAP---------------TQTSNS-GEPTTLDELKHEICEIFTLY---------------SQR-YEEEISEFVPD
D_melanogaster_FBpp0076408                SVLLQKQIL--KIYYALTQYTLPLDLITKEIFSQWMEICRQVADRAVP-------------DSSHL-DD-DERTEFPYWK---TKKWALHIMVRMFERYGSPSNVVSEKYQKFAEWYLPT
B_taurus_ENSBTAP00000039739               SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPN------------ETLQV-EE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
H_sapiens_ENSP00000369042                 SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPN------------ETLQV-EE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
C_familiaris_ENSCAFP00000010873           SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPN------------ETLQV-EE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
M_musculus_ENSMUSP00000081782             SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPN------------ETLQV-EE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
P_troglodytes_ENSPTRP00000048248          SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPN------------ETLQV-EE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
M_musculus_ENSMUSP00000046759             SVLLQKQIL--KIFYALVQYALPLQLVNHQTMTTWMEIFRTIIDRTVPP------------ETLQI-DE-DDRPELVWWK---CKKWALHIVARLFERYGSPGNVTKE-YFEFSEFFLKT
R_norvegicus_ENSRNOP00000014004           SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWVEILKTVVNRDVPN------------ETLQV-EE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
C_intestinalis_ENSCINP00000017536         SALLQKQLL--KILYALIQYSLPMDLFNEKIMDEWINIMRVIIDTPPPP------------DTLQV-DE-LERCELPWWK---SKKWAVHFLARMFERYGSPGSVTKE-YNAFSEFFLKR
X_tropicalis_ENSXETP00000052227           SVLIQKQIF--KIFYALVQYTLPLELINQQNLAEWIEILKTVVDRDVPA------------ETLQV-DE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
O_latipes_ENSORLP00000008906              SVLIQKQIF--KILYALFQYNLPLELINRQNLTEWMEILKAVVDRDVP-------------------------PKPPPPK-------TTRILARLFERYGSPGNTTKE-YAEFAELFLKE
O_cuniculus_ENSOCUP00000006136            SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPN------------ETLQV-EE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
D_rerio_ENSDARP00000051878                SVLVQKQIL--KILYALFQYNLPLELINRQNLTEWMEILKTVVDRDVPQ------------ETLQV-DE-DERPELPWWK---CKKWALHILARLFERYGSPGNTTKE-YTEFAELFLKG
G_aculeatus_ENSGACP00000020688            SVLIQKQIF--KILYALFQYNLPLELINRQNLTEWMEILKTVVDRDVPP------------ETMQI-DE-DERPELPWWK---CKKWALHIMARLFERYGSPGNTTKE-YAEFAELFLKE
A_carolinensis_ENSACAP00000009310         SVLIQKQIF--KIFYALVQYTLPLELINQQNLAEWIEILKTVVDRDVPA------------ETLQV-DE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
H_sapiens_ENSP00000256079                 SVLLQKQIL--KIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPP------------ETLHI-DE-DDRPELVWWK---CKKWALHIVARLFERYGSPGNVTKE-YFEFSEFFLKT
M_mulatta_ENSMMUP00000001816              SVLLQKQIL--KIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPP------------ETLHI-DE-DDRPELVWWK---CKKWALHIVARLFERYGSPGNVTKE-YFEFSEFFLKT
P_troglodytes_ENSPTRP00000008198          SVLLQKQIL--KIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPP------------ETLHI-DE-DDRPELVWWK---CKKWALHIVARLFERYGSPGNVTKE-YFEFSEFFLKT
P_pygmaeus_ENSPPYP00000005014             SVLLQKQIL--KIFYALVQYALPLQLVNNQTMTTWMEIFRTIIDRTVPP------------ETLHI-DE-DDRPELVWWK---CKKWALHIVARLFERYGSPGNVTKE-YFEFSEFFLKT
C_familiaris_ENSCAFP00000015868           SVLLQKQIL--KIFYALVQYALPLQLVNNQTMTAWMEIFRTIIDRTVPP------------ETLQI-DE-DDRPELVWWK---CKKWALHIVARLFERYGSPGNVTKE-YFEFSEFFLKT
E_caballus_ENSECAP00000014130             SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPN------------ETLQV-EE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
B_taurus_ENSBTAP00000018760               SVLIQKQIL--KIFYALVQYALPLQLVNNQTMTAWMEIFRTIIDRTVPP------------ETLQI-DE-DDRPELVWWK---CKKWALHIVARLFERYGSPGNVTKE-YFEFSEFFLKT
T_nigroviridis_ENSTNIP00000012237         SVLVQKQIF--KILYALFQYNLPLELINRQNLTEWMEILKTVVDRDVPL------------ETAQI-DE-DERPELPWWK---CKKWALHILARLFERYGSPGNTTKE-YTEFAELFLKE
E_caballus_ENSECAP00000011294             SVLLQKQIL--KIFYALVQYALPLQLVNNQTMTAWMEIFRTIIDRTVPP------------ETLQI-DE-DDRPELVWWK---CKKWALHIVARLFERYGSPGNVTKE-YFEFSEFFLKT
O_anatinus_ENSOANP00000009316             SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWIEILKTVVNRDVPA------------ETLQV-EE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
G_gallus_ENSGALP00000009312               SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWIEILKTVVDRDVPA------------ETLQV-DE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
