10        20        30        40        50        60        70        80        90       100       110       120
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000347741                 ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000041705          ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004373             ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000012893              ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000027820               ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000007279          -------------------------------------------------------------------------AVPRVEGVFIFLIEDSGKKKRRKNFEAMFKGILQSGLDNLVINHMLK
H_sapiens_ENSP00000376849                 -------------------------------------------------------------------------AVPRVEGVFIFLIEDSGKKKRRKNFEAMFKGILQSGLDNFVINHMLK
P_pygmaeus_ENSPPYP00000004374             -------------------------------------------------------------------------AVPIVEGVFIFLIEDSCKKKRRKNFEAVFKCILQSGLDNLVINHMLK
G_gorilla_ENSGGOP00000015374              ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000010831             ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000012894              ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000031565           -------------------------------------------------------------------------------------------------------MYSSRQQHGLSLEHILK
M_musculus_ENSMUSP00000027012             ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000058685           ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000027009             ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000029448           ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000059619          ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000260309                 ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000006810             ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004377             ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000021890             ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000034022            ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000034033            ------------------------------------------------------------------------------------------------------------------------
O_anatinus_ENSOANP00000016591             ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000027821               ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000034020            ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000000956            ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000021744              ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000021904           ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000004372             ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000027015             ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000047678          ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000009993           ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000364878                 ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000012901              ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000006490            ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000001569               ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000017024           ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000013201            ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000013361         ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000034228                ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000019853             ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000035020             ------------------------------------------------------------------------------------------------------------------------
O_latipes_ENSORLP00000007938              ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000013027             ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000059407                ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000068268                ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000008601                ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000015203           ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000029853               ------------------------------------------------------------------------------------------------------------------------
G_gorilla_ENSGGOP00000011776              ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000006831         ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000031895             ------------------------------------------------------------------------------------------------------------MAAPSGRSQSSL
R_norvegicus_ENSRNOP00000022672           ------------------------------------------------------------------------------------------------------------MAASSGRSQSSL
E_caballus_ENSECAP00000003321             ------------------------------------------------------------------------------------------------------------MAAPSAPSLPAL
P_pygmaeus_ENSPPYP00000020323             ------------------------------------------------------------------------------------------------------------MAAPTAGSWSTF
O_anatinus_ENSOANP00000005545             ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000013612              ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000312664                 ------------------------------------------------------------------------------------------------------------MAAPSAGSWSTF
P_troglodytes_ENSPTRP00000033921          ------------------------------------------------------------------------------------------------------------MAAPSAGSWSTF
M_mulatta_ENSMMUP00000016588              ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000024166               ------------------------------------------------------------------------------------------------------------MAAPSAGFQYPL
C_familiaris_ENSCAFP00000005409           ------------------------------------------------------------------------------------------------------------MAAASAGRPAAL
O_latipes_ENSORLP00000015114              ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000001598            ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000013740            ------------------------------------------------------------------------------------------------------------------------
