TRAF3 (Homo sapiens)
Description [+]
- Synonyms: TRAF3
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Hominidae; Homo sapiens
- Short gene description: TNF receptor-associated factor 3 (CD40 receptor-associated factor 1)(CRAF1)(CD40-binding protein)(CD40BP)(LMP1-associated protein)(LAP1)(CAP-1) [Source:UniProtKB/Swiss-Prot;Acc:Q13114]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: TRAF3-H_sapiens
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | zf-TRAF | 136 | 192 |
PFAM A | zf-TRAF | 193 | 251 |
PFAM A | MATH | 422 | 562 |
Protein sequence [+]
TRAF3 | Homo sapiens | 9606 | length:568
MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL
CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE
SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC
KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV
FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG
EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ
TVLENGTYIKDDTIFIKVIVDTSDLPDP
CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE
SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC
KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV
FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG
EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ
TVLENGTYIKDDTIFIKVIVDTSDLPDP
Structure links:
- Smartdomain prediction information: SM00184
- Smartdomain prediction information: SM00061
- Prosite motif and domain information: PS00518
- Profile motif and domain profile information: PS50144
- Profile motif and domain profile information: PS50089
- Profile motif and domain profile information: PS50145
- Interpro domain information: Q13114
- PFAM domain and domain family information: Q13114
- Protein 3D structures from PDB: 2GKW 1FLK 1ZMS 2ECY 1FLL 1RF3 1KZZ 1L0A
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
GO:0006917 | induction of apoptosis | biological_proccess | TAS |
GO:0007165 | signal transduction | biological_proccess | TAS |
GO:0006011 | UDP-glucose metabolic process | biological_proccess | IEA |
GO:0007165 | signal transduction | biological_proccess | IEA |
GO:0005515 | protein binding | mollecular_function | IPI |
GO:0008270 | zinc ion binding | mollecular_function | IEA |
GO:0004871 | signal transducer activity | mollecular_function | TAS |
GO:0046872 | metal ion binding | mollecular_function | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0005737 | cytoplasm | cell_component | IEA |
GO:0016020 | membrane | cell_component | IEA |
Check GO Evidence Codes here
KEGG Pathways [+]
Information from other databases [+]
- Gene info from HGNC [?] :12033
- Gene related info from GeneCards [?] : TRAF3
- Ensembl genome browser [?] : ENSG00000131323
- Expression info from Arrayexpress [?] : ENSG00000131323
- Protein expression from Protein Atlas: [?] ENSG00000131323
- Community gene edition from Wikigenes: [?] 7187
- OMIM gene information: 601896
- OMIM disease information:
Click on [?] for more information.