T_guttata_ENSTGUP00000008467              SVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWIEILKTVVDRDVPA------------ETLQV-DE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
A_carolinensis_ENSACAP00000012797         SVLLQKQIL--KNFYALVQYALPLQLMNNQTMTQWMEIFRSVIDRSVPP------------ETLQI-DE-DDRPELVWWK---CKKWALRIVARLFERYGSPGNVTKE-YFAFSEFFLKT
M_domestica_ENSMODP00000009743            SVLIQKQIF--KIFYALVQYTLPLELINQANLTEWIEILKTVVNRDVPP------------ETLQV-EE-DDRPELPWWK---CKKWALHILARLFERYGSPGNVSKE-YNEFAEVFLKA
T_rubripes_ENSTRUP00000032909             SVLIQKQIL--KIFHALIQYSLPFQLIDNTVMTQWMEIFRDVMDRAVPS------------ETLEV-DE-DDRPELAWWK---CKKWALRIITRLFERYGSPGHVSKE-YFDFANFFLKT
G_aculeatus_ENSGACP00000025426            SVLIQKQIL--KIFYALVQYSLPLQLINNTLMTQWMEILRAIMDRDVPA------------ETLEV-DE-DDRPELAWWK---CKKWALRIITRLFERYGSPGNVTKE-YYEFADFFLKT
O_latipes_ENSORLP00000015709              SVLVQKQIL--KVFHALVQYSLPLQLISNTVMTQWMEVFRSTMDRDVPA------------ETLEV-DE-DDRPELAWWK---CKKWAMRILTRLFERYGSPGNVTQD-YSEFADFFLKT
T_rubripes_ENSTRUP00000044627             SVLVQKQIF--KILYALFQYNLPLELINRQNLTEWMEILKTVVDRDVPP------------ETAQI-KE-DELPELPWWK---CKKWALHILARLFERYGSPGNTTKE-YTEFAELFLKE
T_nigroviridis_ENSTNIP00000010026         SVLIQKQIL--KIFHALIQYSLPFQLINNTVMTQWMEIFRDIMDRAVPS------------ETLEV-DE-DDRPELAWWK---CKKWALRIITRLFERYGSPGNVTKE-YCDFANFFLMT
D_rerio_ENSDARP00000024402                SVLIQKQIL--KIFHALV------QLINNTVMTHWMEILRTVVDRDVPAIWFSECLRGGFQETLEA-DE-DDRPELIWWK---CKKWALHILTRIFERYGSPGNVTKE-YVEFADFFLKT
G_gallus_ENSGALP00000021094               SVLLQKQIL--KIFYALVQYALPLQLVNNQTMTQWMEIFRTIIDRNVPP------------ETLQI-DE-DDRPELVWWK---CKKWALHIVARLFERYGSPGNVTKE-YFEFSEFFLKT
T_guttata_ENSTGUP00000011802              SVLLQKQIL--KIFYALVQYALPLQLVNNQTMTQWMEIFRTIIDRNVPL------------ETLQI-DE-DDRPELVWWK---CKKWALHIVARLFERYGSPGNVTKE-YFEFSDFFLKT
S_cerevisiae_YJR132W                      IGELVKLII--KIYKFVSYHDLPFTLQRSESFTPWACFFVSIIQQPLPQ------------EVLSISDI-EVRSKNPWVK---CKKWALANLYRLFQRYASTSLTRKFQYDEFKQMYCEE
A_aegypti_AAEL004441-PA                   AVEILNSLLRSIITHIDSKQEQSNIL--NPTLPTFMQKMIEGLTVPNGP---------------HSSFQ-LKTQIIKVLKYMISD------------------------MPKFANQYLAA

                                                  370       380       390       400       410       420       430       440       450       460       470       480
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000262982                 FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
M_mulatta_ENSMMUP00000025796              FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
P_pygmaeus_ENSPPYP00000012414             FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
P_troglodytes_ENSPTRP00000023391          FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
B_taurus_ENSBTAP00000047927               FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
E_caballus_ENSECAP00000013844             FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
C_familiaris_ENSCAFP00000016619           FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
M_musculus_ENSMUSP00000002790             FVTAIWNLLVTTGR--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
R_norvegicus_ENSRNOP00000010210           FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
M_domestica_ENSMODP00000020339            FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
O_anatinus_ENSOANP00000010219             FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
T_guttata_ENSTGUP00000009114              FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKHLFEDQNIL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
G_gallus_ENSGALP00000007487               FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKHLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
X_tropicalis_ENSXETP00000003710           FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDPSTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
G_aculeatus_ENSGACP00000001261            FVTAIWNLLVSTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKHLFEDQNTL-TSICEKVIVPN---MEFRSADEEAFEDNSEEYIRRDLE-GSDIDTR
T_nigroviridis_ENSTNIP00000017660         FVTAIWNLLVSTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERTHYKHLFEDQNTL-TSICEKVIVPN---MEFRSADEEAFEDNSEEYIRRDLE-GSDIDTR
O_latipes_ENSORLP00000000743              FVTAIWNLLVSTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQSTL-TSICEKVIVPN---MEFRSADEEAFEDNSEEYIRRDLE-GSDIDTR
D_rerio_ENSDARP00000022858                FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKHLFEDQNVL-TSICEKVIVPN---MEFRSADEEAFEDNSEEYIIRDLE-GSDIDTR
