TRAF5 (Homo sapiens)
Description [+]
- Synonyms: TRAF5
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Hominidae; Homo sapiens
- Short gene description: TNF receptor-associated factor 5 (RING finger protein 84) [Source:UniProtKB/Swiss-Prot;Acc:O00463]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: TRAF5-H_sapiens
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | zf-TRAF | 128 | 183 |
PFAM A | zf-TRAF | 184 | 241 |
PFAM A | MATH | 410 | 551 |
Protein sequence [+]
TRAF5 | Homo sapiens | 9606 | length:557
MAYSEEHKGMPCGFIRQNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGC
GHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKV
ILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINL
QNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQ
HEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFG
KNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLE
NNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREA
VDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQ
RVTLMLLDQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKD
DTLFLKVAVDLTDLEDL
GHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKV
ILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINL
QNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQ
HEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFG
KNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLE
NNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREA
VDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQ
RVTLMLLDQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKD
DTLFLKVAVDLTDLEDL
Structure links:
- Smartdomain prediction information: SM00184
- Smartdomain prediction information: SM00061
- Prosite motif and domain information: PS00518
- Profile motif and domain profile information: PS50144
- Profile motif and domain profile information: PS50089
- Profile motif and domain profile information: PS50145
- Interpro domain information: O00463
- PFAM domain and domain family information: O00463
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0008284 | positive regulation of cell proliferation | biological_proccess | IEA |
GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
GO:0007165 | signal transduction | biological_proccess | TAS |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB cascade | biological_proccess | IEP |
GO:0007165 | signal transduction | biological_proccess | IEA |
GO:0004871 | signal transducer activity | mollecular_function | IEA |
GO:0005515 | protein binding | mollecular_function | IPI |
GO:0008270 | zinc ion binding | mollecular_function | IEA |
GO:0046872 | metal ion binding | mollecular_function | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0005737 | cytoplasm | cell_component | IEA |
GO:0005813 | centrosome | cell_component | IDA |
Check GO Evidence Codes here
KEGG Pathways [+]
Information from other databases [+]
- Gene info from HGNC [?] :12035
- Gene related info from GeneCards [?] : TRAF5
- Ensembl genome browser [?] : ENSG00000082512
- Expression info from Arrayexpress [?] : ENSG00000082512
- Protein expression from Protein Atlas: [?] ENSG00000082512
- Community gene edition from Wikigenes: [?] 7188
- OMIM gene information: 602356
- OMIM disease information:
- entrezgene: 7188
- refseq_dna: NM_001033910
- refseq_dna: NM_145759
- refseq_dna: NM_004619
- refseq_peptide: NP_665702
- refseq_peptide: NP_001029082
- refseq_peptide: NP_004610
Click on [?] for more information.