10        20        30        40        50        60        70        80        90       100       110       120
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000376897                 ----------------------------MNIVEN-SIFLSNLMKSAN-TFEL-KYDLSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKK
P_troglodytes_ENSPTRP00000007250          ----------------------------MNIVEN-SIFLSNLMKSAN-TFEL-KYDLSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPIEKHKK
M_mulatta_ENSMMUP00000004533              ----------------------------MNIVEN-SIFLSNLMKSAN-TFEL-KYDLSCELYRMSTYSAFPAGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPVEKHKK
P_pygmaeus_ENSPPYP00000004355             ----------------------------MNIVEN-SIFLSNLMKSAN-TFEL-KYDLSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPIEKHKK
E_caballus_ENSECAP00000010270             ----------------------------MNIVEN-SVFLSNLMKSAN-MFEL-KYDFSCELYRISTYSTFPPGVPVS-ERSLARAGFYYTGINDRVKCFCCGLMLDNWKQGDNPTEKHKK
B_taurus_ENSBTAP00000034604               ----------------------------MNIVEN-SVFLSNLMKSAN-MFEL-KYDFSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGVKDKVKCFCCGLMLDNWKQGDNPIEKHKK
R_norvegicus_ENSRNOP00000007702           ----------------------------MNMVQG-SAFLAKLMKSAD-TFEL-KYDFSCELYRLSTYSTFPAGVPVS-ERSLARAGFYYTGVNDKVKCFSCGLMLDNWKQGDSPIEKHRK
M_musculus_ENSMUSP00000013949             ----------------------------MNMVQD-SAFLAKLMKSAD-TFEL-KYDFSCELYRLSTYSAFPRGVPVS-ERSLARAGFYYTGANDKVKCFCCGLMLDNWKQGDSPMEKHRK
M_domestica_ENSMODP00000000728            -----THKTTSQRKT---CPLLFPKYSIMSVVED-GVLLSHLMSSDT--HEM-KYDLSCELYRMSTYSAFPVNVPIS-ERSLARAGFYYTGVNDRVKCFCCGLMLDNWKQGDNAIDKHKQ
C_familiaris_ENSCAFP00000022282           ----------------------------MNIVQN-SIFLSNLLRSSP-VFEL-KYDHSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGAKDRVRCFCCGLMLDNWKAGDSPTGKHRN
E_caballus_ENSECAP00000000598             -------------------------------MED-STILSSWTVGNK--QKM-KYDFSCELYRMSTYSTFPTGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDNPIEKHKQ
C_familiaris_ENSCAFP00000022277           ----------MHKTTSQRLVPG-SYQRIKRTMED-STILRNQTIGNK--QKI-KYDFSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKPGDNPVEKHKQ
O_anatinus_ENSOANP00000016616             -----VHKTTSRGETRPVSPATPTEYFVMNVVAN-SMFLSNLMNGNS-GYEL-KYDFSCELFRMSTYSTFPTNVPVS-ERSLARAGFYYTGASDKVKCFSCGLMLDNWKPGDSAIEKHKQ
T_guttata_ENSTGUP00000013125              ----------------------------LNTVED-SPFLTSIMRQSALCDEL-KYDLSCELYRMSTFSTFPMNTPVS-ERSLARAGFYYTGVQDKVKCFSCGLTLDNWQPGDNAMEKHKQ
P_pygmaeus_ENSPPYP00000004357             ----------MHKTASQRLFPGPSYQN-KSIMED-STILSDWTNSNK--QKM-KYDFSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQ
M_mulatta_ENSMMUP00000004536              ----------MHKTASQRLFPGPSYQNIKSIMED-STILSDWTNSNK--QKM-KYDFSCELYRMSTYSTFPTGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIEKHKQ
H_sapiens_ENSP00000227758                 ----------MHKTASQRLFPGPSYQNIKSIMED-STILSDWTNSNK--QKM-KYDFSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQ
P_troglodytes_ENSPTRP00000007251          ----------MHKTASQRLFPGPSYQNIKSIMED-STILSDWTNSNK--QKM-KYDFSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQ
G_gallus_ENSGALP00000035646               ----------------------------MNIMDS-SPLLASVMKQNAHCGEL-KYDLSCELYRMSTFSTFPVNVPVS-ERRLARAGFYYTGVQDKVKCFSCGLVLDNWQPGDNAMEKHKQ
R_norvegicus_ENSRNOP00000014560           ------------------------------IMEN-STVLSNWTKENK--EKM-KYDFSCELYRMSTYSAFPRGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPTEKHRQ
M_musculus_ENSMUSP00000091422             ----------MDKTVSQRLGQGTLHQKLKRIMEK-STILSNWTKESE--EKM-KFDFSCELYRMSTYSAFPRGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDSPVEKHRQ
A_carolinensis_ENSACAP00000012475         ----------------------------LIIMNTFDTFAAKLKNVPD-VGQL-KYDLSCELFRMSTFSTFPLHVPVS-ERSLARAGFYYTGVKDKVKCYSCGLMLDNWKKGDNPLDKHKQ
O_cuniculus_ENSOCUP00000011948            -----------HKTTSPRVVPG-TVYRTQNMMED-STILXXXXXXXX--XXX-XXXXXXXXXXXXXXXXSPNGVPVS-ERSLARAGFYYTRVNDKVKCFCCGLMLDNWKQGDNPIEKHKQ
M_domestica_ENSMODP00000000705            ----------------------------MNLVEN-IMFLSNMNISNL--YEL-KYDFSCELYRISTYSAFPVNVPVS-ERSLARAGFYYTGVNDRVKCFCCGLMLDNWKQGDNAIDKHKQ
O_cuniculus_ENSOCUP00000008710            ----------------------------MNIVEN-SIFLANLMKSAN-TFEL-KYDFSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKQGDKPIEKHRK
X_tropicalis_ENSXETP00000048002           --------------------------MANEILDR-RPDLAKRLKSNPSMCKI-TLEFSCELYRLSTFSTFPSNTHVS-ERNLAKAGFYYTGQDDKVKCFTCGLMLDNWKKGDNAFEKHKK
T_nigroviridis_ENSTNIP00000012883         --L----PALFEGLLPFILLCFDTKMETLVQLKN-NPFLMGLCRNCP-PPDL-QYDNSSELYRISTFARFPS-SGVT-ERSLARAGWFYTGVGDRVQCFKCNVTAEGWQAGDCPTEKHRQ
T_rubripes_ENSTRUP00000043752             --LLSPDPPLGGPTFTLILLCFHTKMETLVQLKN-NPFLMGLCRNCP-PPDL-QYDNSSELYRISTFARFPT-SGVT-ERSLARAGWFYTGVGDRVQCFKCNVTAEGWQAGDCPTEKHRQ
G_aculeatus_ENSGACP00000027283            --------------------------------KN-NPFLMGLCRNGP-PPDL-QYDNSSELFRISTFARFPA-SGVT-ERSLARAGWFYIGVGDRVQCFRCNVTAEGWQAGDCPTEKHRQ
D_rerio_ENSDARP00000065554                IYMRTHTQGMTIKPFSLLAIPFPISLSQMEILQN-SAFLRGLCRTSG-PADL-QYDNSSELFRISTYAKFPTTAAVT-ERSLARAGFYYTGLGDRVQCFRCNVTADNWQSGDCPAERHKQ
O_latipes_ENSORLP00000006992              ----------------------------LVQLKN-SKFLMGLCRNGP-PSDL-QYDNSSELFRFSTFARFPT-SVVT-ERSLARAGWFYTGVGDRVQCFRCNVTAEGWLAGDCPTEKHRQ
G_gorilla_ENSGGOP00000005705              ----------------------------MNIVEN-SIFLSNLMKSAN-TFEL-KYDLSCELYRMSTYSTFPAGVPVS-ERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPIEKHKK
O_cuniculus_ENSOCUP00000014265            -----MHKTASQRVV------PGTSYRIKSMMED-STISSNTNDQNQ---KM-KYDFSYKI-RVPTYSGLPIRVPLS-EWSLAPAGLYYIGMN-KVKCFCCDLMLDNWKQEYNLIEKHKQ
G_gorilla_ENSGGOP00000008137              ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000046955               ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075338                ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000360242                 --------------------------MTFNSFEGSKTCVPADINK--------EEEFVEEFNRLKTFANFPSGSPVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK
C_familiaris_ENSCAFP00000034255           --------------------------MTFNSFEGAKTCVPAGINK--------DEEFVEEFNRLKTFANFPSSSPVS-ASTLARAGFLYTGEGDTVRCFSCHASIDRWQYGDSAVGRHRK
P_pygmaeus_ENSPPYP00000023167             --------------------------MTFNSFEGSKTCVPADINK--------EEEFVEEFNRLKTFANFPSGSPVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK
M_musculus_ENSMUSP00000110746             --------------------------MTFNSFEGTRTFVLADTNK--------DEEFVEEFNRLKTFANFPSSSPVS-ASTLARAGFLYTGEGDTVQCFSCHAAIDRWQYGDSAVGRHRR
P_troglodytes_ENSPTRP00000038304          --------------------------MTFNSFEGSKTCVPADINK--------EEEFVEEFNRLKTFANFPSGSPVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK
O_cuniculus_ENSOCUP00000008505            --------------------------MTFNSFEGSKTCVPADINK--------DEEFVEEFNRLKTFANFPSSSPVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK
E_caballus_ENSECAP00000017630             --------------------------MTFNSFEGSKTCVPADIDK--------DEEFVEEFNRLKTFANFPSSSPVS-ASTLARAGFLYTGEGDTVQCFSCHAAVDRWQYGDSAVGRHRK
T_guttata_ENSTGUP00000003825              ----------------------------------------ADTDG--------AREWAQERERQGTFVGFPQGCPVS-VLALAQAGFVYTGEGDKVKCFSCNTTIEGWVPGDSALERHKK
B_taurus_ENSBTAP00000053449               --------------------------MTFNSFEGSKTCVPADIDK--------DEEFVEEFNRLKTFANFPSSSPVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAIGRHRR
G_gallus_ENSGALP00000038337               --------------------------MTCNGPDSSESGATPATDG--------DQEWTQEHYRLGTFVEFPHDCPVS-ASALARAGFVYTGEGDKVKCFSCHVTVEGWEPGDSAIDRHKN