T_rubripes_ENSTRUP00000013203             FVTAIWSLLVSTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERTHYKQLFEDQNTL-TSICEKVIVPN---MEFRSADEEAFEDNSEEYIRRDLE-GSDIDTR
O_cuniculus_ENSOCUP00000004737            FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
G_gorilla_ENSGGOP00000010615              FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKNLFEDQNTL-TSICEKVVVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
A_carolinensis_ENSACAP00000015734         FVTAIWNLLVTTGQ--------EVKYDL----------------LVSNAIQFLAS-VCERPHYKHLFEDQNIL-TSICEKVIVPN---MEFRAADEEAFEDNSEEYIRRDLE-GSDIDTR
C_intestinalis_ENSCINP00000004657         FVTAVWNLLVNTGK--------EVKYDL----------------LVSNAIGFLRS-VCERQQYKSLFEDEGVL-VSICEKVVVPN---MEFRTADEEQFEDNPEEYIRRDLE-GSDVDTR
A_gambiae_AGAP010711-PA                   FVTAVWELLVKSHI--------HTKYDA----------------LVSNALRFLST-VAERTHYRHLFEDPNVL-ASICEKVIIPN---MDFRVSDEELFEDNPEEYIRRDIE-GSDVETR
A_aegypti_AAEL008741-PA                   FVTAVWELLVNTGI--------QTKYDT----------------LVSNALNFLST-VADRNHYRHLFEDPNVL-ASICEKVIIPN---MDFRVSDEELFEDNPEEYIRRDIE-GSDVETR
D_melanogaster_FBpp0080484                FVTAVWELLVKTSL--------HTKYDS----------------LVSHALQFLSV-VADRQHYQSIFENPEIL-AQICDKVVIPN---LDIRPSDEEIFEDSPEEYIRRDIE-GSDIDTR
S_cerevisiae_YGL238W                      FIQITWNLLTSISN--------QPKYDI----------------LVSKSLSFLTA-VTRIPKYFEIFNNESAM-NNITEQIILPN---VTLREEDVELFEDDPIEYIRRDLE-GSDTDTR
C_elegans_Y48G1A.5                        IILAVWNLLKSTGP--------DTRYDT----------------MVCAALEFLSM-VSQRQYYEGHFTGEGVL-KTLAENVCVQN---LLLRQQDMELFEDEPLDYMKRDIE-GTDVGTR
D_melanogaster_FBpp0076408                FSQGVLEVLLKILD--------QYRNRV-YVSPR----------VLTDVLNYLKNAVSHAYTWKLI---KPHM-VAVIQDVIFPI---MSFTDSDQELWESDPYEYIRLKFDIFEDYATP
B_taurus_ENSBTAP00000039739               FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHALTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
H_sapiens_ENSP00000369042                 FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHALTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
C_familiaris_ENSCAFP00000010873           FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHALTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
M_musculus_ENSMUSP00000081782             FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHALTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
P_troglodytes_ENSPTRP00000048248          FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHALTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
M_musculus_ENSMUSP00000046759             YAVGIQQVLLKILD--------QYRQKE-YIAPR----------VLQQAFNYLNQGVVHAVTWKQM---KPHI-QNISEDVIFSV---MCYKDEDEELWQEDPYEYIRMKFDIFEDYASP
R_norvegicus_ENSRNOP00000014004           FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHALTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
C_intestinalis_ENSCINP00000017536         YTVSILQVLLKIFD--------AYRNKE-YVAPR----------VLQQALHFLDQSVSHAHTWKVM---KGAY-HDLLKDIIFPL---MCFTDEDKEVWEDDPHEYIRMKFDIFEDFLSP
X_tropicalis_ENSXETP00000052227           FAVGVQQVLLKVLY--------QYKEKQ-YIAPR----------VLQQTLNYLNQGVSHAMTWKNL---KPHI-QGIIQDVIFPL---MCYTDSDEELWQEDPYEYIRMKFDVFEDFISP
O_latipes_ENSORLP00000008906              YAVGAQQVLLKVLY--------QYKEKL-YVAPR----------VLQQTLNYINQGIAHALTWKNL---KPHI-HGMVQDVVFPL---MCYTDSDEELWQEDPYEYIRMKFDVFEDFISP
O_cuniculus_ENSOCUP00000006136            FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHALTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKF-----XXXX
D_rerio_ENSDARP00000051878                YAVAAQQVLLKVLY--------QYKEKQ-YVAPR----------VLQQTLNYINQGIAHAVTWKNL---KPHI-QGIVQDVVFPL---MCYTDSDEELWQEDPYEYIRMKFDVFEDFISP
G_aculeatus_ENSGACP00000020688            YAVPAQQVLLKVLY--------QFKEKQ-YVAPR----------VLQQTLNYINQGIAHALTWRNL---KPHI-QGIIQDVVFPL---MCYTDSDEELWQEDPYEYIRMKFDVFEDFISP
A_carolinensis_ENSACAP00000009310         FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHAVTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
H_sapiens_ENSP00000256079                 YAVGIQQVLLKILD--------QYRQKE-YVAPR----------VLQQAFNYLNQGVVHSITWKQM---KPHI-QNISEDVIFSV---MCYKDEDEELWQEDPYEYIRMKFDIFEDYASP
M_mulatta_ENSMMUP00000001816              YAVGIQQVLLKILD--------QYRQKE-YVAPR----------VLQQAFNYLNQGVVHSITWKQM---KPHI-QNISEDVIFSV---MCYKDEDEELWQEDPYEYIRMKFDIFEDYASP
P_troglodytes_ENSPTRP00000008198          YAVGIQQVLLKILD--------QYRQKE-YVAPR----------VLQQAFNYLNQGVVHSVTWKQM---KPHI-QNISEDVIFSV---MCYKDEDEELWQEDPYEYIRMKFDIFEDYASP