C_elegans_C48D1.2                         ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000091238             ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000010874         ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000035938           ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000017020             ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000054330          ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000311032                 ------------------------------------------------------------------------------------------------------------------------
O_anatinus_ENSOANP00000015596             ------------------------------------------------------------------------------------------------------------------------
O_anatinus_ENSOANP00000000517             ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000019797             ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075318                ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000015808              ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000004412            ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000003205               ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000005560            ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000014096           ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000083664                ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000040691             ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002956         ------------------------------------------------------------------------------------------------------------------------
O_latipes_ENSORLP00000010095              ------------------------------------------------------------------------------------------------------------------------
A_aegypti_AAEL003444-PA                   ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000032189           ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000009934         ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000017449              ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000009923         ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024812            ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000005556            ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024816            ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024809            ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000008661            ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000002083               ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000006879              ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000019984                ------------------------------------------------------------------------------------------------------------------------
T_nigroviridis_ENSTNIP00000022078         ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP000830-PA                   ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000015102             ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000011206              ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000017288               ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000006831                ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000036247            MDFHTFLYGIAEEIDSADLASLKFLCLDQIPLKKQQHIKDALVLFQTLEERGLLEEDNLFFLKELLFRINRIDLLNEPLNTKGPEMERELQVPNKARISPYRLHLHTTIWPFRDNWTCRI
T_rubripes_ENSTRUP00000031759             ------------------------------------------------------------------------------------------------------------------------
D_melanogaster_FBpp0084848                ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000022402            ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP011951-PA                   ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000023986           ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000056642          --------------------------------------------------------------------------------------------------------RGGRPWGGGGSWGLGR
B_taurus_ENSBTAP00000021099               ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000030747             ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000063081                ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000003217           ------------------------------------------------------------------------------------------------------------------------
O_latipes_ENSORLP00000010793              ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000002138             ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000017972           ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000010379             ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000072390                ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000365051                 --------------------------------------------------------------------------------------------------------RGGRPWGGGGSWGLGR
D_rerio_ENSDARP00000047019                ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000002670         ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000013731             ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000014503               ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP009832-PA                   ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000040583              ------------------------------------------------------------------------------------------------------------------------
O_anatinus_ENSOANP00000019254             ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000023821           ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000018104            ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000012869               -----------------------------------------------------------------------------------------------------------------------M
B_taurus_ENSBTAP00000008706               ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075645                ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP004920-PA                   ------------------------------------------------------------------------------------------------------------------------
D_melanogaster_FBpp0071971                ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000007379            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000024485         ---------------------------------------EFRLLLHQICEGLTGENVSMMKFLCKDAIPRSRELETALDFMEYFEAKGWIQEGDLGFLAEVLYRINRHDLLKLLPGVKNR
