CARD15 (Canis lupus familiaris)
Description [+]
- Synonyms: CARD15
- Species: Canis lupus familiaris
- Short gene description: Nucleotide-binding oligomerization domain-containing protein 2 (Caspase recruitment domain-containing protein 15)(Inflammatory bowel disease protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q9HC29]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: CARD15-C_familiaris
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | NACHT | 113 | 283 |
Protein sequence [+]
CARD15 | Canis lupus familiaris | 9615 | length:862
ARRLLDLATVKANGLAAFLLRHVQELPVPLAMPSEDAACKKYMSKLRTTISSQSRFLSTY
DGAENLCLEEIYTENVLEIRTEMGLARSPQKSPATLSLEELFSTCGHLNEDADTVLVVGE
AGSGKSTLLQRMHLLWASGRDFQEFLFVFPFSCRQLQCVAKPLSVQMLLFEHCCWPDFGQ
QEVFQFLLDHPNRVLLTFDGFDEFRFRFSDHERHCSPTDPTSVQNLLFNLLQGNLLKNAR
KVLTSRPDAVSALLRKYLRLEINLKGFSEEGIELYLRKCHREPGVADRLIRLLKTTSALH
GLCHLPVVSWMVSKCHQELLLHGGGSPKTSTDMYLLILQHFLLHASPPDSVPHSLGSHLL
RGRLPTLLHLGWLALWGLGMCCYVFSAKQLQAAHIDDEDISLGFLVHAKTVGPGSTTPLE
FLHITFQCFFAALYLVLSTDVSPSLLRQLFICHGPRSSLLARLLPTTCVPRSERKEGSLA
ALLQEAEPHNLQITAAFLAGLLSREHRGLLAECQANEEALLRLQGRAQGCLSRSLHQHFR
SIPPAVPGEAKSMHAMPGFLWLIRSLYEMQEERLAREAVRGLTVGHLKLTFCGVGPPECA
ALAFVLRHLRRPVALQLDHNSVGDIGVEQLLPCLSVCKALYLRDNNISDRGICKLIEHAL
HCEQLQKLALFNNKLTDGCAHSMARLLACKQNFLALRLGNNRITAAGAQALAEGLRANTS
LQFLGWKFPRVRGREWVALGCFVIAFHSINRKFRILVGNDIGSVGARALALMLEKNVALE
ELCLEENHLQDEGVCSLAKGLERNSSLKVLKLSNNCITYLGAEGLLQALEKNDTILEVWL
RGNTFSLEEMERLSQKDTRLLL
DGAENLCLEEIYTENVLEIRTEMGLARSPQKSPATLSLEELFSTCGHLNEDADTVLVVGE
AGSGKSTLLQRMHLLWASGRDFQEFLFVFPFSCRQLQCVAKPLSVQMLLFEHCCWPDFGQ
QEVFQFLLDHPNRVLLTFDGFDEFRFRFSDHERHCSPTDPTSVQNLLFNLLQGNLLKNAR
KVLTSRPDAVSALLRKYLRLEINLKGFSEEGIELYLRKCHREPGVADRLIRLLKTTSALH
GLCHLPVVSWMVSKCHQELLLHGGGSPKTSTDMYLLILQHFLLHASPPDSVPHSLGSHLL
RGRLPTLLHLGWLALWGLGMCCYVFSAKQLQAAHIDDEDISLGFLVHAKTVGPGSTTPLE
FLHITFQCFFAALYLVLSTDVSPSLLRQLFICHGPRSSLLARLLPTTCVPRSERKEGSLA
ALLQEAEPHNLQITAAFLAGLLSREHRGLLAECQANEEALLRLQGRAQGCLSRSLHQHFR
SIPPAVPGEAKSMHAMPGFLWLIRSLYEMQEERLAREAVRGLTVGHLKLTFCGVGPPECA
ALAFVLRHLRRPVALQLDHNSVGDIGVEQLLPCLSVCKALYLRDNNISDRGICKLIEHAL
HCEQLQKLALFNNKLTDGCAHSMARLLACKQNFLALRLGNNRITAAGAQALAEGLRANTS
LQFLGWKFPRVRGREWVALGCFVIAFHSINRKFRILVGNDIGSVGARALALMLEKNVALE
ELCLEENHLQDEGVCSLAKGLERNSSLKVLKLSNNCITYLGAEGLLQALEKNDTILEVWL
RGNTFSLEEMERLSQKDTRLLL
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0045449 | regulation of transcription | biological_proccess | IEA |
GO:0032760 | positive regulation of tumor necrosis factor production | biological_proccess | IEA |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB cascade | biological_proccess | IEA |
GO:0046330 | positive regulation of JNK cascade | biological_proccess | IEA |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | biological_proccess | IEA |
GO:0050718 | positive regulation of interleukin-1 beta secretion | biological_proccess | IEA |
GO:0032874 | positive regulation of stress-activated MAPK cascade | biological_proccess | IEA |
GO:0007242 | intracellular signaling cascade | biological_proccess | IEA |
GO:0016045 | detection of bacterium | biological_proccess | IEA |
GO:0032498 | detection of muramyl dipeptide | biological_proccess | IEA |
GO:0032740 | positive regulation of interleukin-17 production | biological_proccess | IEA |
GO:0002367 | cytokine production during immune response | biological_proccess | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0000166 | nucleotide binding | mollecular_function | IEA |
GO:0017111 | nucleoside-triphosphatase activity | mollecular_function | IEA |
GO:0005524 | ATP binding | mollecular_function | IEA |
GO:0030528 | transcription regulator activity | mollecular_function | IEA |
GO:0019901 | protein kinase binding | mollecular_function | IEA |
GO:0019899 | enzyme binding | mollecular_function | IEA |
GO:0032500 | muramyl dipeptide binding | mollecular_function | IEA |
GO:0050700 | CARD domain binding | mollecular_function | IEA |
GO:0009986 | cell surface | cell_component | IEA |
GO:0005829 | cytosol | cell_component | IEA |
GO:0005886 | plasma membrane | cell_component | IEA |
GO:0031982 | vesicle | cell_component | IEA |
GO:0008180 | signalosome | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSCAFG00000009818
- Expression info from Arrayexpress [?] : ENSCAFG00000009818
- Protein expression from Protein Atlas: [?] ENSCAFG00000009818
- entrezgene: 487286
Click on [?] for more information.