P_pygmaeus_ENSPPYP00000005014             YAVGIQQVLLKILD--------QYRQKE-YVAPR----------VLQQAFNYLNQGVVHSVTWKQM---KPHI-QNISEDVIFSV---MCYKDEDEELWQEDPYEYIRMKFDIFEDYASP
C_familiaris_ENSCAFP00000015868           YAVGIQQVLLKILD--------QYRQKE-YVAPR----------VLQQAFNYLNQGIVHSVTWKQM---KPHI-QNISEDVIFSV---MCYKDEDEELWQEDPYEYIRMKFDIFEDYASP
E_caballus_ENSECAP00000014130             FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHALTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
B_taurus_ENSBTAP00000018760               YAVGIQQVLLKILD--------QYRQKE-YVAPR----------VLQQAFNYLNQGIVHSVTWKQM---KPHI-QNISEDVIFSV---MCYKDEDEELWQEDPYEYIRMKFDIFEDYASP
T_nigroviridis_ENSTNIP00000012237         YAVSAQQVLLKVLY--------QYKEKQ-YVAPR----------VLQQTLNYINQGIAHALTWRNL---KPHI-QGIIQDVVFPL---MCYTDSDDELWQEDPYEYIRMKFDVFEDFISP
E_caballus_ENSECAP00000011294             YAVGIQQVLLKILD--------QYRQKE-YVAPR----------VLQQAFNYLNQGIVHSVTWKQM---KPHI-QNISEDVIFSV---MCYKDEDEELWQEDPYEYIRMKFDIFEDYASP
O_anatinus_ENSOANP00000009316             FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHAVTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
G_gallus_ENSGALP00000009312               FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHAVTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
T_guttata_ENSTGUP00000008467              FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHAVTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
A_carolinensis_ENSACAP00000012797         YAVGIQQVLLKILD--------QYRRKE-YVAPR----------VLQQTLNYLNQGVHHCITWKQM---KPHM-QALCEDVIFSL---MCYRDEDEELWQEDPYEYIRMKFDVFEDYASP
M_domestica_ENSMODP00000009743            FAVGVQQVLLKVLY--------QYKEKQ-YMAPR----------VLQQTLNYINQGVSHAVTWKNL---KPHI-QGIIQDVIFPL---MCYTDADEELWQEDPYEYIRMKFDVFEDFISP
T_rubripes_ENSTRUP00000032909             YAVGILQVLLKVMD--------QHRQKQ-YVTPR----------ILQQCISYLNQGLSHSLTWKQM---KPHM-PAICQEVIFPL---MCYKDEDEKLWQEDPYEYIRMKFNLYDDHTSP
G_aculeatus_ENSGACP00000025426            YAMGIQQVLLKVMD--------QHRQKE-YVTPR----------VLQQCLNYLNQGLSHSLTWKHM---KPHM-QTICQEVIFPL---MCYKDEDEKLWQEDPYEYIRMKFNLYDDQALP
O_latipes_ENSORLP00000015709              YAVGIQQVLLKVVD--------QHRQRH-YVTPR----------VLQLCLNYLSQGLSHSLTWKHI---KPHM-QTIIQDVIFPL---MCYKDEDERLWQEDPYEYVRMKFNLYDDHALP
T_rubripes_ENSTRUP00000044627             FAVSAQQVLLKVLY--------QYKEKQ-YVAPR----------VLQQTLNYINQGIAHALTWRNL---KPHI-QGIIQDVVFPL---MCYTDSDDRLWQEDPYEYIRMKFDVFEDFISP
T_nigroviridis_ENSTNIP00000010026         YAVGILQVILKVID--------QHRQKH-YVTPR----------ILQQCITYLKQGLSHSLTWKHM---KPHM-PAICQEVIFPL---MCYKEEDEKLWQDDPYEYIRMKFNLYDEHISP
D_rerio_ENSDARP00000024402                YALGIQQVLLKVME--------QHRQRQ-YVSPR----------VLQQTLSFMTQGVSHSLTWRQM---KPHMQQTITHELVFPL---MCYKDEDERLWQEDPYEYIRMKFNVYDDHVSP
G_gallus_ENSGALP00000021094               YAVGIQQVLLRILD--------QYRQKD-YVAPR----------VLQQTLNYLNQGVIHSVTWKQM---KPHI-QSITEEVIFSL---MCYKDEDEELWQEDPYEYIRMKFDVFEDYAST
T_guttata_ENSTGUP00000011802              YAVGIQQVLLRILD--------QYRQKD-YVAPR----------VLQQTLNYLNQGVIHSITWKQM---KPHI-QTITEEVIFSL---MCYKDEDEELWQEDPYEYIRMKFDVFEDYAST
S_cerevisiae_YJR132W                      FLTQFLQVVFDQIE--------KWGTGQLWLSDE----------CLYYILNFVEQCVVQKTTWKLV---GPHY-NVILQHVIFPL---LKPTAETLEAFDNDPQEYINRNMDFWDVGYSP
A_aegypti_AAEL004441-PA                   ILPPIWQLLTQMADIYIKIVVNETEENP-FVSNSDGDEGDDFTAMILQTFEFLHT-IIEMKKY------KGAV-TNVLTDLIYIVILYMQMTEEQVQSWHDDPEKFVEDEDEQGIDF-TI

                                                  490       500       510       520       530       540       550       560       570       580       590       600
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000262982                 RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHILPDLKSAN-VNEFPVLKADGIKYIMIF
M_mulatta_ENSMMUP00000025796              RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHILPDLKSAN-VNEFPVLKADGIKYIMIF
P_pygmaeus_ENSPPYP00000012414             RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHILPDLKSAN-VNEFPVLKADGIKYIMIF
P_troglodytes_ENSPTRP00000023391          RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHILPDLKSAN-VNEFPVLKADGIKYIMIF
B_taurus_ENSBTAP00000047927               RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHILPDLKSAN-VNEFPVLKADGIKYIMIF
E_caballus_ENSECAP00000013844             RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVSHILPDLKSAN-VNEFPVLKADGIKYIMIF
C_familiaris_ENSCAFP00000016619           RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHILPDLKSANVVNEFPVLKADGIKYIMIF