R_norvegicus_ENSRNOP00000009358           --------------------------MTFNSFEGSRTVVPADTNK--------DEEFVEEFNRLKTFANFPSSSPVS-ASTLARAGFLYTGEGDTVQCFSCHAAVDRWQYGDSAVGRHRR
C_intestinalis_ENSCINP00000000045         ----------------------------------------------------------MESYRLSTFMKYPQDTPVN-PRHLAAAGFHYTGYKDRVKCFCCGLCVESWCVGDD-VKSPRW
X_tropicalis_ENSXETP00000030727           ----------------------------NEILDR-RPDLAKRLKSNPSMCKI-TLEFSCELYRLSTFSSFPSNTHVS-ERNLAKAGFYYTGQDDKVKCFTCGLMLDNWKKGDNAFEKHKK
T_nigroviridis_ENSTNIP00000006583         ------------------------------------------------------------------------------------------------------------------------
M_domestica_ENSMODP00000018715            --------------------------MTFKSFEDSKTCVPPDINK--------DEDFVEEFNRLKTFANFPSSSPIS-ASTLARAGFLYTGEGDTVKCFSCHAAVDRWQYGDSAVGRHRK
X_tropicalis_ENSXETP00000035327           --------------------------LAEFVLKEEMTCQCPKMSDGAYDMDV-DQNYFEEEVRLASFANFPSSYPVS-APALARAGFYYTGDGDRVKCFSCLAMVEGWQHGDTAIGKHRK
C_intestinalis_ENSCINP00000009820         -------------------------------------------------------DAAMESYRLSTFMKYPQDTPVN-PRHLAAAGFHYTGYKDRVKCFCCGLCVENWVSGDE-IKSKKW
T_rubripes_ENSTRUP00000011958             ------------------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000003419            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000005161         -------------------------------------------------------DSAMESYRLSTFMKYPQDTPVN-PRHLATAGLYFTGYKDRVKCFCCGLATEQWQFGDD-EKSPRW
O_latipes_ENSORLP00000010149              ---------------------------------------------------------------------------VS-PLQLAEAGFLFTGVSDRVRCFSCQKTVENWSQEDQPVDRHIQ
X_tropicalis_ENSXETP00000029187           ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000011315         -----------------------------------------------------------ELSRQQTFASFPSDCPVS-SAALAQAGFFYTGERDQVKCFSCHTMVEGWQEGDSAIERHRT
D_melanogaster_FBpp0086432                ---------------------------------------------------MTELGMELESVRLATFGEWPLNAPVS-AEDLVANGFFATGNWLEAECHFCHVRIDRWEYGDQVAERHRR
G_gorilla_ENSGGOP00000008442              --------------------------MTFNSFEGSKTCVPADINK--------EEEFVEEFNRLKTFANFPSGSPVS-ASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRK
O_anatinus_ENSOANP00000006435             --------------------------MTCNSPEELRTSNPSEVNK--------DEEFAEEHNRLRTFANFPSTSPVS-SSTLARAGFLYTGEEDVVRCFSCHVAVDRWQYGDSAIGRHRK
T_rubripes_ENSTRUP00000010298             -----------------------MNPFDNMQLKKEITMEDQQHDSGTLETDS-AEDFSLITSRLESFRGSNLVQLVP-AERLARAGFHFIGPSDRVRCFSCHKTVENWCTGDRPVERHKE
A_aegypti_AAEL006633-PA                   ------------------------------------------------------------------------------------------------------------------------
O_latipes_ENSORLP00000012199              ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000013586                ---------------------------FPPQRNLVTTNMAHSTHNGELESDNVAADWSVMKNRVNSFQRFPYSEDIS-AQRLARAGFYFTGEGDRVQCFSCSATVQNWNRGDTPLERHQL
G_gallus_ENSGALP00000009239               -------------------------------------------------------------------------------------------------------------MADTAPVEGTH
T_nigroviridis_ENSTNIP00000018867         -------------------------------------MEDQRHDNSNLETDS-AEDFSLIKSRLESFRGSSLVQRVP-AERLARAGFYLVGPSDRVRCFSCQKTVENWSREDRPVERHKE
T_guttata_ENSTGUP00000007779              -------------------------------------------------------------------------------------------------------------MGDAAPAQQPE
C_intestinalis_ENSCINP00000002256         ----------------------------------------------------------MESYRLSTFMKYPQDTPVN-PRHLAAAGFHYTGYKDRVKCFCCGLCVESWCVGDD-VKSPRW
G_aculeatus_ENSGACP00000024474            ---------------------------VPPSSILSSSIMCALRQDNQLESDH-MADFSEINNRLDSFRGSSLAQQVP-AERLARAGFYYTGNADRVCCFSCEKTVENWCRGDTPLERHKE
M_domestica_ENSMODP00000021022            ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000057704           ------------------------------------------------------------------------------QNKLANAGFYYVGPEDRVRCFSCGGQFEMWEEWDFPLTRHQQ
P_troglodytes_ENSPTRP00000019640          ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000024483           MAEHGEASEDQVSEFDGECLPELSALLGVDAVQLVKSQEEEENKERMKMKKGFNAQMRSEAKRLKTFVTYDAFKSWT-PQEMAAAGFYYTGVRHGVQCFCCSLILFGTSLRKVPIESHRK
C_intestinalis_ENSCINP00000000487         ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000321377                 ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000004317               MATQEKAPEERISQFDYALLPEMSAFLGVNALQFVKEIEEKEHRDREKMQKGFNSQMRSEAKRLKTFVTYNTFRSWT-SQEMAEAGFYLTGTKSGIQCFCCSLILFGTSLQNTPMEHHKK
M_musculus_ENSMUSP00000112867             MAEHGESSEDRISEIDYEFLAELSARFGMNLVQLAKSQEEEDHKERMKMKKGFNSQMRSEAKRLKTFESYDTFRSWT-PQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKLPIERHKK
M_musculus_ENSMUSP00000058611             MAEHGESSEDRISEIDYEFLPELSALLGVDAFQVAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFRSWT-PQEMAAAGFYHTGVRLGVQCFCCSLILFGNSLRKLPIERHKK
G_gorilla_ENSGGOP00000008152              ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007294-PA                   ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000113890             MAAQGEAVEEIICEFDDDLVSELSTLLRVDALSVLKRQQEEDHKTRMKMKKGFNSQMRSEAKRLKTFETYDKFRSWT-PQEMAAAGFYHTGVKLGVQCFCCSLILFSTRLRKLPIENHKK
X_tropicalis_ENSXETP00000016312           ------------------------------------------YSGSQNPGEKPLGDMNDEYSRLETYRGHSQYFPMANQRKLAQAGFSYVGPGDRVRCISCGGELEKWERWDVPLTRHQH
H_sapiens_ENSP00000217169                 ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000023641          ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000021651         --------------------------MLVDSFCSNLKYQTMFHNIDRVSQHAAAMDYSSKSNRIQSLENFP-SAPVN-PIQLAIHGFYFTGVEDCVVCFSCENSVRNWKLGDKEGDK-KW
P_troglodytes_ENSPTRP00000048273          MATQQKASDERISQFDHNLLPELSALLGLDAGQLAKELEEKEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYSSWI-PQEMAASGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKR
C_intestinalis_ENSCINP00000020067         ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000012096              ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000194097                 MATQQKASDERISQFDHNLLPELSALLGLDAVQLAKELEEEEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYSSWI-PQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKR
C_intestinalis_ENSCINP00000000466         --------------------MELANNLFSDIETDGMKVNTTSEPSDKRCVYITPGQKEREDYRITTFNKFPSNKPVD-KMKLSSNGFLYTGFKDRVKCFRCGQCVEGLNGTEN-MGLPGW
P_pygmaeus_ENSPPYP00000017359             MATQQKASDERISQFDHDLLPELSALLGLDAVQFVKEIEEEEQKERAKMQKGYNSQMRSEAKRLKTFVTYEPYSSWI-PQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKR
G_gorilla_ENSGGOP00000007398              ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000104503             ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000022142             MAEHGESSEDRISEIDYEFLPELSALLGVDAVQLAKSQEEEEHKERMKMKKGFNSQMRSEAKRLKTFETYDTFRSWT-PQEMAAAGFYHTGVKLGVQCFCCSLILFGNSLRKLPIERHKK
P_pygmaeus_ENSPPYP00000012543             ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000010449         -----------------MQARMMDIRCDGLRVVHNDGRLVPSATNSERELYTRPGDPYYESYRLATFTNYP-NQNIN-VRQVARAGFYFISYQDQVKCFSCGQICEDLQQYDD-MSLPQW
C_intestinalis_ENSCINP00000000510         ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000016315           -----------------------------------------------------------------------KHFPYQTSDKLAWAGFFYVGPGDRVRCFSCGGEVDNWEPGDVPLTRHQL
X_tropicalis_ENSXETP00000034890           -----------------------------------------------------------------------KHFPYMKEWDLAQAGFYYVGPGDRVRCISCNAELEKWEKWDEPLTRHQH
E_caballus_ENSECAP00000017749             ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000018803           ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000009897         -------------------------------------------------------------------------STWA-PLEMAAAGFYHTGTKTAIQCFCCGLVLLARSIKRSPYVEHKK