A_carolinensis_ENSACAP00000013788         ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000045375             ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000071815                ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000002346            ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000028116               ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000221740                 ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000044662             ----------------------------------------CNMDFQARLLKVGNDLRKDEVRALVFLCSDILGCNPAAVQSAGDLFSRLSDQDHLSEEQPHLLVELLGIIQRTKLLRDHN
O_latipes_ENSORLP00000003208              ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075650                ------------------------------------------------------------------------------------------------------------------------
T_guttata_ENSTGUP00000010625              -DFRKLLFEVSEALVTEELSALKFLSLDHVPRRKLEAIHEPKAFFEVLQEKDMIGAGNLFFLKELLYRIHRIDLLSTPLGCSREEMERELQLPGRAQVSAYR------------------
A_aegypti_AAEL014348-PA                   ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000026062             ------------------------------------------------------------------------------------------------------------------------

                                                  130       140       150       160       170       180       190       200       210       220       230       240
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000347741                 ----------------------MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQN-VLNWKEE----------------EKKKYYDAKTEDKVRVMADSMQEKQRMAGQMLLQTFF--NI
P_troglodytes_ENSPTRP00000041705          ----------------------MAEGNHRKKPLKMLESLGKDFLTGVLDNLVEQN-VLNWKEE----------------EKKKYYDAKTEDKVRVMADSIQEKQRMAGQMLLQTFF--NI
P_pygmaeus_ENSPPYP00000004373             ----------------------MAEGNHRKKPLKMLESLGKDFLTGVLDNLVEQN-VLNWKEE----------------EKKKYYDAKTEDKVRVMADSIQEKQRMAGQMLLQTFF--NI
M_mulatta_ENSMMUP00000012893              -----------------------------------------------------------------------------------------------MADSIQEKQRMAGQMLLQTFF--NI
B_taurus_ENSBTAP00000027820               ----------------------MAEDKHNKNPLKMLESLGKELISGLLDDFVEKN-VLKLEEE----------------EKKKIYDAKLQDKARVLVDSIRQKNQEAGQVFVQTFL--NI
P_troglodytes_ENSPTRP00000007279          NNVAGQTSIQTLVPNTDQKSTSVKKDNHKKKTVKMLEYLGKDVLHGVFNYLAKHD-VLTLKEE----------------EKKKYYDAKIEDKALILVDSLR-KNRVAHQMFTQTLL--NM
H_sapiens_ENSP00000376849                 NNVAGQTSIQTLVPNTDQKSTSVKKDNHKKKTVKMLEYLGKDVLHGVFNYLAKHD-VLTLKEE----------------EKKKYYDTKIEDKALILVDSLR-KNRVAHQMFTQTLL--NM
P_pygmaeus_ENSPPYP00000004374             NNVAGQTSIQTL-PNTDQKSTSVKKDNHKKKTIKMLEYLGKDVLHGVFNHLAKHD-VVTLKEE----------------EKKKYYNAKIEDKALILVDSVR-KNRVAHQIFIQTLL--DM
G_gorilla_ENSGGOP00000015374              -------------------------DNHKKKTVKMLEYLGKDVLHGVFNYLAKHD-VLTLKEE----------------EKKKYYDAKIEDKALILVDSXR-KKRVAHQMFTQTLL--NM
E_caballus_ENSECAP00000010831             ----------------------MAEDRQERNLLKTLESVGKELITGLSVGLVEKD-VLKLKEE----------------ERKKFYEAKPGDKPWVLVDSVRDRRHEAGQILWQALF--NI
M_mulatta_ENSMMUP00000012894              ------------------------------------------MLHGVFNHLAKHD-VLTLNEE----------------EKENYYNVKIEDKALILVDSVR-KNRVAHQRFTQTLL--NM
C_familiaris_ENSCAFP00000031565           NGEIARDGKTYVVPIVEGVFVFLTEDKHDKNPFKILETVGKELITGVLHGLLEKD-ILKLEDA----------------EKKTFYDAKPEDKPWVILNSVRQKRQEAGQALVHTFI--NT
M_musculus_ENSMUSP00000027012             ----------------------MAENKHPDKPLKVLEQLGKEVLTEYLEKLVQSN-VLKLKEE----------------DKQKFNNAERSDKRWVFVDAMKKKHSKVGEMLLQTFF--SV
R_norvegicus_ENSRNOP00000058685           ----------------------LTENNHPDKPLKVLEELGKEFLTEYLEKLVQSN-VLKLKEE----------------EKQKFNNAERSDKRWVFVDVLKRKHNQVGKMLLQTFL--NV
M_musculus_ENSMUSP00000027009             ---------------------MAARRTHERDPIYKIKGLAKDMLDGVFDDLVEKN-VLNGDEL----------------LKIGESASFILNKAENLVENFLEKTDMAGKIFAGHIA--NS
R_norvegicus_ENSRNOP00000029448           ---------------------FTAKRTHERDPIYKIKGLAKDMLDGVFDDLMDKN-VLNGDEL----------------LKIGEGASLILSKAENLVESFFEKTEMAGKIFAGHIA--NS
P_troglodytes_ENSPTRP00000059619          ----------------------MADKFLKEKRKLFIRSMGEGTINGLLDELLQTR-VLNQEEM----------------EKVKRENATAMDKTRALIDSVIPKGAQACQICITYIC--EE
H_sapiens_ENSP00000260309                 ----------------------MADKVLKEKRKLFIRSMGEGTINGLLDELLQTR-VLNKEEM----------------EKVKRENATVMDKTRALIDSVIPKGAQACQICITYIC--EE
E_caballus_ENSECAP00000006810             ---------------------LAGRGPEKEDPVNLMKSIARNMFEGFLDDL-ENN-VLSRDDL----------------RKLGKRVNRIVNGTENLVEDLSEKTEVAGKIFLKHLL--KP
P_pygmaeus_ENSPPYP00000004377             ----------------------MADKVLKEKRKLFIRSMGEGTINGLLDELLQTR-VLNKEET----------------EKVKRENATVMDKTRALLDSLIPKGARACEICITYIC--EE
E_caballus_ENSECAP00000021890             -----------------------TGNVLKEKRRLFIRSVGTGTVNSLLDELLEKR-VLNQEEM----------------EKVRDENATVMDKARALIDAVIRKGPQACQIFIGHIC--ED
M_domestica_ENSMODP00000034022            ----------------------LTDKVLMEKRRLFVESVDRGVMNGLLDDLLEVQ-VLNLEEM----------------EIVREESKTNRDKARVLIDAVISKGPKASQCFTKSIC--ER
M_domestica_ENSMODP00000034033            ----------------------LTDKVLKEKRRLFVESVDRGVINGLLDDLLELQ-VLNLEEM----------------EILKEESRTIRDKARVLIDAIISKGPKASQCFTKSIW--ER
O_anatinus_ENSOANP00000016591             ----------------------PPAQLLKDRWCLIIESLTHGMISGLLDDLLQMQ-VINQEEM----------------DTVREEHHRPAEKTRALLNSVIPKGDLASQIFIDSLC--KK
B_taurus_ENSBTAP00000027821               -----------------------------EKRKLFVHSVSKGTINGLLDELLEKR-VLNQEEM----------------EKIRDENDTAMDRARVLIDTVIRKGPQACQICISHIC--EE
M_domestica_ENSMODP00000034020            ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000000956            ----------------------MADRILKDRRKRFINSVGTGTINGLLDELLEKR-VLNQEEM----------------EKVRVENATVMDKARALLDCVIRKGPQACQICINHIC--ED
M_mulatta_ENSMMUP00000021744              ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000021904           ---------------------VLTGKRQSQDPVNAIKVVASTMLNSFLEDLKEKN-VLNKQEL----------------QTMGQTVNVITKKTENLVGDLTEKTQVVGKIFKDHFL--NS
P_pygmaeus_ENSPPYP00000004372             ---------------------FTDEKPSNGVPVHMVKLLIRTFLDGIFDDLMENN-VLNTDEI----------------HLIGTCLKFVVSNAENLVDDITQTAQIAGKIFREHLW--NS
M_musculus_ENSMUSP00000027015             ----------------------MADKILRAKRKQFINSVSIGTINGLLDELLEKR-VLNQEEM----------------DKIKLANITAMDKARDLCDHVSKKGPQASQIFITYIC--NE
P_troglodytes_ENSPTRP00000047678          ---------------------MADEKPSNGVLVHMVKLLIKTFLDGIFDDLMENN-VLNTDEI----------------HLIGKCLKFVVSNAENLVDDITETAQIAGKIFREHLW--NS