M_musculus_ENSMUSP00000002790             RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHILPDLKSNN-VNEFPVLKADGIKYIMIF
R_norvegicus_ENSRNOP00000010210           RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHILPDLKSNN-VNEFPVLKADGIKYIMIF
M_domestica_ENSMODP00000020339            RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--RHGITQANELVNLTEFFVNHIQPDLKSAN-VNEFPVLKADGIKYIMIF
O_anatinus_ENSOANP00000010219             RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--RHGITQANELVNLTEFFVNHIQPDLKSTN-VNEFPVLKADGIKYIMIF
T_guttata_ENSTGUP00000009114              RRAACDLVRGLC-FFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHIQPDLKSAT-VNEFPVLKADGIKYIMIF
G_gallus_ENSGALP00000007487               RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHIQPDLKSAS-VNEFPVLKADGIKYIMIF
X_tropicalis_ENSXETP00000003710           RRAACDLVRGLCKFFEGPVTNIFSGYVSSMLQEYAKSPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNITEFFVNHILPDLKSAN-INEYPVLKADGIKYIMFF
G_aculeatus_ENSGACP00000001261            RRAACDLVRGLCKFFEGPVTAIFSGYVSSMLGEYAKNPGENW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLNEFFVNHILSDLKSPN-VNEFPVLKADAIKYVMIF
T_nigroviridis_ENSTNIP00000017660         RRAACDLVRGLCKFFEGPVTAIFSGYVNSMLAEYAKNPGQNW--------KHKDAAIYLVTSLASKGQTQ--KHGITQANQLVNLNEFFVNHILTDLKSPN-INEFPVLKADAIKYVMIF
O_latipes_ENSORLP00000000743              RRAACDLVRCLCKFFEGPVTAIFSGYVNSMLGEYAKSPKENW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANEMVNLIEFFVNHILPDLKSSN-VNEFPVLKADAIKYVMIF
D_rerio_ENSDARP00000022858                RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLAEYAKNPGVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLSEFFLNHILIDLKSPN-VNEFPVLKSDAIKYVMTF
T_rubripes_ENSTRUP00000013203             RRAACDLVRGLCKFFEEPVTAIFSGYVNSMLTEYAKNPGQNW--------KHKDAAIYLVTSLASKGQTQ--KHGITQANQLVNLNEFFVNHILTDLKSPN-VNEFPVLKADAIKYVMIF
O_cuniculus_ENSOCUP00000004737            RRAACDLVRGLCKFFERPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHILPDLKSAN-VNEFPVLKADGIKYIMIF
G_gorilla_ENSGGOP00000010615              RRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--K------------------------------NEFPVLKADGIKYIMIF
A_carolinensis_ENSACAP00000015734         RRAACDLVRGLCRFFEGPVTGIFSGYVNSMLQEYAKNPSVNW--------KHKDAAIYLVTSLASKAQTQ--KHGITQANELVNLTEFFVNHILPDLKSPN-VNEFPVLKADGIKYIMIF
C_intestinalis_ENSCINP00000004657         RRAACDLVKGLTKFFEAPVTQIFSQYVASMLQQYASNPAVNW--------KSKDAAIYLVTSLAQKGSTA--KHGTTQANQLVNLDEFFTSHILTDLNQEN-VNNLPVLKSDSIRFVVTF
A_gambiae_AGAP010711-PA                   RRAACDLVKSLLQKFEAKIVEIFGQYLQVLLAKYAENPAANW--------KAKDTAIYLVTSMASKGQTQ--KLGVTQTSELVPLPQFTQQQIIPELERAD-VNQLPVLKADALKFIMTF
A_aegypti_AAEL008741-PA                   RRAACDLVKTLSQNFESKIIEIFGQYLQVLLAKYAENPANNW--------KTKDTAIYLVTSMASKGQTQ--KLGVTQTSELVPLPQFTQQQIIPELERAD-VNELPVLKADALKFIMTF
D_melanogaster_FBpp0080484                RRAACDLVKTLSINFEQKIFGIFGQYLERLLTKYKENPATNW--------RSKDTAIYLVTSWASRGGTQ--KHGITQTSELVPLPEFCAQQIIPELERPN-INEFPVLKAAAIKYVMVF
S_cerevisiae_YGL238W                      RRACTDFLKELKEKNEVLVTNIFLAHMKGFVDQYMSDPSKNW--------KFKDLYIYLFTALAINGNIT--NAGVSSTNNLLNVVDFFTKEIAPDLTSNN-IPHI-ILRVDAIKYIYTF
C_elegans_Y48G1A.5                        RRGAIDLARGLCRRFEAQMLPCLGEIVQNLLG------SGDW--------IKIDIVYSLITAIAVKTETA--KSGVTATNPLVDINDFFITQVATHLN-AD-VNQTPILKADALKFAVTF
D_melanogaster_FBpp0076408                VPAAQSLLHSMCKKR-KGILPKAMATIMQIIT----SPNADN--------KQKDGALHMIGTLADVLL-K--KASYRDQVES-----MLTTYVFPEF-----QNPAGHMRARACWVLHYF
B_taurus_ENSBTAP00000039739               TTAAQTLLFTACSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
H_sapiens_ENSP00000369042                 TTAAQTLLFTACSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
C_familiaris_ENSCAFP00000010873           TTAAQTLLFTACSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
M_musculus_ENSMUSP00000081782             TTAAQTLLFTACSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
P_troglodytes_ENSPTRP00000048248          TTAAQTLLFTACSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
M_musculus_ENSMUSP00000046759             TTAAQTLLYTAAKKR-KEVLPKMMAFCYQILT----DPNFDP--------RKKDGALHVIGSLAEILL-K--KSLFKDQIEL-----FLQNHVFPLL-----MSNLGYLRARSCWVLHAF
R_norvegicus_ENSRNOP00000014004           TTAAQTLLFTACSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
C_intestinalis_ENSCINP00000017536         ASAAQHLLHSAASKR-KQVLQKTMGFCYSVLT----DAATSEELI-----RRRDGALHIIGSLADTLL-K--RKMYKDQLEL-----MLRTHVIPEL-----QSDYGFMRARACWVVQHF
X_tropicalis_ENSXETP00000052227           TTAAQTLLFTSCSKR-KEVLQKTMGFCYQILT----EPAADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEF-----MLQNHVFTLF-----SSELGYMRARACWVLHYF
