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NEX-1   (Caenorhabditis elegans)

Description [+]
  • Synonyms: NEX-1,
  • Species: Metazoa;Bilateria;Ecdysozoa;Nematoda; Caenorhabditis elegans
  • Short gene description: nex-1 encodes an annexin, a member of a family of calcium-dependent phospholipid binding proteins. NEX-1 is required for efficient engulfment of apoptotic cell corpses in the pharynx, and may also function in other membrane fusion events, such as exocytosis. NEX-1 in vitro can bind phosphatidylserine, phosphatidylinositol, heparin, heparan sulfate, and chondroitin sulfate. NEX-1 is expressed in the pharynx, hypodermal cells, the vulva, the uterus, the spermathecal valve, and yolk granules of maturing oocytes. [Source: WormBase]
  • Family: other
  • Process: apoptosis,
  • Pathways: apoptotic cell clearance,
  • Criteria: manually curated
  • Curator comment: Null
  • Human ortholog(s): ANXA1 ANXA13 ANXA5 ANXA8 ANXA6 ANXA4 ANXA8L1 ANXA11 ANXA8L2 ANXA7
  • WIKI: NEX-1-C_elegans
References [+]
Structure & Sequence [+]
Evolution [+]
Information from other databases [+]