RIPK2 (Canis lupus familiaris)
Description [+]
- Synonyms: RIPK2
- Species: Canis lupus familiaris
- Short gene description: Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1)(RIP-like-interacting CLARP kinase)(Receptor-interacting protein 2)(RIP-2)(CARD-containing interleukin-1 beta-converting enzyme-associated kinase)(CARD-containing IL-1 beta ICE-kinase) [Source:UniProtKB/Swiss-Prot;Acc:O43353]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: RIPK2-C_familiaris
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | Pkinase | 18 | 290 |
PFAM A | Pkinase_Tyr | 18 | 290 |
PFAM A | CARD | 435 | 522 |
Protein sequence [+]
RIPK2 | Canis lupus familiaris | 9615 | length:540
MNREGPRCALPTIPCRKLADLRYLSRGASGTVSSARHADWRVQVAVKQLHIHSPLRDSER
NDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPL
RFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRTMSLSQSRT
SKSSPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVITWEVLSRKQPFEEVTNPLQIMY
SVSQGHRPNTNEESLPLDIPHRALMISLIESGWAQNPDERPSFLKCLIQLEPVLRTFEEI
TFLEAVIQLKKTKLQSALSTLHLCDKKEMESSLNIPVTHGPQEESCGSSQPHENSVSTGA
SESLSAPQDNNFLSRKTQDFSPVCHYPVNHSCNSNISAAQKWTFCDHKTTPCALTVINPF
SAEGNTERLQPGIAQQWIQSKREDIVSQMTEACLNQSLDALLSRDLIMKEDYELVSTKPT
RTSKVRQLLDTSDIQGEEFARIIVQKLKDNKQMGLQPYPEILVVSRSQPLNSFQNKNLKK
NDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPL
RFRILHEIALGVNYLHNMNPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRTMSLSQSRT
SKSSPEGGTIIYMPPENYEPGQKSRASVKHDIYSYAVITWEVLSRKQPFEEVTNPLQIMY
SVSQGHRPNTNEESLPLDIPHRALMISLIESGWAQNPDERPSFLKCLIQLEPVLRTFEEI
TFLEAVIQLKKTKLQSALSTLHLCDKKEMESSLNIPVTHGPQEESCGSSQPHENSVSTGA
SESLSAPQDNNFLSRKTQDFSPVCHYPVNHSCNSNISAAQKWTFCDHKTTPCALTVINPF
SAEGNTERLQPGIAQQWIQSKREDIVSQMTEACLNQSLDALLSRDLIMKEDYELVSTKPT
RTSKVRQLLDTSDIQGEEFARIIVQKLKDNKQMGLQPYPEILVVSRSQPLNSFQNKNLKK
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0006468 | protein amino acid phosphorylation | biological_proccess | IEA |
GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB cascade | biological_proccess | IEA |
GO:0034134 | toll-like receptor 2 signaling pathway | biological_proccess | IEA |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | biological_proccess | IEA |
GO:0032729 | positive regulation of interferon-gamma production | biological_proccess | IEA |
GO:0032743 | positive regulation of interleukin-2 production | biological_proccess | IEA |
GO:0032760 | positive regulation of tumor necrosis factor production | biological_proccess | IEA |
GO:0032496 | response to lipopolysaccharide | biological_proccess | IEA |
GO:0032755 | positive regulation of interleukin-6 production | biological_proccess | IEA |
GO:0032874 | positive regulation of stress-activated MAPK cascade | biological_proccess | IEA |
GO:0043330 | response to exogenous dsRNA | biological_proccess | IEA |
GO:0046330 | positive regulation of JNK cascade | biological_proccess | IEA |
GO:0050830 | defense response to Gram-positive bacterium | biological_proccess | IEA |
GO:0070374 | positive regulation of ERK1 and ERK2 cascade | biological_proccess | IEA |
GO:0032494 | response to peptidoglycan | biological_proccess | IEA |
GO:0050852 | T cell receptor signaling pathway | biological_proccess | IEA |
GO:0046641 | positive regulation of alpha-beta T cell proliferation | biological_proccess | IEA |
GO:0043065 | positive regulation of apoptosis | biological_proccess | IEA |
GO:0042098 | T cell proliferation | biological_proccess | IEA |
GO:0031663 | lipopolysaccharide-mediated signaling pathway | biological_proccess | IEA |
GO:0034142 | toll-like receptor 4 signaling pathway | biological_proccess | IEA |
GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway | biological_proccess | IEA |
GO:0070431 | nucleotide-binding oligomerization domain containing 2 signaling pathway | biological_proccess | IEA |
GO:0032722 | positive regulation of chemokine production | biological_proccess | IEA |
GO:0070555 | biological_proccess | IEA | |
GO:0070391 | response to lipoteichoic acid | biological_proccess | IEA |
GO:0033091 | positive regulation of immature T cell proliferation | biological_proccess | IEA |
GO:0004672 | protein kinase activity | mollecular_function | IEA |
GO:0005524 | ATP binding | mollecular_function | IEA |
GO:0004713 | protein tyrosine kinase activity | mollecular_function | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0004674 | protein serine/threonine kinase activity | mollecular_function | IEA |
GO:0050700 | CARD domain binding | mollecular_function | IEA |
GO:0030274 | LIM domain binding | mollecular_function | IEA |
GO:0005622 | intracellular | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSCAFG00000008959
- Expression info from Arrayexpress [?] : ENSCAFG00000008959
- Protein expression from Protein Atlas: [?] ENSCAFG00000008959
- entrezgene: 477936
Click on [?] for more information.