O_latipes_ENSORLP00000008906              TTAAQTLLFTACNKR-KEVLQKTMGFCYQILT----DPNSDP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEF-----MLQNHVFPLF-----RSELGYMRARACWVLHYF
O_cuniculus_ENSOCUP00000006136            XXXXXXXXXXXXXXX-XXXXXXXXXXXXXXXX----XXXXXX--------XXXXXXXXXXXXXXXXXX-X--XXXXXDQMEY-----MLQNHVFPLF-----SSDLGYMRARACWVLHYF
D_rerio_ENSDARP00000051878                ATAAQTLLFTACNKR-KEVLQKSMGFCYQILT----DPATDP--------RKKDGALHMIGSLAEILL-K--RKIYKDQMEF-----MLQNHVFPLF-----RSELGYMRARACWVLHYF
G_aculeatus_ENSGACP00000020688            TTAAQTLLFTACNKR-KEVLQKTMGFCYQILT----DPATDP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEF-----MLQNHVFPLF-----RSELGYMRARACWVLHYF
A_carolinensis_ENSACAP00000009310         TTAAQTLLFIACGKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
H_sapiens_ENSP00000256079                 TTAAQTLLYTAAKKR-KEVLPKMMAFCYQILT----DPNFDP--------RKKDGALHVIGSLAEILL-K--KSLFKDQMEL-----FLQNHVFPLL-----LSNLGYLRARSCWVLHAF
M_mulatta_ENSMMUP00000001816              TTAAQTLLYTAAKKR-KEVLPKMMAFCYQILT----DPNFDP--------RKKDGALHVIGSLAEILL-K--KSLFKDQMEL-----FLQNHVFPLL-----LSNLGYLRARSCWVLHAF
P_troglodytes_ENSPTRP00000008198          TTAAQTLLYTAAKKR-KEVLPKMMAFCYQILT----DPNFDP--------RKKDGALHVIGSLAEILL-K--KSLFKDQMEL-----FLQNHVFPLL-----LSNLGYLRARSCWVLHAF
P_pygmaeus_ENSPPYP00000005014             TTAAQTLLYTAAKKR-KEVLPKMMAFCYQILT----DPNFDP--------RKKDGALHVIGSLAEILL-K--KSLFKDQMEL-----FLQNHVFPLL-----LSNLGYLRARSCWVLHAF
C_familiaris_ENSCAFP00000015868           TTAAQTLLYTAAKKR-KEVLPKMMAFVYQILT----DPNFDP--------RKKDGALHVIGSLADILL-K--KSLFKDQMEL-----LLQNHVFPLL-----LSNLGYLRARSCWVLHAF
E_caballus_ENSECAP00000014130             TTAAQTLLFTACSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
B_taurus_ENSBTAP00000018760               TTAAQTLLYTAAKKR-KEVLPKMMAFCYQILT----DPNFDP--------RKKDGALHVIGSLADILL-K--KSLFKDQMEL-----LLQNHVFPLL-----LSNLGYLRARSCWVLHAF
T_nigroviridis_ENSTNIP00000012237         TTAAQTLLFTACNKR-KEVLLKTMGFCYHILT----DQTCDP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEL-----MLQNHVFPLF-----RSELGYMRARACWVLHYF
E_caballus_ENSECAP00000011294             TTAAQTLLYTAAKKR-KEVLPKMMAFCYQILT----DPNFDP--------RKKDGALHVIGSLADILL-K--KSLFKDQMEL-----LLQNHVFPLL-----LSNLGYLRARSCWVLHTF
O_anatinus_ENSOANP00000009316             TTAAQTLLFTACSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
G_gallus_ENSGALP00000009312               TTAAQTLLFTSCSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
T_guttata_ENSTGUP00000008467              TTAAQTLLFTSCSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSELGYMRARACWVLHYF
A_carolinensis_ENSACAP00000012797         STAAQLLLYTAAKKR-KEVLPKMMAFCYQILT----EPNVDP--------RKKDGALHVIGSLADILL-K--KSVFKDQMEL-----MLQNHVFPLF-----MSNLGYLRARSCWTLHSF
M_domestica_ENSMODP00000009743            TTAAQTLLFTACSKR-KEVLQKTMGFCYQILT----EPNADP--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEY-----MLQNHVFPLF-----SSDLGYMRARACWVLHYF
T_rubripes_ENSTRUP00000032909             ASAAQGLLHKAARKR-KEVLPQMMDFCHQVLV----DPCADP--------HRKDGALHCIGTLAEVLM-K--KRLYREEMEL-----MLQNYVFPLL-----NSPLGYLRARSCWVLHCF
G_aculeatus_ENSGACP00000025426            ATAAQGVLYKAARKR-KQVLPQMMEFCHQILV----DPSPDP--------RKKDGALHCIGALADLLL-K--KRMYREQMEL-----MLQNYVFPLL-----NSPMGYLRARSCWVLHCF
O_latipes_ENSORLP00000015709              VTAAQSLLCKAARKR-RQVLPQMMEFCHHTLM----DPSADP--------RRQDGALHCIGVLADLLL-K--KQVYREQMEL-----MLQNYVFPLL-----NSPSCYLRARSCWMLHCF
T_rubripes_ENSTRUP00000044627             TTAAQTLLFTSCNKR-KEVLQKTMGFCYQILI----DPACDA--------RKKDGALHMIGSLAEILL-K--KKIYKDQMEL-----MLQAHVFPLF-----TNALGYMRARACWVLHYF
T_nigroviridis_ENSTNIP00000010026         ASAAQGLLYKAARKR-KEVLPQMMEFCHKILV----DPCADP--------HRKDGALHCIGTLAELLL-K--KRIYREQMEL-----ILQTYVFPLL-----GSPLGYLRARSCWLLHCF
D_rerio_ENSDARP00000024402                ATAAQTLLCTAARKR-KEVLPQMMEFCHQILV----DPSADP--------RRTDGALHVIGTLAQPLL-K--KRVYRDQMEL-----MLQNYVFPLL-----NSNLAYLRARSCWVLHSF
G_gallus_ENSGALP00000021094               TTAAQNLLYTAAKKR-KEVLPKMMAYCYQILT----EPNIDP--------RKKDGALHVIGSLADILL-KQQKSVFKDQMEL-----MLQNHVFPLF-----MSNLGYLRARSCWVIHSF
T_guttata_ENSTGUP00000011802              TTAAQNLLYTAAKKR-KEVLPKMMAYCYQILT----EPNIDP--------RKKDGALHVIGSLADILL-KQQKSVFKDQMEL-----MLQNHVFPLF-----MSNLGYLRARSCWVLHSF
S_cerevisiae_YJR132W                      DLAALALLTTCVTKRGKTTLQPTLEFMVSTLQ----SAVGDYNNIMLDNALQIESCLRIFSSIIDRLITK--DSPFASEMEK-----FILTYVLPFF-----KSQYGFLQSRVCDICSKL