R_norvegicus_ENSRNOP00000009993           ----------------------MADKILRAKRKQFINSVSVGTINGLLDELLEKR-VLNQEEM----------------DTIKLANITVMEKARDLCDHVTKKGPRASQMFITYIC--NE
H_sapiens_ENSP00000364878                 ---------------------MADEKPSNGVLVHMVKLLIKTFLDGIFDDLMENN-VLNTDEI----------------HLIGKCLKFVVSNAENLVDDITETAQTAGKIFREHLW--NS
M_mulatta_ENSMMUP00000012901              -----------------------TDKVLKEKRKLFIHSMGE-------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000006490            ----------------------------YKDVLKEMESAGKAIAGSFMDNLVKKK-VIKLEKA----------------KREKFYDAKTHKKAQILVDSLREKCHEEDQKLTETFL--NI
G_gallus_ENSGALP00000001569               ---------------------------LLRVRADFVSRVRKAVVSNLLDELLAHR-VLNQAEV----------------DEVQEGNPVTTDKARSLIDTVRLKGPRASAIFIDSLR--KH
X_tropicalis_ENSXETP00000017024           -----------------------LAAQLKKVRKLFIDGCNAAIINNLLDDLLDKS-VLTDSEV----------------EYINECNAITKDRCRRMIDNIKNKGDYSSNILLQCLV--EN
G_aculeatus_ENSGACP00000013201            ----------------------YFSDKLKKVRTKFVEKASMSLIKQLLDDLLDNG-ILNDGQK----------------DSILEENGTKADRARNLIDVVKAKGNKASEILIASLE--SR
A_carolinensis_ENSACAP00000013361         ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000034228                -----------------------MAKSIKDHLQDALSNIGADNLRRFQSRLGDRK---------------------QEPRVRKSTIEKLKDEIDLVDLLVNTFTSDAVSVTVDILR--GI
T_rubripes_ENSTRUP00000019853             -----------------------LPDQLASIRPMFVEKVSTQMINQLLDDIFMDG-IVSEMEK----------------ESITEESNIRSDKARRLIDSVRKKGERACKKMISHIQ--SR
T_rubripes_ENSTRUP00000035020             -----------------------MEDKLTSIRLMFVEKVSTQMINQLLDDIFMDG-IVSEMEK----------------ESITEESNIRSDKARRLIDSVRKKGERACKKMISHIQ--SR
O_latipes_ENSORLP00000007938              -------------------------------------------------MLLQDK-VLNDEER----------------ESICEEK-SRADMARSLIDTVRKKGSTASKMMINHFE--QK
T_rubripes_ENSTRUP00000013027             ----------------------MAICQLDSIRLMFVEKVSTQMINQLLDDIFMDG-IVSEMEK----------------ESITEESNIRSDKARRLIDLVRKKGERACKKMISHIQ--SR
D_rerio_ENSDARP00000059407                -----------------------KMEDITKLITDVLEELVESELKEFKRQLW----MGVKKGV----------------EAIPRGKLENKDRQDVVDYMVQHYSMDAGKIAVQALR--SI
D_rerio_ENSDARP00000068268                ------------------------MEDITQLLSDVLEDLVESELKQFTRQLW----IGVKPGV----------------EPIPRGKLENKDRQDVVDSMVQQYSEDAGTITVQTLR--KI
D_rerio_ENSDARP00000008601                -------------MTEEVNWDEDLEVDAVVQNLNLYKTVMRNDKNSNSEVQLSNE-LVDFAVELTCGHRMPVDYVVAWFKCYLKQKETDFSCPHFIVDQGKTCGAKLSYQEICQLIPLSD
X_tropicalis_ENSXETP00000015203           ---------------MLGGMQKHHKDALQRLRVTLLHDMIIEE---LVEHLVSSG-ILTPIMHS-----------------TIMAHRSEYKQNVTLLTQLPKRGPRAFSEFCNALH--AT
G_gallus_ENSGALP00000029853               ---------------GACGMQRYHQEALKKNRVMLARELVLKE---LMEHMIEKD-IITIEMVE-----------------MIQAKSGSFSQNVEFLNLLPKRGPNAFSAFCEALQ--ET
G_gorilla_ENSGGOP00000011776              ---------------------MADEKPSNGVPVHMVKLLIKTFLDGIFDDLMENN-VLNTDEI----------------HLIGKCLKFVLSNAENLVDDITETAQIAGKIFREHLW--NS
A_carolinensis_ENSACAP00000006831         -----------SRMLGVCGMQKCHQEALKKNRVSLAKQLVLKE---LMEHLIEKD-VITEEMME-----------------MIQAKAGNFSQNIEFLNLLPKRGPKAFSAFCEALR--ET
M_musculus_ENSMUSP00000031895             HRKGLMAADRRSRILAVCGMHPDHQETLKKNRVVLAKQLLLSE---LLEHLLEKD-IITLEMRE-----------------LIQAKGGSFSQNVELLNLLPKRGPQAFDAFCEALR--ET
R_norvegicus_ENSRNOP00000022672           HRKGLMAADRRSRILAVCGMHPDHQETLKKNRVVLAKQLLLSE---LLEHLLEKD-IITLEMRE-----------------LIQAKGGSFSQNVELLNLLPKRGPQAFDAFCEALR--ET
E_caballus_ENSECAP00000003321             QQKGLMAADRGRRILGVCGMHPDHQEALKKNRVVLAKQLLLSE---LLEHLLEKD-IITLEMRE-----------------LIQAKVTSFGQNVELLNLLPKRGPQAFEAFCVALR--ET
P_pygmaeus_ENSPPYP00000020323             EHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSE---LLEHLLEKD-IITLEMRE-----------------LIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALR--ET
O_anatinus_ENSOANP00000005545             -------------------MQPCHQEALKKNRVALAKQLMLSE---LLEHLLEKD-VITMEMRE-----------------LIQAKAGSFSQNVEFLNLLPKRGPKAFDAFCAALR--ET
T_guttata_ENSTGUP00000013612              -------------MLAACGMQRCHQEALKKNRVMLAKQLVLNV---LVEHMVEKD-IIPTEMVE-----------------MIQAKSGSFDRNVEFLNLLPKRGPNAFSAFCEALR--ET
H_sapiens_ENSP00000312664                 QHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSE---LLEHLLEKD-IITLEMRE-----------------LIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALR--ET
P_troglodytes_ENSPTRP00000033921          QHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSE---LLEHLLEKD-IITLEMRE-----------------LIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALR--ET
M_mulatta_ENSMMUP00000016588              ------------RILGVCGMHPHHQETLKKNRVMLAKQLLLSE---LLEHLLEKD-IITLEMRE-----------------LIQAKVGSFSQNVELLNLLPKR-PQAFDAFCEALR--ET
B_taurus_ENSBTAP00000024166               QPKEQMAADRGRRMLRGCGMHPDHQEALKKNRVVLAKELLLSE---LLEHLLEKD-IITLEMRE-----------------HIQAKTGSFGQNVELLNLLPKRGPQAFDAFCVALR--ET
C_familiaris_ENSCAFP00000005409           QRKAPTAAGRGRRILGVCGMHPDHQEALKKNRVVLAKQLLLSE---LLEHLLEKD-IITLEMRE-----------------HIQAKVGGFSQNVELLNLLPKRGPQAFDAFCVALR--ET
O_latipes_ENSORLP00000015114              -----------RSVTQKCGMQKRDAEALRNCSVCLLKDLVVDE---LLIQALVKDGILTQNMAE-----------------SIMVQKTSHHRSFKLLLLLPKRGPRAFKSFCSALK--ET
M_domestica_ENSMODP00000001598            ------------RMLGVWGMEQEHQEALKKNRVVLAKQLLLSE---LLEHLLEKD-IITLEMRE-----------------LIQAKVGSFSQNVEFLNLLPKRGPHAFEAFCDALR--ET
G_aculeatus_ENSGACP00000013740            -----------------CGMQERDRLALRTRSTVLCKQLVVDE---LLIQSLQTDEILTEAMAE-----------------NIMAEQTSQKRSWRLLLLLPKRGPRAFSSFCSALQ--ET
C_elegans_C48D1.2                         ------------------MMRQDRRSLLERNIMMFSSHLKVDE---ILEVLIAKQ-VLNSDNGD-----------------MINSCGTVREKRREIVKAVQRRGDVAFDAFYDALR--ST
M_musculus_ENSMUSP00000091238             --------------------------------------------------------------------------------------------MENNKTSVDSKS----------------
T_nigroviridis_ENSTNIP00000010874         --------------MLQCGMVERDAQALKKQSAVLFKQLVVDE---LLIQFLQADDILTDSMAE-----------------SILAEQTSHKRCWKLLHLLPKRGPKAFSSFCSALR--ET
X_tropicalis_ENSXETP00000035938           ------------------------------------------------------------------------------------------------------------------------
P_pygmaeus_ENSPPYP00000017020             --------------------------------------------------------------------------------------------MENTENSVDSKS----------------
P_troglodytes_ENSPTRP00000054330          --------------------------------------------------------------------------------------------MENTENSVDSKS----------------
