Your are not logged in. Log in.

CASP8   (Danio rerio)

Description [+]
  • Synonyms: CASP8, CASPASE 8, CASPASE-8, ZCASPASE-8A, MGC92075, ZGC:92075
  • Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Pisces; Danio rerio
  • Short gene description: caspase 8, apoptosis-related cysteine peptidase [Source:RefSeq_peptide;Acc:NP_571585]
  • Family: Caspase
  • Process: apoptosis,
  • Pathways: extrinsic pathway,
  • Criteria: manually curated
  • Curator comment: Ectopic expression of Casp8 in zebrafish embryos induces apoptosis [16888647]. Zebrafish Casp8 directly associates with FADD through homophilic death effector domain (DED) interactions [17459614]. Zebrafish Casp8 can mediate apoptosis following death receptor activation in mouse embryonic fibroblast cells that lack endogenous caspase-8 [17459614].
  • WIKI: CASP8-D_rerio
References [+]
Structure & Sequence [+]
Evolution [+]
Gene Ontology [+]
KEGG Pathways [+]
Information from other databases [+]