A_aegypti_AAEL009074-PA                   ------------------------------------------------------------------------------------------------------------------------
E_caballus_ENSECAP00000002314             MATEEKAPAGRDSRFDHALLQELSALLGIDAVQYAKEMEEEEQREREKMQQGFNSRMRSEAKRLKTFATYEAYSSWT-PQEMAAAGFHFTGVRAGVQCFCCGLILFGASLHKRPLDDHKR
D_melanogaster_FBpp0075254                --------------------------------------------------------------MASVVADLPSYGPIA-------------------------------------------
A_carolinensis_ENSACAP00000005440         ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000011648         ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007292-PA                   ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007293-PA                   ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007291-PA                   ------------------------------------------------------------------------------------------------------------------------
O_cuniculus_ENSOCUP00000002871            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002312         ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000040836              ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000013345         --------------------MPLGRFGSKKQSKNAKCRFEHLMVMAKENPDRIFDLSDCELHEVPNLMFSQCRVLLTESLLLHSNLLKSLKHGGKMSCLTSLRVLDLHNNRIALLPKDIG

                                                  130       140       150       160       170       180       190       200       210       220       230       240
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000376897                 LYPSCRFVQSLNSV--NNLEATSQPTFPSSVTNS---------------THS-LLPGTENSGYFRGSY-SN-SPSNPVNSRANQDFSALM-RSSYHCAMNNENARLLTFQT-WPLT---F
P_troglodytes_ENSPTRP00000007250          LYPSCRFVQSLNSV--NNLEATSQPTFPSSVTNS---------------THS-LLPGTENSGYFGGSY-SN-SPSNPVNSRANQDFSALM-RSSYHCAMNNENARLLTFQT-WPLT---F
M_mulatta_ENSMMUP00000004533              LYPSCRFVQSLNSV--NNSEATSQPAFPSSVTNS---------------THS-LLPGTENSGYFSGSY-SS-FPSNPVNSRANQDFSALM-RSSYHCAMNNEKARLLTFQT-WPLT---F
P_pygmaeus_ENSPPYP00000004355             LYPSCRFVQSLNSV--NNLEATSQPTFPSSVTNS---------------THS-LLPGTENSGYFSGSY-SS-FPSNPVNSRVNQDFSALM-RSSYHCAMNNENARLLTFQT-WPLT---F
E_caballus_ENSECAP00000010270             LYPSCSFVQNLNSV--NISGATSQLAFSSSVTNS---------------THS-LLPSLENSGYFSGSY-SS-FPSNPVNSGPNHDFSALR-TSPYHCAMNTEKARLLTFQM-WPLT---F
B_taurus_ENSBTAP00000034604               LYPSCSFVQNLNSI--NVSGASSQPTFHYSLTNS---------------THS-LLPSLENSGYFSGSY-SS-FPSNLLNSGPNQDFSALR-ISSYPCAMNTEKARLLTFQM-WPLT---F
R_norvegicus_ENSRNOP00000007702           LYPSCSFVQTLNPA--NSLEASPQPPLPSTATST---------------MPS-GFAASESTGYFSGSY-SS-FPSDPVNFRANQDCPAFS-TSPYHFAMNTEKARLLTYQT-WPLS---F
M_musculus_ENSMUSP00000013949             LYPSCNFVQTLNPA--NSLEASPRPSLPSTAMST---------------MPL-SFASSENTGYFSGSY-SS-FPSDPVNFRANQDCPALS-TSPYHFAMNTEKARLLTYET-WPLS---F
M_domestica_ENSMODP00000000728            LYPSCAFIQNLISV--N--LGSSQSTFSSSVNNA---------------TRS-LSLSSEQSGYFSGSY-SS-FPLEPVTSRGVEDLSPLN-TSPYSYSMSTEEARILTYQA-WPLT---F
C_familiaris_ENSCAFP00000022282           LYPSCSFIQNLSAV--STVGAASQPPAPLSEARS---------------THA-QSPGLERSSYFSASY-SS-FPVDPVDFRPSPAMSPWR-AGPSCVTMKSEEDRLCTFQG-WPLA---F
E_caballus_ENSECAP00000000598             LYPSCSFIQNLVSV--TSLESTSKNTSSPMRNSF---------------THS-LSPTLEHSGSFSGSY-SN-LSPNLVNSRAVEDFSPLR-TNPYSYAMSTEEARFLTYHM-WPLT---F
C_familiaris_ENSCAFP00000022277           LYPSCSFIHSLVSL--TSRDSTSKNI-SAMRNSF---------------THS-ISPTLEH-GSFSGSH-SN-LAANPVSSRAGEDFSPLS-TNPYSYAMSTEEARFLTYHM-WPLT---F
O_anatinus_ENSOANP00000016616             LYPSCSFIQNLLQT--HNPGASSYSAFCPPPLGS------------LSPTAT-ISPSLEPSGYFSGSF-SS-FPLDPVTSRAIEDLSQPR-PHVDNSAMSSEEARICTFQS-WPLT---F
T_guttata_ENSTGUP00000013125              LYPRCSFVQRMLSD--NNVGLSSRSAFSPSIANS---------LPPSLHSIA-LSPSLEQVGYFSGSF-SS-FPQDPVTTRAAEDLSFLS-PKLHNNSMRTEDARLCTFQS-WPLT---F
P_pygmaeus_ENSPPYP00000004357             LYPSCSFIQNLVS---ASLGSTSKNT-SPMRNSF---------------AHS-LSPTLEHSSLFSGSY-SS-LSPNPLNSRAVEDFSSSR-TNPYSYAMSTEEARFLTYHM-WPLT---F
M_mulatta_ENSMMUP00000004536              LYPSCSFIQNLVS---ATLGSTSKNT-SPMRNSF---------------AHS-LSPTLEHSSLFSGSY-SS-LSPNPLNSRAVEDLSPSR-TNPYSYAMSTEEARFLTYHM-WPLT---F
H_sapiens_ENSP00000227758                 LYPSCSFIQNLVS---ASLGSTSKNT-SPMRNSF---------------AHS-LSPTLEHSSLFSGSY-SS-LSPNPLNSRAVEDISSSR-TNPYSYAMSTEEARFLTYHM-WPLT---F
P_troglodytes_ENSPTRP00000007251          LYPSCSFIQNLVS---ASLGSTSKNT-SPMRNSF---------------AHS-LSPTLEHSSLFSGSY-SS-LSPNPLNSRAVEDISSSR-TNPYSYAMSTEEARFLTYHM-WPLT---F
G_gallus_ENSGALP00000035646               VYPSCSFVQNMLSL--NNLGLSTHSAFSPLVASN---------LSPSLRSMT-LSPSFEQVGYFSGSF-SS-FPQDPVTTRAAEDLSHLR-SKLHNPSMSTEEARLRTFHA-WPLM---F
R_norvegicus_ENSRNOP00000014560           FYPSCSFVQTLLS---GGLQSAAKNT-SPAKSRF---------------AHS---LPLEQ----GGIH-SS-LPSNPLNSRAVEDFS-LR-MNPCSYAMSTEEARFLSYSM-WPLS---F
M_musculus_ENSMUSP00000091422             FYPSCSFVQTLLS---ASLQSPSKNM-SPVKSRF---------------AHS---SPLER----GGIH-SN-LCSSPLNSRAVEDFS-SR-MDPCSYAMSTEEARFLTYSM-WPLS---F
A_carolinensis_ENSACAP00000012475         LYPSCSVVQNLTSL--NNLGSSFYSAFSPPSLSV---------GHSSSHSPQ-QTPNLDQVGYFSGSF-SS-VPQEL--PKLTEGISHVR-PKVANSAMSSEEARLLTFKT-WPLT---F
O_cuniculus_ENSOCUP00000011948            LYPSCSFIQNLVS---ASLDSTIKNT-SPVRSSF---------------AHS-LSPTVEPGGSFSGSY-SS-LSANPLNSRTVEDFSPLR-TNPYSYSMSSEEARFLTYHM-WPLS---F
M_domestica_ENSMODP00000000705            LFPSCAFIQNLTSV--NNLESNSQSALSSSLNSA---------------SCS-LSPSSEQSGYFSGSY-SS-FPLEPVTSRGVEDLSPLN-TSPYSYSMSTEEARILTYQA-WPLT---F
O_cuniculus_ENSOCUP00000008710            LYPSCSFVQSLNSV--NNWEANSRSTFPSSVTNS---------------THS-FLPSWEHSGYYSGSY-SS-LPSNPVNSRANQDFSAFR-VSPYHSAMSTEKARLLTFQS-WPLT---F
X_tropicalis_ENSXETP00000048002           LYPSCSFIQNVPSV---NLGASLYSAFSPPASNS---------TP----MHA-ASAENDKVEAITLKY-SS-IPQDPVTLRGIEDLSHVR-ISEY---MYTEEARLNSFQE-WSNM---F
T_nigroviridis_ENSTNIP00000012883         LSPSCTFIQSLPST--SNLLSSSHSAFSPLRIAPAIPLSG---AGPAVPNPS-ANPGEEPVGYLNMGF-SAPPPSSPLGSRGVEDMSHQR-PTCHNPNMRREQDRLDSFHS-WTLT---I
T_rubripes_ENSTRUP00000043752             LSPSCSFIQSLPST--SNLLSSSHSAFSPLRIAPAIPLSG---AGPAVPNPS-ANQGEEPVGYLNMGF-SAPPPSSPLISRGVEDMSHQR-PTCHNPNMRREQDRLESFHS-WTLT---I
G_aculeatus_ENSGACP00000027283            LSPTCSFIQSLPST--TNLLSSSHSAFSPLRIAPAV--------------PA-VSQGEEPVGYLNMGF-SAPPPSSPLSSRGVEDMSHQR-PTCHNPSKRKEQDRLDSFHP-WTLS---I
D_rerio_ENSDARP00000065554                LSPNCSFIQSLPAT--ANLLSSSHSAFSPLRNVAVLQLSAPATAAPSTTAPSTSGQTEEQVGYLNMGF-TNLAPSSPISSRGVEDMSHQRPPACHNPGMRREQERLDTFQN-WTLA---T
O_latipes_ENSORLP00000006992              LSPTCPFIQSLPST--TNLLSSSHSAFSPLRIAQAMPVSSERRQGPAASNPS-GGQSEEAVGYLNMAF-SAPPPSSPLASRGVEDLSHQR-PTCHNPSMRREQDRLDSFQP-WAIS---I
G_gorilla_ENSGGOP00000005705              LYPSCRFVQSLNSV--NNLEATSQPTFPSSVTNS---------------THS-LLPGTENSGYFSGSX-SN-SPSNPVNSRANQDFSALM-RSSYHCAMNNENARLLTFQT-WPLT---F
O_cuniculus_ENSOCUP00000014265            LYPSCSFSQNLISV---SLESPLRSSF----------------------AHP-LFPTQGPCVSFSGSY-PS-LSANPPNLTSV-DFSPLR-TS-LGYSMSTEEAR---FYY-KPFS---F
G_gorilla_ENSGGOP00000008137              ------------------------------RNSF---------------AHS-LSPTLEHSSLFSGSY-SS-LSPNPLNSRAIEDISSSR-TNPYSYAMSTEEARFLTYHM-WPLT---F
B_taurus_ENSBTAP00000046955               ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075338                -------------------------------------------------------------------------------------------------GMRSEEERLQTFHN-WPSDA--A
H_sapiens_ENSP00000360242                 VSPNCRFINGFYLENSA-TQSTNSGIQNGQYKV--------------------ENYLGSRDHFALDRP-SETHADYLLRTGQVVDISDT--IYPRNPAMYSEEARLKSFQN-WPDYA--H