H_sapiens_ENSP00000311032                 --------------------------------------------------------------------------------------------MENTENSVDSKS----------------
O_anatinus_ENSOANP00000015596             -------------------------------------------------------------------------------------AGTRRDQARQLVTDLETRGRRALSVFISCLR--ET
O_anatinus_ENSOANP00000000517             --------------------------------------------------------------------------------------------AASGEVMVDSKS----------------
E_caballus_ENSECAP00000019797             --------------------------------------------------------------------------------------------MENSKISVDSKS----------------
D_rerio_ENSDARP00000075318                ----------------------MADQLLENLRPDLIKGLSERVINGLLDDLQQKK-VFGEEEI----------------EDIQHRMKTRADQARHVIDDVKRKGVKASEIMLASLK--TR
M_mulatta_ENSMMUP00000015808              --------------------------------------------------------------------------------------------MENTENSVDSKS----------------
M_domestica_ENSMODP00000004412            -------------------MEESQRELFQKNRLRLVCELQVEP---LWDLMLDRE-LFTRDMIE---------------DIQR--AGTRRDQARQLVTDLQTRGKRALPIFISCLE--AT
B_taurus_ENSBTAP00000003205               -------------------MNEADRLLLRRYRVRLVGELQVAS---LWDALLSRE-LFTPDMIE---------------DIQRAGSGSRRDQARQLILDLETRGSQALPLFISCLE--DT
M_domestica_ENSMODP00000005560            --------------------------------------------------------------------------------------------MEDTGTTVDAKS----------------
R_norvegicus_ENSRNOP00000014096           --------------------------------------------------------------------------------------------MDNNETSVDSKS----------------
D_rerio_ENSDARP00000083664                -------------MLGECGMTKWERLALRRNSVKMLQDLVVDD---LLIQCLQQDGILTDSMAE-----------------SIMAKPTSQGRSHQLLFLLPKRGPRAFSTFCSALK--ET
T_rubripes_ENSTRUP00000040691             -------------------------------------------------------------------------------------TNMSANGPSPGGDFTDAKKGA--------------
C_intestinalis_ENSCINP00000002956         ------------------AMKKRHRNTLIKNRVKLAKCLHLDE---VLQYLVQCG-ILTDVTVE-----------------RITSKPTRFSQNVAFLTCLPTRGPRAYGTFLEALR--IS
O_latipes_ENSORLP00000010095              -----------------------------------------------------------------------------------------MASNRPGEDSTDARK----------------
A_aegypti_AAEL003444-PA                   ---------------------------------------------------------------------------------------------MDTTDELDVLG----------------
C_familiaris_ENSCAFP00000032189           ----------------------------------------------------------------MGEQRNTSSKELAAAEATGQSGKELEVSMENTENSVDAKS----------------
T_nigroviridis_ENSTNIP00000009934         ---------------------------------------------------------------------------------------MSANGPASGEDFTDASKG---------------
T_guttata_ENSTGUP00000017449              -------------------MEERQRRALRRGRARLVAALRVEP---LWEPLEQRG-LFTRPMLE---------------ELQS--AGSRGEQARQLIIDLETRGKQAFPAFLSILR--DT
A_carolinensis_ENSACAP00000009923         ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024812            ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000005556            --------------------------------------------------------------------------------------------MEDTGTTVDAKS----------------
G_aculeatus_ENSGACP00000024816            ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024809            ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000008661            ------------------------------------------------------------------------QVNGA-RLTSAQDVA--AEEGGPTGDQTDAKPDRRGRFLLFGNI----
G_gallus_ENSGALP00000002083               -------------------MEEAQRSALRRGRVRLVEGLRPEV---LWGPLQARG-VFTSAMVE---------------DMQS--TGTRREQARQLVIDLETRGKQAFPIFLSILR--DT
T_guttata_ENSTGUP00000006879              -------------------------------------------------------------------------------------MTDIGDGAHLGKDLADTKS----------------
D_rerio_ENSDARP00000019984                ------------------------------------MDKEALTSENEVSGDDQENYGKGDVTDAKPDPKAMCRVDKE-ALTSEIEVLEEDQDSYGEEDVTDAKPDRKGRFRLFGN-----
T_nigroviridis_ENSTNIP00000022078         ---------------------------------------------------------------------------MAGEAAGIPELGGEAEGEHRCEDDVDAKPDRRGRFLLFKS-----
A_gambiae_AGAP000830-PA                   ----------------------------------------------------------------MSMPDVVDIRNEINKEHVRESLDRNGDEQQLVQDVNDALG----------------
E_caballus_ENSECAP00000015102             -------------------MNEADRQLLRRSRLRLVRELQVDS---LWDALLTRE-LFTPDMIE---------------DIQR--SGSRRDQARQLIIDLETRGSQALLLFISCLE--DT
T_guttata_ENSTGUP00000011206              ------------------------------------------------------------------------------------------------------------------------
G_gallus_ENSGALP00000017288               ------------------------------------------------------------------------------------MMTDIKDGPRSGEDVSDARS----------------
D_rerio_ENSDARP00000006831                ----------------------------------------------------------------------------------------------MNGDCVDAKRVDTT------------
M_domestica_ENSMODP00000036247            TLSVSFTSRTKQLLSVMVILLFNLSEGVGPSELKSIKFMLSSK---IPKCKIEDD-MTLMDLFI---------------EMEKRGILGEGNLDALKIVCDQIDKSLLKKIQEYEIS----
T_rubripes_ENSTRUP00000031759             ------------------------------------------------------------------------SMQMAGEPTEISDLGGEVEEGGQSEDDVDAKPDRKGRFLLFKS-----
D_melanogaster_FBpp0084848                -------------------------------------------------------------------MDATNNGESADQVGIRVGNPEQPNDHTDALGSVGSGGAGSSGLVAGSSH----
G_aculeatus_ENSGACP00000022402            -----------------------------------------------------------------------------------------MSVNGPGEDRTDAKT----------------
A_gambiae_AGAP011951-PA                   ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000023986           -------------------MDEAERRALRRCRVRLVRELQVAA---LWDALLSRE-LFTAAMVE---------------DLQHAGSGSRSDQARQLVIDLETRGSQALPLFISCLE--DT
P_troglodytes_ENSPTRP00000056642          AAEARKRTEAAWSLSWLLAMDEADRRLLRRCRLRLVEELQVDQ---LWDALLSRE-LFRPHMIE---------------DIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLE--DT
B_taurus_ENSBTAP00000021099               --------------------------------------------------------------------------------------------MENTENSVDSKS----------------
M_musculus_ENSMUSP00000030747             -------------------MDEADRQLLRRCRVRLVSELQVAE---LWDALLSRE-LFTRDMIE---------------DIQQAGSGSRRDQARQLVTDLETRGRQALPLFISCLE--DT
