NP_001075265.1 (Equus caballus)
Description [+]
- Synonyms: NP_001075265.1
- Species: Equus caballus
- Short gene description: toll-like receptor 2 [Source:RefSeq_peptide;Acc:NP_001075265]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: NP_001075265.1-E_caballus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | TIR | 643 | 781 |
Protein sequence [+]
NP_001075265.1 | Equus caballus | 9796 | length:784
MPHALWTVWVLGAVISLSKEGVPDQPSSLSCDPTGVCDGRSRSLNSIPSGLTAAVKSLDL
SNNKIASVGNSDLWKCVNLKALRLGSNDINTIEEDSFSSLRSLEHLDLSNNHLSNLSSSW
FRPLSSLKFLNLLGSTYKTLGETSLFSHLTNLRILKVGNIHFTEIQGKDFAGLTFLEELE
IDATNLQRYEPKSFKSIQNISHLILRMKQPVLLPEIILDTLSSLEYLELRDTYLNTFHFA
EVSDPETNTLIKKFTFRNVKITDESFDEIVKLLNYISGVSEAEFDECTLDGLGEFRTPDI
DKIKVIGKLETLTIRRLRIPQFYLFRDLSSIYSLTERVKRITIENSKVFLVPCSLSRHLK
SLEYLDLSDNLMVEEYLKNSACERAWPSLQTLILRQNHLTSLGKTGETLLTLKNLTKLDI
SKNSFHSMPETCQWPEKMKYLNLSSIRIDRLTQCIPQTLEVLDISNNNLNSFSLILPQVK
ELYISRNKLKTLPDASFLPMLLVMRISRNTINTFSKEQLDSFQKLKTLEAGGNNFICSCE
FLSFTQEEQALDQILIDWPENYLCDSPSHVRGQRVQDTRLSVSECHRTALVSAVCCALFL
SILLTGVLCHHFHGLWYMKMMWAWLQAKRKPRTAPQRDICYDAFVSYSERDSYWVENLMV
QELEHFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTIFVLSENFVKSEWCKYELDFS
HFRLFDENNDAAILILLEPIDKKAIPQRFCKLRKIMNTKTYLEWPTDEAQQEGFWLNLRA
AIKS
SNNKIASVGNSDLWKCVNLKALRLGSNDINTIEEDSFSSLRSLEHLDLSNNHLSNLSSSW
FRPLSSLKFLNLLGSTYKTLGETSLFSHLTNLRILKVGNIHFTEIQGKDFAGLTFLEELE
IDATNLQRYEPKSFKSIQNISHLILRMKQPVLLPEIILDTLSSLEYLELRDTYLNTFHFA
EVSDPETNTLIKKFTFRNVKITDESFDEIVKLLNYISGVSEAEFDECTLDGLGEFRTPDI
DKIKVIGKLETLTIRRLRIPQFYLFRDLSSIYSLTERVKRITIENSKVFLVPCSLSRHLK
SLEYLDLSDNLMVEEYLKNSACERAWPSLQTLILRQNHLTSLGKTGETLLTLKNLTKLDI
SKNSFHSMPETCQWPEKMKYLNLSSIRIDRLTQCIPQTLEVLDISNNNLNSFSLILPQVK
ELYISRNKLKTLPDASFLPMLLVMRISRNTINTFSKEQLDSFQKLKTLEAGGNNFICSCE
FLSFTQEEQALDQILIDWPENYLCDSPSHVRGQRVQDTRLSVSECHRTALVSAVCCALFL
SILLTGVLCHHFHGLWYMKMMWAWLQAKRKPRTAPQRDICYDAFVSYSERDSYWVENLMV
QELEHFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKTIFVLSENFVKSEWCKYELDFS
HFRLFDENNDAAILILLEPIDKKAIPQRFCKLRKIMNTKTYLEWPTDEAQQEGFWLNLRA
AIKS
Structure links:
- Smartdomain prediction information: SM00365
- Smartdomain prediction information: SM00369
- Smartdomain prediction information: SM00364
- Smartdomain prediction information: SM00082
- Smartdomain prediction information: SM00255
- Prosite motif and domain information: PS00687
- Interpro domain information: Q6T752
- PFAM domain and domain family information: Q6T752
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0002238 | response to molecule of fungal origin | biological_proccess | IEA |
GO:0002752 | cell surface pattern recognition receptor signaling pathway | biological_proccess | IEA |
GO:0002755 | MyD88-dependent toll-like receptor signaling pathway | biological_proccess | IEA |
GO:0006954 | inflammatory response | biological_proccess | IEA |
GO:0006955 | immune response | biological_proccess | IEA |
GO:0007165 | signal transduction | biological_proccess | IEA |
GO:0032760 | positive regulation of tumor necrosis factor production | biological_proccess | IEA |
GO:0042892 | chloramphenicol transport | biological_proccess | IEA |
GO:0045087 | innate immune response | biological_proccess | IEA |
GO:0032755 | positive regulation of interleukin-6 production | biological_proccess | IEA |
GO:0004872 | receptor activity | mollecular_function | IEA |
GO:0004888 | transmembrane receptor activity | mollecular_function | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0042834 | peptidoglycan binding | mollecular_function | IEA |
GO:0051076 | Gram-positive bacterial binding | mollecular_function | IEA |
GO:0005886 | plasma membrane | cell_component | IEA |
GO:0009897 | external side of plasma membrane | cell_component | IEA |
GO:0016020 | membrane | cell_component | IEA |
GO:0016021 | integral to membrane | cell_component | IEA |
GO:0031224 | intrinsic to membrane | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSECAG00000018028
- Expression info from Arrayexpress [?] : ENSECAG00000018028
- Protein expression from Protein Atlas: [?] ENSECAG00000018028
- Community gene edition from Wikigenes: [?] 100009701
- entrezgene: 100009701
- refseq_peptide: NP_001075265
Click on [?] for more information.