C_familiaris_ENSCAFP00000034255           VSPNCRFINGFYFENTA-AQPTNPGIQNGQYNA--------------------ENYLRNRDHFVLDRP-SETHADYLLRTGQVVDISDT--TYPENPAMYSEEARLNSFQN-WPDYV--H
P_pygmaeus_ENSPPYP00000023167             VSPNCRFINGFYLENSA-TQSTNSGIQNGQYKV--------------------ENYLGSRNHFALDRP-SETHADYLLRTGQVVDISDT--IYPRNPAMYSEEARLKSFQN-WPDYA--H
M_musculus_ENSMUSP00000110746             ISPNCRFINGFYFENGA-AQSTNPGIQNGQYKS--------------------ENCVGNRNPFAPDRP-PETHADYLLRTGQVVDISDT--IYPRNPAMCSEEARLKSFQN-WPDYA--H
P_troglodytes_ENSPTRP00000038304          VSPNCRFINGFYLENSA-TQSTNSGIQNGQYKV--------------------ENYLGSRNHFALDRP-SETHADYLLRTGQVVDISDT--IYPRNPAMYSEEARLKSFQN-WPDYA--H
O_cuniculus_ENSOCUP00000008505            VSPNCRFINGFYFENSA-AQSTNPGVQNGQYKG--------------------ENYLGNRNHFALDRP-SETHADYLLRTGQVVDISDT--IYPRNPAMCSEEARLKSFQN-WPDYA--H
E_caballus_ENSECAP00000017630             VSPNCRFINGFYFENNA-AQPTNPGVQNGQYKV--------------------ENYLGNRNHFVLGRP-SETHAEYLLRTGQVVDISDT--IYPRNPAMCSEEARLKSFQN-WPDYA--H
T_guttata_ENSTGUP00000003825              LAPTCKFITESAFLKSD----MDPVAQNYQNRT--------------------ENGTSNSALPCALDD-PDVEADYLLRTRQVVDMSDS--LYPKNPAMCSEETRLKSFHN-WPLND--R
B_taurus_ENSBTAP00000053449               VSPNCRFINGFYFENNA-AQPTYSGVQNGQYKA--------------------ENYLGNRNHFVLERP-SETHAHYLLRTGQVVDLSDT--VYPRNPVMCSEEARLKSFHN-WPDYA--H
G_gallus_ENSGALP00000038337               LSPDCRFITGSAFLENN----VHPLVQSHQHRT--------------------ENGSSNLALPSALEDLSDVEADYLLRTRQVVDMSDT--LYPKNPAMCSEEARLKSFHN-WPPYG--L
R_norvegicus_ENSRNOP00000009358           ISPNCRFINGFYFENGA-TQSTSPGIQNGQYKS--------------------ENCVGNRNHFALDRP-SETHADYLLRTGQVVDISDT--IYPRNPAMCSEEARLKTFQN-WPDYA--H
C_intestinalis_ENSCINP00000000045         HRSNCEFILGQDCGNQPIGSQNISVQQTARPVPAGMIM---------------KSGPSEFRFTFVILT-FLTLYSTRPKVELATIASPYHEQLVRSLDLRKESDRFKTYEN-WPAQN-RT
X_tropicalis_ENSXETP00000030727           LYPSCSFIQNVPSV---NLGASLYSAFSPPASNS---------TP----MHA-ASAENDKVEAITLKY-SS-IPQDPVTLRGIEDLSHVR-ISEY---MYTEEARLNSFQE-WSNM---F
T_nigroviridis_ENSTNIP00000006583         --------------------------------------------------------------------------------------------------MRREKDRIRTFRE-WPADA--A
M_domestica_ENSMODP00000018715            VSPNCRFINGFYFEKNA-TRFPNPIIQNCQYRV--------------------ENCSRNRNHFALERP-SETHGEYLLRTGQVIDMSDT--IYPRNPSMCSEEARLRSFQN-WPDYA--H
X_tropicalis_ENSXETP00000035327           ISPNCKFINGFNNLRSDCILTQVPVMQNG--------------------------FQNSAEDLAERSS-SEIMADYLLRTGRVVDMSTP--KYPRHMEMCSEEARLQTFQN-WPAYS--P
C_intestinalis_ENSCINP00000009820         HRNNCELVNGNGSGNQPIAGDDFKSTISPLCECKA------------------LSMVLKTPKIQGCRK-FSMPLSFFVRIELATIASPYHEQLVRSLDLRKESDRSKTYEN-WPAQN-RT
T_rubripes_ENSTRUP00000011958             ----------------------------------------------------------------------------------ML----------EEPRMRREGDRIRTFQE-WPADA--A
G_aculeatus_ENSGACP00000003419            ----------------------------------------------------------------------------------MTDDRGTAPRAPEAPRMRGEGERLRTFGR-WPADA--P
C_intestinalis_ENSCINP00000005161         HRSNCEFIQGHDCGNIPIGLHCVVKYKLLMELTIPIFLGSWGWIR--------PDNTARENFMNVTYL-NLGEKNFFQRIELATISSVYHEQVLRSLDLKKEGERMKSFEN-WPTQN-RT
O_latipes_ENSORLP00000010149              VSPSCTFLRCTHFNRFK------------------------------------SNPHMPLSNGGLHDG-TEGYIDYQLRTRAIVDET----PYPRNRNMKSEEARLETFSS-WPRSA--P
X_tropicalis_ENSXETP00000029187           ----------------------------------------------------------------------------------------------VPPNMRSEAERQRSFRA-WPHTC-RT
A_carolinensis_ENSACAP00000011315         IFPECRFINDIDIGRNN-----TYSLLNCQHASEN------------------GSASTSQQQPSLDES-SDLDADYLLRTGQVVDLSGS--LYPRNPAMCSEEARLRTFHN-WPPYA--P
D_melanogaster_FBpp0086432                SSPICSMVLAPNHCGN-----------------------------------------------------VPRSQESDNEGNSVVDSP----ESCSCPDLLLEANRLVTFKD-WPNP---N
G_gorilla_ENSGGOP00000008442              VSPNCRFINGFYLENSA-TQSTNSGIQNGQYKV--------------------ENYLGSRNHFALDRP-SETHADYLLRTGQVVDISDT--IYPRNPAMYSEEARLKSFQN-WPDYA--H
O_anatinus_ENSOANP00000006435             ISPNCRFVNGCHFKNCA-LPLANASLQNGELGQV-------------------EECPGNPSHHALERS-SETHSDYLLRTRQVVDLSDT--VFPKNPAMCSEEARLETFQN-WPEYT--L
T_rubripes_ENSTRUP00000010298             VSPFCKFLSCIYRTSSN------------------------------------PIPGTSLTNGSAYNE-EAEDMEYRLRTGQVVDES----IYPVVPHMRSEESRLHTFST-WPLTA--P
A_aegypti_AAEL006633-PA                   -------------------------------------------------------------------------------------------------ELKREEHRLATYVN-WPIS---H
O_latipes_ENSORLP00000012199              ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000013586                ASPDCRFLSCAHGMRNS------------------------------------NSIQSP-----DYDE-EAENREFLLRTGEVVDES----MYPVVPHMKSEEARLSTFNN-WPADS--P
G_gallus_ENSGALP00000009239               LRATC--------------------------------------------------------------------------------------CHLFNYSMRDEARRLRTFSQ-WPRSS--P
T_nigroviridis_ENSTNIP00000018867         VSPVCQFLSCIYGTRPH------------------------------------QLIDASLANNSAYNE------------EAVVDES----IYPVAPHMKSEKSRLQTFSS-WPSAV--P
T_guttata_ENSTGUP00000007779              PRAAR--------------------------------------------------------------------------------------RRLFEASMRSVARRLRTFQQ-WPRTA--P
C_intestinalis_ENSCINP00000002256         HRSNCEFILGQDCGNQPI-DHMVWLQVVCSATLCDHLV---------------QLGQG-------------------------------------------------------------G
G_aculeatus_ENSGACP00000024474            VSPSCIFLSCTQRTNFN------------------------------------LSCENRLTNGFSYNE-EEEDLEYRLRRGEVVDES----TYPMAPHMKSEEARLQTLST-WPSSS--P
M_domestica_ENSMODP00000021022            ------------------------------------------------------------------------------------------------------------------------
X_tropicalis_ENSXETP00000057704           TFPECPYLQELKAKGEWKDCHYEPGLGSNILMEKP------------------LGDLSDERRRLETFR-GHSGLFPYNRVKFLAIQSPNILGKKSHYDMTNMYSRADTYRG-HHKHFLPY
P_troglodytes_ENSPTRP00000019640          ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000024483           LRPQCEFLSGKDVGNIG-------------------------------------------------------------KYDIRVKNPETLP-RGGRARYHEEEARLESFED-WPFYA-HG
C_intestinalis_ENSCINP00000000487         ----------------------------------------------------------------------------------------------MSIELFKEENRRETFKT-WSAAF-ND
H_sapiens_ENSP00000321377                 ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000004317               FHPDCEFLLGKDVGNIA-------------------------------------------------------------KYDVRVQKPENTLRRDDKARYQEEKARLESFKN-WPFYA-QG
M_musculus_ENSMUSP00000112867             LRPECEFLQGKDVGNIG-------------------------------------------------------------KYDIRVKSPEKML-RGGKARYHEEEARLESFED-WPFYA-HG
M_musculus_ENSMUSP00000058611             LRPECEFLQGKDVGNIG-------------------------------------------------------------KYDIRVKRPEKML-RGGKARYHEEEARLESFED-WPFYA-HG
G_gorilla_ENSGGOP00000008152              ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007294-PA                   ---------------------------------------------------------------MAHALSLPAPPIDLPDNKHKDDD----LACMSPEYFHIEENRLRSFTSRWPVT---F
M_musculus_ENSMUSP00000113890             LRPECEFLLGKDVGNIG-------------------------------------------------------------KYDIRVKSPEKML-RGDKARYHEEEARLESFED-WPFYA-HG
X_tropicalis_ENSXETP00000016312           SFPHCPYMQKLRDEGDGKENQSKV---------------------------------------------CAGPIKEGESGTTVPLSSSSNLEKKPCGYMSDEYSRLESYRG-HGQHF-NY
H_sapiens_ENSP00000217169                 ------------------------------------------------------------------------------------------------------------------------
P_troglodytes_ENSPTRP00000023641          ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000021651         HKPDCVFFNSLSQTVND---------------------------------------------TNISTP-NHQDMNHFVNTNPTEVVFET--MLLKRLTHKSIKLNIRTFDY-WPHQL-RE