D_rerio_ENSDARP00000063081                ------------------MSKKESTQRILQHKVFLIDTLSVEA-SFILQNVQQAK-LITQRDYN-----------------NLSDVSERETKIIKLLDKLIGRGEETCQEFIDLLR----
X_tropicalis_ENSXETP00000003217           -------------------------------------------------------------------------------------MEESHNGVQYGEDTADAKT----------------
O_latipes_ENSORLP00000010793              ------------------------------------------------------------------------------------MDMAETAEELSGKDQVDTKP----------------
P_pygmaeus_ENSPPYP00000002138             -------------------MDEADRRLLWRCRLRLVEELQVDQ---LWDALLSRE-LFRPHMIE---------------DIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLE--DT
R_norvegicus_ENSRNOP00000017972           -------------------MEEADRQLLRRCRVRLVRELQVAE---LWDALLSRE-LFTRDMIE---------------DIQRAGSGSRRDQARQLVIDLETRGRQALPRFISCLE--DT
E_caballus_ENSECAP00000010379             ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000072390                ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000365051                 AAEARKRTEAAWSLSWLLAMDEADRRLLRRCRLRLVEELQVDQ---LWDALLSRE-LFRPHMIE---------------DIQRAGSGSRRDQARQLIIDLETRGSQALPLFISCLE--DT
D_rerio_ENSDARP00000047019                -------------------MEQKHRQILQRHRLNLVKALNPED---VCDKLLSKG-VFTQDMID---------------EIQS--KATRRDQARQLVKDLETRGSLAFPAFLDSLR--ET
A_carolinensis_ENSACAP00000002670         ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000013731             ------------------------------------------------------------------------------MADDQDCVVEQGAGDSTSTDAVDAKPDRSSFVPSLFS-----
G_gallus_ENSGALP00000014503               ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP009832-PA                   ---------------------------------------------------------------------------------QPLTKAFSAMFSRKQEDSSDTRGMPHGS-----------
M_mulatta_ENSMMUP00000040583              -------------------MDEADRRLLRRCRLRLVEELQVDQ---LWDALLSRE-LFKPHMIE---------------DIQRAGSGSRRDQARQLITDLETRGSQALPSFISCLV--DT
O_anatinus_ENSOANP00000019254             ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000023821           ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000018104            ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000012869               EGSLGSGRRSGSDGQPAPPKISPTTEELQSRLQETLDLLSSQELRSFRDHLKKVEPPVS--------------------QVKLELEGHSPSGLAKLLAKHYYPAAVAKRVLVQVLE----
B_taurus_ENSBTAP00000008706               ------------------------------------------------------------------------------------------------------------------S-----
D_rerio_ENSDARP00000075645                -----------------------MDKTSNPNNSNQINRASPNE---------------------------------------QEKIKTDEPKRKNTSQEDKENLHKGVQNNNSPKR----
A_gambiae_AGAP004920-PA                   ----------------------------------------------------------------------------VCGRDILHCKTMNTSTLSTAFDEVDNNT----------------
D_melanogaster_FBpp0071971                --------------------------------------------------------------------MTDECVTRNYGVGIRSPNGSENRGSFIMADNTDAKGCTPESLVVGGAT----
G_aculeatus_ENSGACP00000007379            -------------------MEEIHKRILQRNRINLVRDLDPSS---LYDGLLEKG-VFTQDMID---------------EIKS--AGTRRDQARKLVQDLETRGSRAFAMLLLCLE--ET
C_intestinalis_ENSCINP00000024485         RDYEENFQAQQNNFTTYRVVCFMLADELTEGDLKILKRLCAGK---MSKANVRRS-VDVLSWLT---------------CMEEEDLLSEGDLDFIMSILQHLDNQKPYKLFQRVRMNDNT
A_carolinensis_ENSACAP00000013788         ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000045375             -------------------MEERHKKILQRNRTNLVGELDPSS---LYDGLIEKR-VFTHDMID---------------EIKS--SGTRRDQARQLIRDLETRGSRAFPLFLECLQ--ET
D_rerio_ENSDARP00000071815                ----------------------------------------------------------------------------------------MSDVKPKGVDTVDARQ----------------
O_cuniculus_ENSOCUP00000002346            ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000028116               ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000221740                 ------------------------------------------------------------------------------------------------------------------------
T_rubripes_ENSTRUP00000044662             LPRTGAQDLISPYSCKSRKLLYSLSEELTADDLKDIKFLLNNK---LPRGKLEE--VTTLEVFM---------------ELEHRALISDTDLGFLESIIQPVCPVLLEKINQFNAQ--NC
O_latipes_ENSORLP00000003208              -------------------MEEKHKRILRRNRVHLVKELDLSD---LCDVLLRKD-VFTQSMIN---------------DIKRQNCETKRDQARKLVKDLETRGNEAFSAFLEGLR--VT
D_rerio_ENSDARP00000075650                ------------------MDKKESVDKICENKIFLLETLSVDA-NFILQHVQQAK-LITLRDYN-----------------NLSDFPQRETKIINLLDKLMGKGEETCHQFIALLR----
T_guttata_ENSTGUP00000010625              ------------------QLLYGIAEDLTSEDVRSVKFLLQKQ---LPKNKLQEN-ASMLQVFL---------------EMEIKGIIKEDNMTTLKDILQRFRADIKKKIDAYEEK----
A_aegypti_AAEL014348-PA                   --------------------------------------------------------------------------------------MKKIMFGRKEVNS---------------------
M_musculus_ENSMUSP00000026062             ------------------------------------------------------------------------------MTDDQDCAAELEKVDSSSEDGVDAKPDRSSIISSILL-----

                                                  250       260       270       280       290       300       310       320       330       340       350       360
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000347741                 DQISPNKKAHP--------------------------------------------------------------------------------------NMEAGP--PESGESTDALKLCPH
P_troglodytes_ENSPTRP00000041705          DQISPNKKAHP--------------------------------------------------------------------------------------NMEAGP--PESGESTDALKLCPH
P_pygmaeus_ENSPPYP00000004373             DQISPNKKAHP--------------------------------------------------------------------------------------NMEAGP--PESGESTDALKLCPH
M_mulatta_ENSMMUP00000012893              DQISPSKKAHL--------------------------------------------------------------------------------------NMEARP--PESGESADALKLCPH
B_taurus_ENSBTAP00000027820               DKNSTSIKAPE--------------------------------------------------------------------------------------ETVAGP--DESVGSAATLKLCPH
P_troglodytes_ENSPTRP00000007279          DQKITSVKPLL--------------------------------------------------------------------------------------QIEAGP--PESAESTNILKLCPR
H_sapiens_ENSP00000376849                 DQKITSVKPLL--------------------------------------------------------------------------------------QIEAGP--PESAESTNILKLCPR
P_pygmaeus_ENSPPYP00000004374             DQKITSVKPLL--------------------------------------------------------------------------------------QIEAGP--PESAESTNTLKLCPR