A_aegypti_AAEL004441-PA                   RSTVTDVLLIIGQEYEQKLLPCLSEALSKHIA----VADADRNAGNPHWWKVYEASMLAVGSFKDLIVENEGKFDMAQYMNLVKN--TMEYQVSP------------YLLGRCLWIFSRY

                                                  610       620       630       640       650       660       670       680       690       700       710       720
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000262982                 RNQV--PKEHLLV---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGPNNAT--LFTAAEIAPFVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
M_mulatta_ENSMMUP00000025796              RNQV--PKEHLLV---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGPNNAT--LFTAAEIAPFVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
P_pygmaeus_ENSPPYP00000012414             RNQV--PKEHLLV---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGPNNAT--LFTAAEIAPFVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
P_troglodytes_ENSPTRP00000023391          RNQV--PKEHLLV---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGPNNAT--LFTAAEIAPFVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
B_taurus_ENSBTAP00000047927               RNQV--PKEHLLV---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGPNSAT--LFTAAEIAPFVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
E_caballus_ENSECAP00000013844             RNQV--PKEHLLV---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGPNNAT--LFTAAEIAPFVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
C_familiaris_ENSCAFP00000016619           RNQV--PKEHLLV---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGPNNAT--LFTAAEIAPFVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
M_musculus_ENSMUSP00000002790             RNQV--PKEHLLV---SIPLLISHLE--AESIVVHTYAAHALERLFTMRGSNNTT--LFTAAEIAPFVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
R_norvegicus_ENSRNOP00000010210           RNQV--PKEHLLV---SIPLLISHLG--AESIVVHTYAAHALERLFTMRGPNNAT--LFTAAEIAPFVGILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
M_domestica_ENSMODP00000020339            RNQV--PKEQLLA---SIPLLINHLQ--AESIVVHTYAAHALERLFTMKGSNNTI--LITAAEIAPFVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
O_anatinus_ENSOANP00000010219             RNQV--PKEQLLV---SIPLLISHLQ--AESIVVHTYAAHALERLFTMRGSNNTT--LITAAEMVPFVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
T_guttata_ENSTGUP00000009114              RNQV--PKEQLLV---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGTNNAT--LITAAEMAPFVEVLLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQESIIPYIPSV
G_gallus_ENSGALP00000007487               RNQV--PKEQLLL---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGTNNTT--LITAAEMAPFVEVLLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQESIIPYIPSV
X_tropicalis_ENSXETP00000003710           RSQL--PKEQLLV---TIPLLIAHLQ--AESVVVHTYAAHALERFFTMKGATSPT--LIVAAEMMPYVELLLANLFKALSLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPSV
G_aculeatus_ENSGACP00000001261            RSQL--PKEQLLQ---AVPLLISHLQ--AESTVEHTYSAHALERLFTMRGPNNTT--LITPAEMAPFTEQLLNNLFKALALPGSA-----ENE-YIMK--AIMRSFSLLQESIVPYIPTL
T_nigroviridis_ENSTNIP00000017660         RSQL--PKEHLLQ---AVPLLINHLQ--AESSVEHTYAAHALERLFTMRGPNNTT--LITPAEMAPFTEQLLTNLFKALALPGST-----ENE-YIMK--AIMRSFSLLQESIIPYIPTL
O_latipes_ENSORLP00000000743              RSQL--PKEHLLQ---AVPLLITHLQ--AESTVQHTYAAHALERLFTMKGPSNLT--LISSAEMAPYIEQLLTNLFKALTLPGSA-----ENE-YIMKGEAIMRSFSLLQETIVPYIPTL
D_rerio_ENSDARP00000022858                RSQL--PKEQLLQ---AVPLLVSHLQ--AESIVQHTYAAHALERLFTMRGGNNTT--LITPTEMAPFTEQLLNHLFKALAIPGSS-----ENE-YIMK--AIMRSFSLLQEAIVPYIPTL
T_rubripes_ENSTRUP00000013203             RSQL--PKEHLLQ---AVPLLINHLQ--AESTVEHTYAAHALERLFTMRGPSNTT--LISPAEMAPFTEQLLTNLFKALALPGSA-----ENE-YIMK--AIMRSFSLLQDSIVPYIPTL
O_cuniculus_ENSOCUP00000004737            RNQV--PKEHLLV---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGPNSAT--LFTAAEIAPFVEVLLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPTL
G_gorilla_ENSGGOP00000010615              RNQV--PKEHLLV---SIPLLINHLQ--AESIVVHTYAAHALERLFTMRGPNNAT--LFTAAEIAPFVEILLTNLFKALTLPGSS-----ENE-YIMK--XXXXXXXXXXXXXXXXXXXX
A_carolinensis_ENSACAP00000015734         RNQV--PKEQLLV---SIPLLINHLQ--AESIVVQTYAAHALERLFTMKGANNTT--LITPAEMAPYVEILLTNLFKALTLPGSS-----ENE-YIMK--AIMRSFSLLQEAIIPYIPSL
C_intestinalis_ENSCINP00000004657         RNQL--GKPNLLL---VFPHLTRLLT--STSHVVHTYAAHAIERLLMIKDGNVPL--RFRKEDVHPHLESLLSNIFGAMSMAGSE-----ENE-YMMK--ALLRIASLSQETILPYMPTL
A_gambiae_AGAP010711-PA                   RTIL--GPQIIVA---TMPLVSKHLG--AASVVVHTYAACAIDKILTMRGPDKQP--IVTKEILSPLSAELIAGLFAAITVQGSN-----ENE-YIMK--CIMRVLNTLQEASLPFMIVV