P_troglodytes_ENSPTRP00000048273          FHPDCGFLLNKDVGNIA-------------------------------------------------------------KYDIRVKNLKSRL-RGGKMRYQEEEARLASFRN-WPFYV-QG
C_intestinalis_ENSCINP00000020067         ----------------------------------------------------------------------------------MAEIDRQDITGLASPSLTQHKEAKT------------Q
M_mulatta_ENSMMUP00000012096              ------------------------------------------------------------------------------------------------------------------------
H_sapiens_ENSP00000194097                 FHPDCGFLLNKDVGNIA-------------------------------------------------------------KYDIRVKNLKSRL-RGGKMRYQEEEARLASFRN-WPFYV-QG
C_intestinalis_ENSCINP00000000466         HKPDCEFANGTDTTNVP--------------------------------------------------------------------------LLRHKIQQNLPSLQNASFVQSIPNQDQTT
P_pygmaeus_ENSPPYP00000017359             FHPDCGFLLNKDVGNIA-------------------------------------------------------------KYDIRVKNLKSRL-RGGKMRYQEEEARLASFKN-WPFYV-QG
G_gorilla_ENSGGOP00000007398              ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000104503             -----------------------------------------------------------------------------------------------------------------------M
M_musculus_ENSMUSP00000022142             LRPECEFLQGKDVGNIG-------------------------------------------------------------KYDIRVKSPEKML-RGGKARYHEEEARLESFED-WPFYA-HG
P_pygmaeus_ENSPPYP00000012543             ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000010449         HLPDCEHLHSLQPNRNNHANTPVQSGLSRPNENA---------------------------------------------------------TFRSLPTRRPAHSNVHSSSS-LPRQP-TT
C_intestinalis_ENSCINP00000000510         ----------------------------------------------------------------------------------------------MSIELFKEENRRETFKT-WSAAF-ND
X_tropicalis_ENSXETP00000016315           FFPHCSYVQGLSIRHSY----------------------------------------------------------FMEEGVGPGFLDTNILGKE--GDMSDEYSRIQSYQA-VKEHF-PN
X_tropicalis_ENSXETP00000034890           SFPDCAYVQEQRAQTTGTQDQSQV---------------------------------------------CPMPIKEGESGIPARYSGSHNPGEKPLGDMNDEYSRLETYRG-HSQYF-PM
E_caballus_ENSECAP00000017749             ------------------------------------------------------------------------------------------------------------------------
C_familiaris_ENSCAFP00000018803           ------------------------------------------------------------------------------------------------------------------------
A_carolinensis_ENSACAP00000009897         YWSQCAFILGKEVGNIP-------------------------------------------------------------KYEIRVLYPRR---RYSGVTYKHLESRLQSFAD-WPSYA-RE
A_aegypti_AAEL009074-PA                   -------------------------------------------------------------MAGVMMAQVLSTPRDFTDNKVKEDNAYGHTATSVPISYHTEVARLESFRG-WMVS---F
E_caballus_ENSECAP00000002314             LRPDCGFLLGEDVGNVA-------------------------------------------------------------KYEVRVRKPPGTL-RGDAARYREEEARLKSFKD-WPFYA-QA
D_melanogaster_FBpp0075254                -------------------------------------------------------------------------FDQVDNNTNATQLFKNNINKTRMNDLNREETRLKTFTD-WPLD---W
A_carolinensis_ENSACAP00000005440         ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000011648         ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007292-PA                   ------------------------------------------------------------------------------MESHDNTERQERTGLCNELNYNQEINRLRTYFPLWTVP---Y
A_gambiae_AGAP007293-PA                   ------------------------------------------------------------------------MASAVVSCICREIAEYRVTHDTPEECLNYEVNRLRTFPL-WTVP---Y
A_gambiae_AGAP007291-PA                   ------------------------------------------------------------------------MASTVVSCICREIAEYRVTHIVPEECLNYEINRLRTYDLLWTVP---Y
O_cuniculus_ENSOCUP00000002871            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002312         ------------------------------------------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000040836              ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000013345         VLSNLQVFNIENNRITELPDSIGDLKK--------------------------LQSLLAKDNQLNSLP-TTISGMESLRTLDISGTNKVLYLPKTLCKVRTLEVLVLSNPAVM-EYPHSM

                                                  250       260       270       280       290       300       310       320       330       340       350       360
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000376897                 LSPTDLAK--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDT----------------------------------------------------
P_troglodytes_ENSPTRP00000007250          LSPTDLAK--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDT----------------------------------------------------
M_mulatta_ENSMMUP00000004533              LSPTDLAK--------AGFYYVGPGDRV-ACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDT----------------------------------------------------
P_pygmaeus_ENSPPYP00000004355             LSPTDLAK--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQDT----------------------------------------------------
E_caballus_ENSECAP00000010270             LSPTDLAK--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDDAMSEHLRHFPNCPFVENQFEDT----------------------------------------------------
B_taurus_ENSBTAP00000034604               LSPTDLAK--------AGFYYIGPGDRV-ACFACGGTLSNWEPKDDAMSEHLRHFPNCPFLGNQLQGT----------------------------------------------------
R_norvegicus_ENSRNOP00000007702           LSPAELAK--------AGFYYTGPGDRV-ACFACGGKLSNWDRKDDPLSEHRRHFPSCPFLKDVGQFT----------------------------------------------------
M_musculus_ENSMUSP00000013949             LSPAKLAK--------AGFYYIGPGDRV-ACFACDGKLSNWERKDDAMSEHQRHFPSCPFLKDLGQSA----------------------------------------------------
M_domestica_ENSMODP00000000728            LSPLDLAR--------AGFYYIGPGDMV-ACFACGGKLSNWEPKDDAMSEHRRHFPHCPFLESQIQET----------------------------------------------------
C_familiaris_ENSCAFP00000022282           PLPSALAR--------AGFYYVGPGDRV-ACFACGGKLSNWEPDDDALSEHLRHFPDCPFVEGQLQAT----------------------------------------------------
E_caballus_ENSECAP00000000598             LSPSELAR--------AGFYYIGPGDRV-ACFACGGTLSNWEPKDDAMSEHRRHFPNCPFLENSL-ET----------------------------------------------------
C_familiaris_ENSCAFP00000022277           LSPSDLAR--------AGFYYIGPGDKV-ACFACGGTLSNWEPKDDAMSEHRRHFPNCPFLENSL-ET----------------------------------------------------
O_anatinus_ENSOANP00000016616             LSPSALAK--------AGFYYTGPGDRV-ACFTCGGKLSNWEPKDDAMSEHRRHFPGCPFLERQTRDA----------------------------------------------------
T_guttata_ENSTGUP00000013125              LSPTDLAK--------AGFYYLGTADKV-ACFTCGGQLYNWEPKDNAVSEHRRHYPNCPFVENLIRDQ----------------------------------------------------
P_pygmaeus_ENSPPYP00000004357             LSPSELAR--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSL-ET----------------------------------------------------
M_mulatta_ENSMMUP00000004536              LSPSELAR--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSL-ET----------------------------------------------------
H_sapiens_ENSP00000227758                 LSPSELAR--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSL-ET----------------------------------------------------
P_troglodytes_ENSPTRP00000007251          LSPSELAR--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSL-ET----------------------------------------------------
G_gallus_ENSGALP00000035646               LSPAELAK--------AGLYYLGTADKV-ACFTCGGQLSNWEPKDNAMSEHRRHFPNCPFVENLMRDQ----------------------------------------------------