G_gorilla_ENSGGOP00000015374              DQKITSVKPLL--------------------------------------------------------------------------------------QIEAGP--PESAESTNILKLCPR
E_caballus_ENSECAP00000010831             DRSVISRKALE--------------------------------------------------------------------------------------EIAAGP--AESAEPTDTLKLCPH
M_mulatta_ENSMMUP00000012894              DQRITSVKSLL--------------------------------------------------------------------------------------QIEAGP--PESAESTNTLILCPH
C_familiaris_ENSCAFP00000031565           DKYSTSVEAFV--------------------------------------------------------------------------------------ENMPGPTIPDSEESTDTLKLCPP
M_musculus_ENSMUSP00000027012             DPGSHHG------------------------------------------------------------------------------------------EANLEM--EEPEESLNTLKLCSP
R_norvegicus_ENSRNOP00000058685           DSGSHHG------------------------------------------------------------------------------------------EANLEM--EEPEESVDTLKLCSS
M_musculus_ENSMUSP00000027009             QEQLS-LQFSND----------------------------------------EDDGPQ-KI-----CTPSSPSESKRKVEDDEMEVNAGLAHESHLMLTAPHG--LQSSEVQDTLKLCPR
R_norvegicus_ENSRNOP00000029448           DKQLSLLQADRN----------------------------------------QITGPSFQI-----LVFNSLSESRGKVEDEEMEVNVGVAHASHLMLTVPQG--IQSTEVQDSLKLCSR
P_troglodytes_ENSPTRP00000059619          DNYLAGTLGLSA-----------------------------------------------------------DQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAM--PTSSGSEGNVKLCSL
H_sapiens_ENSP00000260309                 DSYLAGTLGLSA-----------------------------------------------------------DQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAM--PTSSGSEGNVKLCSL
E_caballus_ENSECAP00000006810             KKQMNLKSLADY----------------------------------------EDDESE-DT-----ESPFSSTESACEGEDEETEENAGLSQASVPPMTDPQE--TQVSQPKDKLKPCSH
P_pygmaeus_ENSPPYP00000004377             DSYLAETLGLSA-----------------------------------------------------------DQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAM--PTSSGSKGNVKLCSL
E_caballus_ENSECAP00000021890             DPHLAETLRLSS-----------------------------------------------------------GPQSGNFLKTQDSQAVVHSSPALQAMPDDLAK--LALSGPKVSLKLCSP
M_domestica_ENSMODP00000034022            DGHLAEKLGLSS-----------------------------------------------------------ELNSNQSHISLCREQAPRPINICILRNDNIER-TTMNPGYLDTLKLCSY
M_domestica_ENSMODP00000034033            DGHLAEKLGLSS--------------------------------------------------------------GKRKYLLGKADHSIHGEKLKTKQRHTIGKWKVIHDDAIDTLKLCSY
O_anatinus_ENSOANP00000016591             NPFVAAKLGLSA------------------------------------------------------GGQGQSGNTQFVGQSQMIPAVATSCSVPQALQAPKTLTESHPDGSGEILKLCPS
B_taurus_ENSBTAP00000027821               DSHLAGILGLTS-----------------------------------------------------------GSQSENYLR-QKPQAVVPPFPAPQAMLDNPVK--LASSGPGGNLKLCPP
M_domestica_ENSMODP00000034020            ---------------------------------------------------------------------------------------------------LIAS--TAQTGSSGKLKVCSR
O_cuniculus_ENSOCUP00000000956            DCHLAGLLGLSS-----------------------------------------------------------GPQSENHFNAQDSLEAFSSFSAPQTTQDNQVV--FTFSGP--SLKLCPL
M_mulatta_ENSMMUP00000021744              -------------------------------------------------------------------------------------------------LSAPLE--IQGAQPSGRLKLCPH
C_familiaris_ENSCAFP00000021904           GSLLSLSWSSTS----------------------------------------ATKPSGSCR-----PSYLTQARSRKKEEVPKILVFVIFLYKMVF-LLQVLQ--EIQASQVKVRKLCPC
P_pygmaeus_ENSPPYP00000004372             KKQL--------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000027015             DCYLAGILELQS-----------------------------------------------------------APSAETFVATEDSKG-GHPSSSETKEEQNKED--GTFPGLTGTLKFCPL
P_troglodytes_ENSPTRP00000047678          KKQL--------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000009993           DCYLAEILELQS-----------------------------------------------------------GPSAETVFVTEDSKG-GHPFSSETKEKLNKEG--GAFPGPSGSLKFCPL
H_sapiens_ENSP00000364878                 KKQL--------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000012901              --------------------------------------------------------------------------------------------ASLAMQDNPAM--PTSSGSKGNVKLCSQ
O_cuniculus_ENSOCUP00000006490            DQNSTGMQXXX--------------------------------------------------------------------------------------XXXXXX--XXXXXXXXXXXXXXX
G_gallus_ENSGALP00000001569               DCNLAEQLRLCA-----------------------------------------------------------------------HAEPPGAPLAAPSTVGFSDP--PVSSQDLQWIQQCPL
X_tropicalis_ENSXETP00000017024           HKTLAKNMGLDV---------------------------------------------------------------------------SEPAIAPQPIQEQNKK--TNENTEISSVIHCSD
G_aculeatus_ENSGACP00000013201            DSSLFSELGLSS--------------------------------------------------------------------------------------AQTAP--PAISGVSNIFKLVSP
A_carolinensis_ENSACAP00000013361         ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000034228                KCNAVAEELLEN------------------------------------------TGQVYSIFKLCKKNSHYTKPPIIITDVFMFCFLGGVSQPEPPVPEPIPK--DPAQLKELKVTPCSQ
T_rubripes_ENSTRUP00000019853             DPELSAVLGLSC---------------------------------------------------GHPAPP--------GELRDDTLFQTDRIVSFRFQP-------QSPRWKVKGHLQLPH
T_rubripes_ENSTRUP00000035020             DPELSAVLGLSC---------------------------------------------------GHPAPPVFNRRAPDGRSR-------VIFNSPINRCVLEGE--TERQRRERALKISPG
O_latipes_ENSORLP00000007938              DPILFSELGLSC------------------------------------------------------------------------------------PEPAQTN--SHSQRDEPATTVLTA
T_rubripes_ENSTRUP00000013027             DPELSAVLGLSC---------------------------------------------------GHPAPP--------GELR-------GQLESPAF-----ST--AEPQMEGQGSSSTPP
D_rerio_ENSDARP00000059407                KQNERANRLESK------------------------------------LLEAVSSSDLFQPQAQENEQNPEDP----------------QSINTSG----------------------FQ
D_rerio_ENSDARP00000068268                KQNERAKRLESN------------------------------------LLKV-------QSQGQENKQNSEEPQPIPQIISQPIQQIISQPINNAGSEDLQPI--QADWQRPRQIIPCSQ
D_rerio_ENSDARP00000008601                KQREFLEENLAA------------------------IVARRLFDFKSCPGCQSHVERRNRNNLCVKCTICTANMTQTYYFCWKCRREWKGVTNNAECCGNTGC--GQSVTEPDPLKPCTP
X_tropicalis_ENSXETP00000015203           GQRHLAEQLEEE--------------------------------AQQQQMESVTPEVHERSFPLPVQEST-----------------PSRPRRQFCR-EYNEE--SIDDGDGPGTVQL--
G_gallus_ENSGALP00000029853               KQQHLAEMILKT---------------ESS--LR--------------HGIATLEQRYGSNLPLPLSESCNSK--------------RPRLIVFFCT-KPVEH--SLDSGDGPPIPPVKH
