PRDX2 (Canis lupus familiaris)
Description [+]
- Synonyms: PRDX2
- Species: Canis lupus familiaris
- Short gene description: Peroxiredoxin-2 (EC 1.11.1.15)(Thioredoxin peroxidase 1)(Thioredoxin-dependent peroxide reductase 1)(Thiol-specific antioxidant protein)(TSA)(PRP)(Natural killer cell-enhancing factor B)(NKEF-B) [Source:UniProtKB/Swiss-Prot;Acc:P32119]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: PRDX2-C_familiaris
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | Redoxin | 8 | 163 |
PFAM A | AhpC-TSA | 9 | 142 |
PFAM A | 1-cysPrx_C | 152 | 195 |
Protein sequence [+]
PRDX2 | Canis lupus familiaris | 9615 | length:199
VMTSGKAHIGKPAPPFQATAVVDGAFKEVKLCDYKGKYLVLFFYPLDFTFVCPTEIIAFS
EHAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLVADVTRSLSEDYGVLK
EDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEVLRLVQAFQYTDEHGEVCPAGWKPG
SDTIKPNVDDSKEYFSKHN
EHAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLVADVTRSLSEDYGVLK
EDEGIAYRGLFIIDGKGVLRQITVNDLPVGRSVDEVLRLVQAFQYTDEHGEVCPAGWKPG
SDTIKPNVDDSKEYFSKHN
Evolution [+]
Explore tree at phylomeDB:   Click here.
DeathBase uses Jalview, an external application that requires Java. Please, check that you have the latest version of Java
installed and that Java is enabled in your browser. When correctly installed your browser should display the following examples properly. You can download the latest version of Java at Java Download Site.
Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
GO:0032088 | negative regulation of NF-kappaB transcription factor activity | biological_proccess | IEA |
GO:0032496 | response to lipopolysaccharide | biological_proccess | IEA |
GO:0006916 | anti-apoptosis | biological_proccess | IEA |
GO:0000187 | activation of MAPK activity | biological_proccess | IEA |
GO:0048538 | thymus development | biological_proccess | IEA |
GO:0048872 | homeostasis of number of cells | biological_proccess | IEA |
GO:0042743 | hydrogen peroxide metabolic process | biological_proccess | IEA |
GO:0042098 | T cell proliferation | biological_proccess | IEA |
GO:0045581 | negative regulation of T cell differentiation | biological_proccess | IEA |
GO:0042744 | hydrogen peroxide catabolic process | biological_proccess | IEA |
GO:0002536 | respiratory burst during acute inflammatory response | biological_proccess | IEA |
GO:0010310 | regulation of hydrogen peroxide metabolic process | biological_proccess | IEA |
GO:0010671 | negative regulation of oxygen and reactive oxygen species metabolic process | biological_proccess | IEA |
GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway | biological_proccess | IEA |
GO:0016209 | antioxidant activity | mollecular_function | IEA |
GO:0016491 | oxidoreductase activity | mollecular_function | IEA |
GO:0008379 | thioredoxin peroxidase activity | mollecular_function | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSCAFG00000017163
- Expression info from Arrayexpress [?] : ENSCAFG00000017163
- Protein expression from Protein Atlas: [?] ENSCAFG00000017163
- entrezgene: 484926
Click on [?] for more information.