R_norvegicus_ENSRNOP00000014560           LSPAELAK--------AGFYYTGPGDRV-ACFACGGKLSNWEPNDDPLSEHRRHFPHCPFLENTS-ET----------------------------------------------------
M_musculus_ENSMUSP00000091422             LSPAELAR--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDDAMSEHRRHFPHCPFLENTS-ET----------------------------------------------------
A_carolinensis_ENSACAP00000012475         LSPSSLAK--------AGFYYIGPADKV-ACFVCGGHLGNWEPKDNAMSEHRRHFPTCPFVE-QTQSQ----------------------------------------------------
O_cuniculus_ENSOCUP00000011948            LSPSELAR--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDDAMSEHRRHFPKCPFLENSL-ET----------------------------------------------------
M_domestica_ENSMODP00000000705            LSPLDLAR--------AGFYYIGPGDMV-ACFACGGKLSNWEPKDDAMSEHRRHFPHCPFLESQIQET----------------------------------------------------
O_cuniculus_ENSOCUP00000008710            LSPMDLAK--------AGFYYVGPGDRV-ACFACGGKLSNWEPKDDAMSEHLRHFPNCPFVENQLQDA----------------------------------------------------
X_tropicalis_ENSXETP00000048002           LTPAELAK--------AGFYFVGPGDKV-ACFTCDGKLNNWEPNDNAMSEHRRHFPNCPFVKSSTRVS----------------------------------------------------
T_nigroviridis_ENSTNIP00000012883         ITPAELAK--------AGFYYLSQGDRV-ACFSCGGQLNNWEPGDRAMSEHQRHYPNCRFVRGDRADN----------------------------------------------------
T_rubripes_ENSTRUP00000043752             ITPAELAK--------AGFYYLSQGDRV-ACFSCGGQLSNWEPGDRAMSEHQRHYPNCRFVRGDRADN----------------------------------------------------
G_aculeatus_ENSGACP00000027283            ITPSELAK--------AGFYYLGQGDRV-ACFSCGGQLSNWEPGDRAVSEHQRHYPNCRFLSS---------------------------------------------------------
D_rerio_ENSDARP00000065554                VTPAELAK--------AGLYYLGQGDRV-ACFSCGGQLGSWEPGDRAVSEHQRHYPNCRFVRGDRADN----------------------------------------------------
O_latipes_ENSORLP00000006992              ITPAELAK--------AGFYYLGQNDRV-ACFSCGGQLSNWEPGDRAVSEHQRHYPNCRFVRGDRADN----------------------------------------------------
G_gorilla_ENSGGOP00000005705              LSPTDLAK--------AGFYYIGPGDRV-ACFXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX----------------------------------------------------
O_cuniculus_ENSOCUP00000014265            LLPSEFAR--------AGFSNVAPGDAV-AGFACDRKQSNWK-KDDAMLE-WRHVPN-PFLEI---------------------------------------------------------
G_gorilla_ENSGGOP00000008137              LSPSELAR--------AGFYYIGPGDRV-ACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSL-ET----------------------------------------------------
B_taurus_ENSBTAP00000046955               ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075338                VSPEELAR--------AGFHYLGYGDTV-QCFCCEGILRHWVDGDTPRGEHERHFPTCGLMRGRDVGNVP--RGSS--------------------------------------------
H_sapiens_ENSP00000360242                 LTPRELAS--------AGLYYTGIGDQV-QCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNL-N----------------------------------------------------
C_familiaris_ENSCAFP00000034255           LTPRELAS--------AGFYYTGIDDQV-QCFCCGGKLKNWEPCDNAWSEHRRHFPNCFFVLGRNV-N----------------------------------------------------
P_pygmaeus_ENSPPYP00000023167             LTPRELAS--------AGLYYTGIGDQV-QCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNL-N----------------------------------------------------
M_musculus_ENSMUSP00000110746             LTPRELAS--------AGLYYTGADDQV-QCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNV-N----------------------------------------------------
P_troglodytes_ENSPTRP00000038304          LTPRELAS--------AGLYYTGIGDQV-QCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNL-N----------------------------------------------------
O_cuniculus_ENSOCUP00000008505            LTPRELAS--------AGLYYTGIDDQV-QCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNV-N----------------------------------------------------
E_caballus_ENSECAP00000017630             LTPGELAS--------AGLYYTGIDDQV-QCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNV-N----------------------------------------------------
T_guttata_ENSTGUP00000003825              LTPQELAN--------AGFYYTGVGDQV-ACFCCGGKLKNWEPSDRAWSEHKRHFPKCLFVQGRDIGN----------------------------------------------------
B_taurus_ENSBTAP00000053449               LTPRELAR--------AGLYYTGIDDQV-QCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNI-N----------------------------------------------------
G_gallus_ENSGALP00000038337               LTPKELAS--------AGLYYTGVGDQV-ACFCCGGKLKNWEPGDRAWSEHKRHFPKCFFVLGRDVGN----------------------------------------------------
R_norvegicus_ENSRNOP00000009358           LSPRELAS--------AGLYYTGIDDQV-QCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNV-N----------------------------------------------------
C_intestinalis_ENSCINP00000000045         VYASDLAR--------SGFFYLGNLDRV-QCFSCGGVLRNWNYGDNITAEHRRHFPHCRFVRKKTVYQ----------------------------------------------------
X_tropicalis_ENSXETP00000030727           LTPAELAK--------AGFYFVGPGDKV-ACFTCDGKLNNWEPNDNAMSEHRRHFPNCPFVKSSTRVS----------------------------------------------------
T_nigroviridis_ENSTNIP00000006583         VAPADLAK--------AGFFFLGPRDAV-QCFCCGGILRCWVQGDSPGDEHRRHFPTCCFILGRAVGNIPLQAGSS--------------------------------------------
M_domestica_ENSMODP00000018715            LTPQELAS--------AGLYYMGFEDQV-QCFCCGGKLKNWEPCDRAMSEHKRHFPKCFFVLGRDVGN----------------------------------------------------
X_tropicalis_ENSXETP00000035327           LTPKELAN--------AGLFYTGINDQV-KCFCCGGKLMNWEPSDKAWTEHKKHFPECYFVLGRDVGN----------------------------------------------------
C_intestinalis_ENSCINP00000009820         VYASDLAR--------SGFFYLGNLDRV-QCFSCGGVLRNWNYGDNITAEHTRHFPHCSLFYAQ--------------------------------------------------------
T_rubripes_ENSTRUP00000011958             VAPADLAR--------AGFFFLGPGDAV-QCFCCGGILRCWMQGDTPGDEHRRHFPTCCFVLGKAVGNIPLQAGFS--------------------------------------------
G_aculeatus_ENSGACP00000003419            VTSGELAG--------AGFFYLGPGDEV-QCFCCGGVLKCWARGDRPAAEHRRHFPDCGFALGRPAGNVPLPAGSS--------------------------------------------
C_intestinalis_ENSCINP00000005161         VNPSDLAR--------SGFFYLGNLDRV-QCFSCGGVLRNWNYGDNITAEHRRHFPHCRMTQGTESNN----------------------------------------------------
O_latipes_ENSORLP00000010149              VRPRDLAQ--------AGLFYLGKEDKV-ECFSCGGKLSGWKPGDTPWNEHEKHFSHCFYILGHDVGN----------------------------------------------------
X_tropicalis_ENSXETP00000029187           VSPAELAR--------SGFYYLGPGDRV-QCFSCGGVLRSWEPGDRPDTEHRKFFPSCPFLQVRRGPP--------------------------------------------------GG
A_carolinensis_ENSACAP00000011315         VTPQDLAH--------AGLYYTGIGDQV-ECFCCGGKLKNWEPSDQAWSEHRRHFPRCFFVLGHDLNR----------------------------------------------------
D_melanogaster_FBpp0086432                ITPQALAK--------AGFYYLNRLDHV-KCVWCNGVIAKWEKNDNAFEEHKRFFPQCPRVQMGPLIE----------------------------------------------------
G_gorilla_ENSGGOP00000008442              LTPRELAS--------AGLYYTGIGDQV-QCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNL-N----------------------------------------------------
O_anatinus_ENSOANP00000006435             LSPGQLAR--------AGLYYSGIDDQV-ECFCCGGKLKNWEPCDRPWSEHKRHFPKCLFVLGRDVGN----------------------------------------------------
T_rubripes_ENSTRUP00000010298             VSPCDLAQ--------AGLYYLGQCDQV-QCFCCGGTLADWEIGDSAWAEHSKHFPFCFFILGHDVGN----------------------------------------------------
A_aegypti_AAEL006633-PA                   ISPSSLAK--------AGFYYTYNADQV-KCAWCEGVIGQWELGDDPFVEHQKFFPNCAKVISNGISSNPILDPTIGIQPV---------------------------------------
O_latipes_ENSORLP00000012199              ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000013586                VRPEDLAE--------AGMYYIGIDDNV-QCFCCGGGLSGWEQGDDPWSEHAKYYSNCFFFLGHNVGN----------------------------------------------------
