KGB-1 (Caenorhabditis elegans)
Description [+]
- Synonyms: KGB-1
- Species: Metazoa;Bilateria;Ecdysozoa;Nematoda; Caenorhabditis elegans
- Short gene description: kgb-1 encodes a serine/threonine kinase that is a member of the JNK (Jun-N-terminal kinase) subfamily of MAP (mitogen-activated protein)kinases. loss of kgb-1 activity results in temperature-sensitive sterility in hermaphrodites and males. in hermaphrodites, this sterility is associated with disorganized gonads and endomitotic oocytes that have likely failed to undergo oocyte maturation. in kgb-1 mutant males, sperm is present, but is non-functional. KGB-1 interacts in vitro with all four C. elegans germline helicases, GLH-1, -2, -3, and -4, that localize to P granules in vivo. Northern analyses indicate that kgb-1 mRNA is present in both somatic and germline tissues. [Source: WormBase]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: KGB-1-C_elegans
