MATK (Mus musculus)
Description [+]
- Synonyms: MATK
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Rodentia; Mus musculus
- Short gene description: megakaryocyte-associated tyrosine kinase Gene [Source:MGI (curated);Acc:Matk-001]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: MATK-M_musculus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
| Source | Domain Name | Start | End |
|---|---|---|---|
| PFAM A | SH2 | 121 | 195 |
| PFAM A | Pkinase | 234 | 477 |
| PFAM A | Pkinase_Tyr | 234 | 477 |
Protein sequence [+]
Matk | Mus musculus | 10090 | length:506
MARRSSRVSWLAFEGWESRDLPRVSPRLFGAWHPAPAAARMPTQRWAPGTQCMTKCENSR
PKPGELAFRKGDMVTILEACEDKSWYRAKHHGSGQEGLLAAAALRQREALSTDPKLSLMP
WFHGKISGQEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTID
EAVCFCNLMDMVEHYTKDKGAICTKLVKPRRKQGAKSAEEELAKAGWLLDLQHLTLGAQI
GEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKLQHRNLVRLLGVILHHGLY
IVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVS
EDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYG
RAPYPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGRE
LRSVGVSAPAGGQEAEGSAPTRSQDP
PKPGELAFRKGDMVTILEACEDKSWYRAKHHGSGQEGLLAAAALRQREALSTDPKLSLMP
WFHGKISGQEAIQQLQPPEDGLFLVRESARHPGDYVLCVSFGRDVIHYRVLHRDGHLTID
EAVCFCNLMDMVEHYTKDKGAICTKLVKPRRKQGAKSAEEELAKAGWLLDLQHLTLGAQI
GEGEFGAVLQGEYLGQKVAVKNIKCDVTAQAFLDETAVMTKLQHRNLVRLLGVILHHGLY
IVMEHVSKGNLVNFLRTRGRALVSTSQLLQFALHVAEGMEYLESKKLVHRDLAARNILVS
EDLVAKVSDFGLAKAERKGLDSSRLPVKWTAPEALKNGRFSSKSDVWSFGVLLWEVFSYG
RAPYPKMSLKEVSEAVEKGYRMEPPDGCPGSVHTLMGSCWEAEPARRPPFRKIVEKLGRE
LRSVGVSAPAGGQEAEGSAPTRSQDP
Structure links:
- Smartdomain prediction information: SM00326
- Smartdomain prediction information: SM00252
- Smartdomain prediction information: SM00219
- Smartdomain prediction information: SM00220
- Prosite motif and domain information: PS00107
- Prosite motif and domain information: PS00109
- Interpro domain information: P41242
- PFAM domain and domain family information: P41242
Evolution [+]
Explore tree at phylomeDB: Click here.
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Gene Ontology [+]
| GO id | Name | Ontology type | Evidence |
|---|---|---|---|
| GO:0006468 | protein amino acid phosphorylation | biological_proccess | IEA |
| GO:0007165 | signal transduction | biological_proccess | IEA |
| GO:0004672 | protein kinase activity | mollecular_function | IEA |
| GO:0005524 | ATP binding | mollecular_function | IEA |
| GO:0005515 | protein binding | mollecular_function | IEA |
| GO:0004713 | protein tyrosine kinase activity | mollecular_function | IEA |
| GO:0004674 | protein serine/threonine kinase activity | mollecular_function | IEA |
| GO:0000166 | nucleotide binding | mollecular_function | IEA |
| GO:0004715 | non-membrane spanning protein tyrosine kinase activity | mollecular_function | IEA |
| GO:0016740 | transferase activity | mollecular_function | IEA |
| GO:0016301 | kinase activity | mollecular_function | IEA |
| GO:0005737 | cytoplasm | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Gene info from MGI [?] MGI:99259
- Ensembl genome browser [?] : ENSMUSG00000004933
- Expression info from Arrayexpress [?] : ENSMUSG00000004933
- Protein expression from Protein Atlas: [?] ENSMUSG00000004933
- Community gene edition from Wikigenes: [?] 17179
Click on [?] for more information.
