BRAF (Anolis carolinensis)
Description [+]
- Synonyms: BRAF
- Species: Anolis carolinensis
- Short gene description: B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1)(p94)(v-Raf murine sarcoma viral oncogene homolog B1) [Source:UniProtKB/Swiss-Prot;Acc:P15056]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: BRAF-A_carolinensis
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | RBD | 137 | 209 |
PFAM A | C1_1 | 217 | 265 |
PFAM A | Pkinase | 437 | 694 |
PFAM A | Pkinase_Tyr | 437 | 694 |
Protein sequence [+]
BRAF | Anolis carolinensis | 28377 | length:746
SLFNGDMEPELPPLPAAGGDPAVPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLE
AKAYEEYTSKLDALQQREQQLLESMGNGTDFSVSSSASTETVASSSSSSLSVAPSSLSVY
QNPTDLSRNNPKSPQKPTVRVFLPNKQRTVVPARCGVTVRESLKKALMMRGLIPECCAVY
RIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQG
FRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHRPISQEETSLGESTTACGSYS
SVVPSDLSGSTVLPSPSPSKSIPIPQPFRQGDEDHRNQFGQRDRSSSAPNVHINTIEPVN
IDDLIRDQGLRGEGGSTTGLSATPPASLPGSLTKALQKSPGPQRERKSSSSSDDRTRMKT
LGRRDSSDDWEIPDGQITVGQRIGSGSFGTVFKGKWHGDVAVKMLNVTAPTPQQLQAFKN
EVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDVARQT
AQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWM
APEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSK
VRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQT
EDFSLYACASPKTPIQAGGYGGFSVS
AKAYEEYTSKLDALQQREQQLLESMGNGTDFSVSSSASTETVASSSSSSLSVAPSSLSVY
QNPTDLSRNNPKSPQKPTVRVFLPNKQRTVVPARCGVTVRESLKKALMMRGLIPECCAVY
RIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQG
FRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHRPISQEETSLGESTTACGSYS
SVVPSDLSGSTVLPSPSPSKSIPIPQPFRQGDEDHRNQFGQRDRSSSAPNVHINTIEPVN
IDDLIRDQGLRGEGGSTTGLSATPPASLPGSLTKALQKSPGPQRERKSSSSSDDRTRMKT
LGRRDSSDDWEIPDGQITVGQRIGSGSFGTVFKGKWHGDVAVKMLNVTAPTPQQLQAFKN
EVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDVARQT
AQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWM
APEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSK
VRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQT
EDFSLYACASPKTPIQAGGYGGFSVS
Structure links:
- Smartdomain prediction information: SM00455
- Smartdomain prediction information: SM00109
- Smartdomain prediction information: SM00219
- Smartdomain prediction information: SM00220
- Prosite motif and domain information: PS00107
- Prosite motif and domain information: PS00108
- Prosite motif and domain information: PS00479
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0006468 | protein amino acid phosphorylation | biological_proccess | IEA |
GO:0007242 | intracellular signaling cascade | biological_proccess | IEA |
GO:0007165 | signal transduction | biological_proccess | IEA |
GO:0004672 | protein kinase activity | mollecular_function | IEA |
GO:0005524 | ATP binding | mollecular_function | IEA |
GO:0004713 | protein tyrosine kinase activity | mollecular_function | IEA |
GO:0004674 | protein serine/threonine kinase activity | mollecular_function | IEA |
GO:0005057 | receptor signaling protein activity | mollecular_function | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0005634 | nucleus | cell_component | IEA |
GO:0005737 | cytoplasm | cell_component | IEA |
GO:0005886 | plasma membrane | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSACAG00000011178
- Expression info from Arrayexpress [?] : ENSACAG00000011178
- Protein expression from Protein Atlas: [?] ENSACAG00000011178
Click on [?] for more information.