A_aegypti_AAEL008741-PA                   RTIL--GPQIIVA---TLPLVAKHLA--AGNVVVHSYAACAIDKILTMKGPDNKP--IVTKEILAPLSAELITGLFAAFTVQGSN-----ENE-YIMK--CIMRTLNTLQEASLPFMIVV
D_melanogaster_FBpp0080484                RSIL--GPQVLAS---CLPQLIRHLP--AESSVVHSYAACSVEKILSMRDASNAI--VFGPQILAPYTTELISGLFATLSLPGSG-----ENE-YVMK--AIMRSFSVLQSAAMPFMGVA
S_cerevisiae_YGL238W                      RNQL--TKAQLIE---LMPILATFLQ--TDEYVVYTYAAITIEKILTIRESNTSPAFIFHKEDISNSTEILLKNLIALILKHGSSPEKLAENE-FLMR--SIFRVLQTSEDSIQPLFPQL
C_elegans_Y48G1A.5                        RKQL--APEHLMT---AIKSADALLS--SNTPILHKYAAYAIEKILL---ADSNK--IFSAQNLP--VSSILQNLVTAFDKDAKA-----QNSPYLIK--AILRIIVILDDDTIRHADAI
D_melanogaster_FBpp0076408                CDVQIKNPQVLAE---IMRLTTNALLT-DKELPVKVEAAIGLQMFISSQDE--------APQYVEAQIKEITKEL---LTIIRET-----ENE-DLTN--VMQKIVCTFTEQLLPVATEI
B_taurus_ENSBTAP00000039739               CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
H_sapiens_ENSP00000369042                 CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
C_familiaris_ENSCAFP00000010873           CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
M_musculus_ENSMUSP00000081782             CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
P_troglodytes_ENSPTRP00000048248          CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
M_musculus_ENSMUSP00000046759             SSLKFHNELNLRN---AVELAKKSLIE-DEEMPVKVEAALALQSLISNQAQ--------AKEHMKPYVRFIMQEL---LHIVRET-----END-DVTN--VIQKLICEYSQDVASIAVDT
R_norvegicus_ENSRNOP00000014004           CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
C_intestinalis_ENSCINP00000017536         SEAKFKKKENIIA---TAEALKHLLLN-DGDLPVRVEAAMALQEFLSEQEI--------AEKHCVQHVRPIMQAL---LQLVHET-----END-DLTS--IVQKVICLYCEHVIPYAVEI
X_tropicalis_ENSXETP00000052227           CEVKFKIDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQEK--------AKEYIAPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
O_latipes_ENSORLP00000008906              CEVKFKSDQNLQT---ALELTRLCLIN-DNEMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIVRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
O_cuniculus_ENSOCUP00000006136            CEVKFKSDQNLQM---ALELTRR-------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000051878                CEVKFKNDQNLQV---ALELTRNCLIN-DNELPVKVEAAIALQVLVSNQEK--------AKDYITPHIRPVMQAL---LQIVRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
G_aculeatus_ENSGACP00000020688            CEVKFKSDQNLQT---ALELTRLCLIN-DNEMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIVRET-----END-DLTN--VIQKMICEYSEEVTP-AVEM
A_carolinensis_ENSACAP00000009310         CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQER--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
H_sapiens_ENSP00000256079                 SSLKFHNELNLRN---AVELAKKSLIE-DKEMPVKVEAALALQSLISNQIQ--------AKEYMKPHVRPIMQEL---LHIVRET-----END-DVTN--VIQKMICEYSQEVASIAVDM
M_mulatta_ENSMMUP00000001816              SSLKFHNELNLRN---AVELAKKSLIE-DKEMPVKVEAALALQSLISNQIQ--------AKEYMKPHVRPIMQEL---LHIVRET-----END-DVTN--VIQKMICEYSQEVASIAVDM
P_troglodytes_ENSPTRP00000008198          SSLKFHNELNLRN---AVELAKKSLIE-DKEMPVKVEAALALQSLISNQIQ--------AKEYMKPHVRPIMQEL---LHIVRET-----END-DVTN--VIQKMICEYSQEVASIAVDM
P_pygmaeus_ENSPPYP00000005014             SSLKFHNELNLRN---AVELAKKSLIE-DKEMPVKVEAALALQSLISNQIQ--------AKEYMKPHVRPIMQEL---LHIVRET-----END-DVTN--VIQKMICEYSQEVASIAVDM
C_familiaris_ENSCAFP00000015868           SSLKFHNELNLRN---AVELAKKSLIE-DKEMPVKVEAALALQSLISNQTQ--------AKEYMKPHVRPIMQEL---LHIVRET-----END-DVTN--VIQKMICEYSQEVASIAVDM
E_caballus_ENSECAP00000014130             CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
B_taurus_ENSBTAP00000018760               SSLKFHNELNLRN---AVDLAKKSLIE-DKEMPVKVEAALALQSLISNQTQ------ALAKEYMKPHVRPIMQEL---LHIVRET-----END-DVTN--VIQKMICEYSQEVASIAVDM
T_nigroviridis_ENSTNIP00000012237         CEVKFKSDQNLQT---ALELTRLCLIN-DNEMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIVRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
E_caballus_ENSECAP00000011294             SSLKFHNELNLRN---AVELAKKSLIE-DKEMPVKVEAALALQSLISNQTQ--------AKEYMKPHVRPIMQEL---LHIVRET-----END-DVTN--VIQKMICEYSQEVASIAVDM
O_anatinus_ENSOANP00000009316             CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQLA--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
G_gallus_ENSGALP00000009312               CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKMICEYSEEVTPIAVEM
T_guttata_ENSTGUP00000008467              CEVKFKSDQNLQT---ALELTRRCLID-DREMPVKVEAAIALQVLISNQEK--------AKEYITPFIRPVMQAL---LHIIRET-----END-DLTN--VIQKM