G_gallus_ENSGALP00000009239               VSAWDLAK--------AGFFFVGPGDQV-QCFSCGGILKDWEPGDCPIVEHLKFFPFCKFIYHGAVWNQQ-VPLQGVF------------------------------------------
T_nigroviridis_ENSTNIP00000018867         VRPQDLAQ--------AGLYYLGQNDQV-QCFCCGGILANWDAGDSAWGEHNKHFPSCFFILGHDVGN----------------------------------------------------
T_guttata_ENSTGUP00000007779              VSARDLVE--------AGFFYLGPGDEV-QCFCCGGILKDWRPGDCPMIEHLHFFPSCKYLSGEDVGNQEMLSLQEIF------------------------------------------
C_intestinalis_ENSCINP00000002256         IYSETLA-----------------------------------------------------------------------------------------------------------------
G_aculeatus_ENSGACP00000024474            VRPRDLAQ--------AGLYYLGQSDRV-QCFCCGGMLAGWEVGDTAWEEHNKHFPNCFFMLGHDVGN----------------------------------------------------
M_domestica_ENSMODP00000021022            ---------------------VGPQDRV-QCFCCGGMLDNWMAGDSPILEHQRFFPKCQFALSKHTGNIPAQDTS---------------------------------------------
X_tropicalis_ENSXETP00000057704           MKEWDLAQ--------AGFYYVGPGDRV-RCISCGGELEKWERWDVPLTRHQHSFPHCPYMQKLRDEGDG--------------------------------------------------
P_troglodytes_ENSPTRP00000019640          ------------------------------------------------------------------------------------------------------------------------
R_norvegicus_ENSRNOP00000024483           TSPRVLSA--------AGFVFTGKRDTV-QCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSTE----------------------------------------------------
C_intestinalis_ENSCINP00000000487         EFVKELAR--------SGFFYLGNLDRT-QCFSCSGVLRNWRASDDVNVEHFRHFPHCKMGSNSESKNVPLPLD----------------------------------------------
H_sapiens_ENSP00000321377                 ------------------------------------------------------------------------------------------------------------------------
B_taurus_ENSBTAP00000004317               TSPRELSA--------AGFVFTGKHDTV-QCFSCGGCLGNWEDDDDPWKEHAKWFPKCEFLQSKKSLE----------------------------------------------------
M_musculus_ENSMUSP00000112867             TSPRALSA--------AGFVFTGKRDTV-QCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSE----------------------------------------------------
M_musculus_ENSMUSP00000058611             TSPRVLSA--------AGFVFTGKRDTV-QCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSE----------------------------------------------------
G_gorilla_ENSGGOP00000008152              ---------------------MGPKDSA-KCLHRGPQPSHWAAGDGPTQERGGPRSLGSPVLGLDTCRAW--------------------------------------------------
A_gambiae_AGAP007294-PA                   ISPNVLAR--------YGFYYVGTDDTV-KCYFCRVEIGLWEPQDDVIQEHLRWSPYCPLLKKRPTNNVPLNANYLDAV-PEPSFDTCG-----ISVRHNSLM-----------------
M_musculus_ENSMUSP00000113890             TSPRVLSA--------AGFVFTGKRDTV-QCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSPE----------------------------------------------------
X_tropicalis_ENSXETP00000016312           WNQQRLAKQTSDELAWAGFFYVGPGDRV-RCFSCGGEVDNWEPGDVPLTGHQLFFPHCSYVQGLSIRHSYFMEEG---------------------------------------------
H_sapiens_ENSP00000217169                 ---------------------MGPKDSA-KCLHRGPQPSHWAAGDGPTQERCGPRSLGSPVLGLDTCRAW--------------------------------------------------
P_troglodytes_ENSPTRP00000023641          -------------------------------------------------------------LGLDTCRAW--------------------------------------------------
C_intestinalis_ENSCINP00000021651         VNTAALAK--------YGFYYLGISDMV-ECFCCSNVLGNWNVDDNPKNRHLERFPNCRWVADVEVHQHPHL------------------------------------------------
P_troglodytes_ENSPTRP00000048273          ISPCVLSE--------AGFVFTGKQDTV-QCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSE----------------------------------------------------
C_intestinalis_ENSCINP00000020067         ILPGRNCC--------A-------SNSV-TAFDC--------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000012096              ---------------------MGPEDSA-KCPRHGPQLCRWAAGDGPARERCGPRSLGSPALGLDSCRAW--------------------------------------------------
H_sapiens_ENSP00000194097                 ISPCVLSE--------AGFVFTGKQDTV-QCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSE----------------------------------------------------
C_intestinalis_ENSCINP00000000466         LSAGELLK--------FGNIDQTTNQVV-------------TPRNLPVQQSSNQFGQMYQTATIHKPH----------------------------------------------------
P_pygmaeus_ENSPPYP00000017359             IPPCVLSE--------AGFVFTGKQDTV-QCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSE----------------------------------------------------
G_gorilla_ENSGGOP00000007398              ------------------------------------------------------------------------------------------------------------------------
M_musculus_ENSMUSP00000104503             FSPADLFR--------AAVFSMGPESRA-RDSVRGPELSHREDGSGRTQEQDKPHCPCNHVLGQ--------------------------------------------------------
M_musculus_ENSMUSP00000022142             TSPRVLSA--------AGFVFTGKRDTV-QCFSCGGSLGNWEEGDDPWKEHAKWFPKCEFLQSKKSSE----------------------------------------------------
P_pygmaeus_ENSPPYP00000012543             ---------------------MGPKDSA-KCLHCGPQPSHWAAGDGPAQEHCGPRSLGSPVLGLDTCRAW--------------------------------------------------
C_intestinalis_ENSCINP00000010449         ITINQPRI--------RSTFTIHEHSNI-DLFPC--------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000000510         EFVKELAR--------SGFFYLGNLDRT-QCFSCSGVLRNWRASDDVNVEHFRHFPHCKMGSNSESKNVPLPLD----------------------------------------------
X_tropicalis_ENSXETP00000016315           QTPIKLAW--------AGFYYVGPKEKV-RCFSCGGEMDEWWSREDPLTEHHRRFPQCHFILGRKEGNPPGKG-----------------------------------------------
X_tropicalis_ENSXETP00000034890           ANQRRLAQ--------AGFSYVGPGDQV-RCFSCGGELEKWERWDVPLTRHQHSFPHCHYIYGRKTGYIGIPLLRPL-------------------------------------------
E_caballus_ENSECAP00000017749             --------------------SMGPEDKA-KCWCRGLELSHQAAGGSPMQGHHRPHCLALSWGGR--------------------------------------------------------
C_familiaris_ENSCAFP00000018803           ---------------------MGPEDRA-KCWCRGPELGRGRLSPCGHTEGRDGRC-ARCWGGR--------------------------------------------------------
A_carolinensis_ENSACAP00000009897         AQPDLLAK--------AGFFFTGIKDTV-QCFACSGCLGNWEDGDDPWKEHAKWFPECEFLQKEKTRD----------------------------------------------------
A_aegypti_AAEL009074-PA                   ISKTELAR--------YGFYYVGPNDMV-KCYFCRVEIGLWEPNDNVLSEHLRWSPYCPLLRKRQTNNVPIDASFLDQL-PEPSYDTCG-----IRIRENSVAENAYSSSDR--------
E_caballus_ENSECAP00000002314             TAPRELSA--------AGFVFTGSRDAA-QCFSCGGCLGNWEDGDDPWKEHAKWFPKCEFLQSKKSSE----------------------------------------------------
D_melanogaster_FBpp0075254                LDKRQLAQ--------TGMYFTHAGDKV-KCFFCGVEIGCWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINAEALDRILPPISYDICGANDSTLEMREHAYAEGVIPMSQLIQSIGMNA
A_carolinensis_ENSACAP00000005440         ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000011648         ------------------------------------------------------------------------------------------------------------------------
A_gambiae_AGAP007292-PA                   IYPEELAR--------WGFFYTGYRDCV-RCYFCHIELGGWDEHDVVIEEHLKWSPDCRLMTKRPTDNVPVDANFLDQL------DTAG-------------------------------
A_gambiae_AGAP007293-PA                   IYPEELAR--------WGFFYTGYRDCV-RCYFCRIELGGWDEHDVVIEEHLKWSPHCRLMTKRPTNNVPIDPDFLDQL-GEIVPDTTG-------------------------------
A_gambiae_AGAP007291-PA                   IYPEELAR--------WGFFYTGHRDCV-RCYFCRIELGGWDEHDVVIEEHLKWSPHCRLMTKRPTNNVPIDPDFLDQL-GEIVPDTTG-------------------------------