G_gorilla_ENSGGOP00000011776              KKQL--------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000006831         KQPHLEEMLLLN---------------LIDFLLF----------------HHVIVPPQNAHLPL--HTVCDLL--------------PFAYQLFISSAEPMEH--SLDDGDGPHYPQVMP
M_musculus_ENSMUSP00000031895             RQGHLEDLLLTT---------------LSD--IQ--------------HVLPPLSCDYDTSLPFSVCESC-----------------PPHKQLRLST-DATEH--SLDNGDGPPCLLVKP
R_norvegicus_ENSRNOP00000022672           RQGHLEDLLLTT---------------LSD--IQ--------------HILPPLSCDYDSSLPFSVCESC-----------------PPHKQSRLST-DTMEH--SLDNGDGPPCLQVKP
E_caballus_ENSECAP00000003321             KQGHLEDLLLTT---------------LSG--LQ--------------HVLPPLSCDYDLSLPFPVCESC-----------------PPHKQLRLST-DTVEH--SLDNGDGPPCLQVKP
P_pygmaeus_ENSPPYP00000020323             KQGHLEDMLLTT---------------LSG--LQ--------------HVLPPLSCDYDLSLPFPVCESC-----------------PLYKKLRLST-DTVEH--SLDNKDGPVCLQVKP
O_anatinus_ENSOANP00000005545             KQGHLQDLLYRT---------------LSN--LSPPSTAVGALGTQGEELAGRLGGRWRGLPSLPSVSVCPVVVCPFLMVLGNSRLQPALSVGDLLP-EEMEH--SLDNGDGPPCPQVKP
T_guttata_ENSTGUP00000013612              QQQHLETLILKT---------------MSS--LS--------------QEIARLEHCHESDLPYPASESCNSK--------------RPRWL------EPMEH--SLDNRDGPSIPPVKY
H_sapiens_ENSP00000312664                 KQGHLEDMLLTT---------------LSG--LQ--------------HVLPPLSCDYDLSLPFPVCESC-----------------PLYKKLRLST-DTVEH--SLDNKDGPVCLQVKP
P_troglodytes_ENSPTRP00000033921          KQGHLEDMLLTT---------------LSG--LQ--------------HVLPPLSCDYDLSLPFPVCESC-----------------PLYKKLRLST-DTVEH--SLDNKDGPVCLQVKP
M_mulatta_ENSMMUP00000016588              KQGHLEDIELKL---------------RVS--AL--------------MKPTGLGSDYNDILGLMVKLNT------------------VFWFSVYTT-DTVEH--SLDNKDGPVCLQVKP
B_taurus_ENSBTAP00000024166               KQSHLEELLLRT---------------LSG--LQ--------------PVVPPLSCDYDLSLPFPVCESC-----------------TRHKRLHLSP-DAVEH--SLDHGDGPPCLQVKP
C_familiaris_ENSCAFP00000005409           KQGHLEDLLLTT---------------LSG--LQ--------------HGLPPLSCDYDLSLTFPMCESC-----------------PPQKQLRLSP-DTVEH--SLDNGDGPPCLQVKP
O_latipes_ENSORLP00000015114              EQEHLCDLLTQE-------------------------EEGREVCLDTPLINSEEQSEVSSSMSYPIHDSE------------------GLQLEMRTNTESMES--SLD-ADSPINTPVLA
M_domestica_ENSMODP00000001598            KQGHLEDLLHRT---------------LYS--FQ--------------NLRPPLGCDYDSSFPLPVCDSC-----------------PPHKQLRLSV-ETMEH--SLDNGDGPPSLQVKP
G_aculeatus_ENSGACP00000013740            EQQHLYELLIQS-----------------------SEKDGKE----TPGMLMCGQF-IDSSLPLPTQEVV------------------AAK-RARTQAESMEF--SLD-ADSPINSPVLP
C_elegans_C48D1.2                         GHEGLAEVLEPL---ARSVDSNAVEFECPMSPASHRRSRALSPAGYTSPTRVHRDSVSSVSSFTSYQDIYSRARSRSRSRALHSSDRHNYSSPPVNAFPSQPS--SANSSFTGCSSLGYS
M_musculus_ENSMUSP00000091238             ------------------------------------------------------------------------------------------------------I--NNFE---VKTIHGSK
T_nigroviridis_ENSTNIP00000010874         DQKHLCDLLART-----------------------SQENGNG---------THLETCVDSSVPLPTQEAV--------------------PAKRARTQESMEI--SLD-ADSPINTPVCP
X_tropicalis_ENSXETP00000035938           -----------------------------------------------------------------------------------------------------ST--KKKKTEDPEKPPQAS
P_pygmaeus_ENSPPYP00000017020             ------------------------------------------------------------------------------------------------------I--KNLE---PKVIHGSK
P_troglodytes_ENSPTRP00000054330          ------------------------------------------------------------------------------------------------------I--KNLE---PKIIHGSQ
H_sapiens_ENSP00000311032                 ------------------------------------------------------------------------------------------------------I--KNLE---PKIIHGSE
O_anatinus_ENSOANP00000015596             DQHALAALLSEG-----CQAPQVTPV--DIRPVEIIRPGGQGDVCKYSKIHPK----CYSPPLPFQ-----------STSPLRGKEQWTGSVKPFV---------PVPSTTKREQEATR-
O_anatinus_ENSOANP00000000517             ------------------------------------------------------------------------------------------------------F--HSSQGYSSRKVPGKQ
E_caballus_ENSECAP00000019797             ------------------------------------------------------------------------------------------------------I--KNSE---TKILHGSK
D_rerio_ENSDARP00000075318                DPHLYDTLGIER----------------------------------------------------------------------------------------LLV--PVPETELTPSQLSET
M_mulatta_ENSMMUP00000015808              ------------------------------------------------------------------------------------------------------I--KSLE---PKIIHGSK
M_domestica_ENSMODP00000004412            GQWDLAALLSES-----NTTLTQQPDPIDIKPVEMIRSGGLRSTGRYT----------SMVSLHLLLLANSPFLYFIDAVLVSAHNLFPLELIKRQ--PTFSK--VLSLLYKLRFPFCPP
B_taurus_ENSBTAP00000003205               GQDTLASLLKTS-----RQAAKQ-----------------------------------SKPSQGKL-----------APVVLGPEELWPAKLRPEVLRPEVPR--AVDAGSGGFTDVCP-
M_domestica_ENSMODP00000005560            ------------------------------------------------------------------------------------------------------I--KNSG---VKSLHSSK
R_norvegicus_ENSRNOP00000014096           ------------------------------------------------------------------------------------------------------I--NNFE---TKTIHGSK
D_rerio_ENSDARP00000083664                EQHHLCKLLMDF-----------------------------------------TEKDKKNSQYKLSPEIC------------------KKKNKHTHTHKSMEM--CLD-ADSPVTTAVLP
T_rubripes_ENSTRUP00000040691             ------------------------------------------------------------------------------------------------------G--QQPRSGSSS---GRV
C_intestinalis_ENSCINP00000002956         SQEHLVDILEKV-----------------------------------------------DISNAIPNNKPITPTTLHATITSNVHSEFVCARRQPMEIGKCED--KNDAKDGHNRLRVQN
O_latipes_ENSORLP00000010095              ------------------------------------------------------------------------------------------------------D--NGELAAGASPAPDRM
A_aegypti_AAEL003444-PA                   --------------------------------------------------------------------------------------------------------------FGSRTNESSK
C_familiaris_ENSCAFP00000032189           ------------------------------------------------------------------------------------------------------F--KNAE---TVIV---K
T_nigroviridis_ENSTNIP00000009934         ------------------------------------------------------------------------------------------------------G--EQPSGSSSS---GKM
T_guttata_ENSTGUP00000017449              GQGHLAEMLMQE-----CESRPVPPQLPDLRPVELEL----------------------------------------------------QEANQRCAVVLQTA--ARDVAAGIPLTVGK-
A_carolinensis_ENSACAP00000009923         ----------------------------