O_cuniculus_ENSOCUP00000002871            ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000002312         ------------------------------MFRC--------------------------------------------------------------------------------------
M_mulatta_ENSMMUP00000040836              ------------------------------------------------------------------------------------------------------------------------
C_intestinalis_ENSCINP00000013345         VACEGLEAIQKFICKDTGIEYIPPSHATLKVLDSSATTSSSSSKQTAAANLQLYQSSMDQYQRSKDEKMKQQLEIERSIAEQQREQAYLTAKAKHEKAKENAFLKQEQAVFDRSISEQQK

                                                  370       380       390       400       410       420       430       440       450       460       470       480
                                          =========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+=========+
H_sapiens_ENSP00000376897                 -----------SR----------------------------------YTVSNLSMQTHAARFKTF-F---NWPS-SVLVNPEQLASAGFY------YVGNSDDV-----KCFCCDGGLRC
P_troglodytes_ENSPTRP00000007250          -----------SR----------------------------------YTVSNLSMQTHAARFKTF-F---NWPS-SVLVNPEQLASAGFY------YVGNSDDV-----KCFCCDGGLRC
M_mulatta_ENSMMUP00000004533              -----------SR----------------------------------YTVSNLSMQTHAARFKTF-F---NWPS-SVLVNPEQLASAGFY------YVGNSDDV-----KCFCCDGGLRC
P_pygmaeus_ENSPPYP00000004355             -----------SR----------------------------------YTVSNLSMQTHAARFKTF-F---NWPS-SVLVNPEQLASAGFY------YVGNSDDV-----KCFCCDGGLRC
E_caballus_ENSECAP00000010270             -----------SR----------------------------------YTVSNLSMQTHAARFRTF-C---NWPS-SVQVPPEQLASAGFY------YMGHSDDV-----KCFCCDGGLRC
B_taurus_ENSBTAP00000034604               -----------SR----------------------------------YTASNLSMQTYAARIKTF-C---SWPS-SVPVHPEQLASAGFY------YVGHSDDV-----KCFCCDGGLRC
R_norvegicus_ENSRNOP00000007702           -----------SQ----------------------------------YTVSNLSMQTHAARVRTF-S---TWPS-SALVHPQELASAGFY------YTGHSDDV-----KCFCCDGGLRC
M_musculus_ENSMUSP00000013949             -----------SR----------------------------------YTVSNLSMQTHAARIRTF-S---NWPS-SALVHSQELASAGFY------YTGHSDDV-----KCFCCDGGLRC
M_domestica_ENSMODP00000000728            -----------SR----------------------------------FNVSNLSMQTHAARVKTF-V---TWPP-QIPVHPEQLANAGFY------YVGRNDDV-----KCFCCDGGLRC
C_familiaris_ENSCAFP00000022282           -----------VR----------------------------------YTASNLSMQTLAARSRTF-C---NWPP-RAPVHPEQLASAGFY------YMGHSDDV-----KCFCCDGGLRC
E_caballus_ENSECAP00000000598             -----------LR----------------------------------FSISNLSMQTHAARLRTF-M---YWPP-RVPVQPEQLASAGFY------YVGRNDDV-----KCFCCDGGLRC
C_familiaris_ENSCAFP00000022277           -----------LR----------------------------------FSISNLSMQTHAARLRTF-V---YWPS-SVPVRPEQLASAGFY------YVGRNDDV-----KCFCCDGGLRC
O_anatinus_ENSOANP00000016616             -----------SR----------------------------------FNVSNASMQTHAARVKTF-L---NWPA-RIPVQPEQLASAGFY------YVGRNDDV-----KCFCCDGGLRC
T_guttata_ENSTGUP00000013125              -----------QS----------------------------------FNVSNVSMQTHEARVKTF-L---NWPT-RIPVQPEQLADAGFY------YVGRNDDV-----KCFCCDGGLRC
P_pygmaeus_ENSPPYP00000004357             -----------LR----------------------------------FSISNLSMQTHAARMRTF-M---YWPS-SVPVQPEQLASAGFY------YVGRNDDV-----KCFCCDGGLRC
M_mulatta_ENSMMUP00000004536              -----------LR----------------------------------FSISNLSMQTHAARMRTF-M---YWPS-SVPVQPEQLASAGFY------YVGRNDDV-----KCFCCDGGLRC
H_sapiens_ENSP00000227758                 -----------LR----------------------------------FSISNLSMQTHAARMRTF-M---YWPS-SVPVQPEQLASAGFY------YVGRNDDV-----KCFCCDGGLRC
P_troglodytes_ENSPTRP00000007251          -----------LR----------------------------------FSISNLSMQTHAARMRTF-M---YWPS-SVPVQPEQLASAGFY------YVGRNDDV-----KCFCCDGGLRC
G_gallus_ENSGALP00000035646               -----------PS----------------------------------FNVSNVTMQTHEARVKTF-I---NWPT-RIPVQPEQLADAGFY------YVGRNDDV-----KCFCCDGGLRC
R_norvegicus_ENSRNOP00000014560           -----------QR----------------------------------FSVSNLSMQTHSARMRTF-L---YWPS-SVLVQPEQLASAGFY------YVDHNDDV-----KCFCCDGGLRC
M_musculus_ENSMUSP00000091422             -----------QR----------------------------------FSISNLSMQTHSARLRTF-L---YWPP-SVPVQPEQLASAGFY------YVDRNDDV-----KCFCCDGGLRC
A_carolinensis_ENSACAP00000012475         -----------PG----------------------------------FTVSNLSMQTYRARVGTF-E---NWPM-TVPVLPQRLADAGFY------YVGRNDDV-----KCFCCDGGLRC
O_cuniculus_ENSOCUP00000011948            -----------LR----------------------------------FSISNLSMQTHASRMRTF-M---YWPS-SAPVGPEQLASAGFY------YVGRNDDV-----KCFCCDGGLRC
M_domestica_ENSMODP00000000705            -----------SR----------------------------------FNVSNLSMQTHAARVKTF-V---TWPP-QIPVHPEQLANAGFY------YVGCNDDV-----KCFCCDGGLRC
O_cuniculus_ENSOCUP00000008710            -----------SR----------------------------------YTISNLSMQTHAARFKTF-F---NWPS-SLLVHPEQLASAGFY------YVGHSDDV-----KCFCCDGGLRC
X_tropicalis_ENSXETP00000048002           -----------SR----------------------------------FSVSNVSMQASSARLKTF-A---SWPP-RIPISPTRLAEAGFY------YVGRNDDV-----KCFCCDGGLRC
T_nigroviridis_ENSTNIP00000012883         -----------ISLAGAVPGGLTSQLSGGVPTL--------------SNVSNPAMQQSEERLLTF-V---NWPS-RIPVRPDQLARAGFY------YVGRNDDV-----KCFCCDGGLRC
T_rubripes_ENSTRUP00000043752             -----------ISLAGAAPG-----------GL--------------TNVSNPAMQQSEERLLTF-V---NWPS-RIPVRPDQLAKAGFY------YVGRNDDV-----KCFCCDGGLRC
G_aculeatus_ENSGACP00000027283            ----------------------------GAAAL--------------NNVSNPAMQQSDERLLTF-V---NWPA-RIPVRPDQLAKAGFY------YVGRNDDV-----KCFCCDGGLRC
D_rerio_ENSDARP00000065554                -----------IPLSGG--------------GL--------------SNVSNSAMQQCEERLLTF-V---NWPS-RIPVRPDQLAKAGFY------YVGRNDDV-----KCFCCDGGLRC
O_latipes_ENSORLP00000006992              -----------VPLVAGA-TALSAAASSGALAL--------------TSVSNPSMQQSEDRRLTF-V---NWPS-RIPVRPEQLAKAGFY------YVGRNDDV-----KCFCCDGGLRC
G_gorilla_ENSGGOP00000005705              -----------XX----------------------------------XXXXXXXXXXXXXXXXXX-X---XXXX-XXXXXXXXXXXXXXX------XXXXXXXX-----XXXXXXXXXXX
O_cuniculus_ENSOCUP00000014265            -----------LR----------------------------------FSISNWSMQAH-AQMSTN-M---YWPS-SDPVCPEQLATVDFY------YVALSDDI-----KCFCCDGALR-
G_gorilla_ENSGGOP00000008137              -----------LR----------------------------------FSISNLSMQTHAARMRTF-M---YWPS-SVPVQPEQLASAGFY------YVGRNDDV-----KCFCCDGGLRC
B_taurus_ENSBTAP00000046955               ------------------------------------------------------------------------------------------------------------------------
D_rerio_ENSDARP00000075338                -DSVDDS----------------------------------------------EMETEDNRRSTF-H---NWPT-GAAVQPDTLARAGFF------YTGHGDNV-----KCFFCDGGLRN
H_sapiens_ENSP00000360242                 -----------IRSESDAVSSDRNFPNST------------------NLPRNPSMADYEARIFTF-G---TW---IYSVNKEQLARAGFY------ALGEGDKV-----KCFHCGGGLTD
C_familiaris_ENSCAFP00000034255           -----------IRSESDVASTDRNVPNST------------------SIPENPAMADYEARIVTF-R---MW---MCSINKEQLARAGFY------SLGDGDKV-----KCFHCGGGLTD
P_pygmaeus_ENSPPYP00000023167             -----------IRSESDAVSSDRNFPNST------------------NLPRNPSMADYEARIFTF-G---TW---IYSVNKEQLARAGFY------ALGEGDKV-----KCFHCGGGLTD
M_musculus_ENSMUSP00000110746             -----------VRSESG-VSSDRNFPNST------------------NSPRNPAMAEYEARIVTF-G---TW---TSSVNKEQLARAGFY------ALGEGDKV-----KCFHCGGGLTD
P_troglodytes_ENSPTRP00000038304          -----------IRSESDAVSSDRNFPNST------------------NLPRNPSMADYEARIFTF-G---TW---IYSVNKEQLARAGFY------ALGEGDKV-----KCFHCGGGLTD
O_cuniculus_ENSOCUP00000008505            -----------IRSESDVVSSDRNFPNST------------------NPPRNPAMADYEARIISF-G---TW---IYSVNKEQLARAGFY------ALGEGDKV-----KCFHCGGGLTD
E_caballus_ENSECAP00000017630             -----------IR