PRDX2 (Mus musculus)

Description [+]

Synonyms: PRDX2
Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Rodentia; Mus musculus
Short gene description: peroxiredoxin 2 Gene [Source:MGI (curated);Acc:Prdx2-003]
Family: Null
Process:
Pathways:
Criteria: homology search
Curator comment: Null
WIKI: PRDX2-M_musculus

Structure & Sequence [+]

Source	Domain Name	Start	End
PFAM A	Redoxin	7	162
PFAM A	AhpC-TSA	8	141
PFAM A	1-cysPrx_C	151	194

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0000187	activation of MAPK activity	biological_proccess	IMP
GO:0002536	respiratory burst during acute inflammatory response	biological_proccess	IMP
GO:0006916	anti-apoptosis	biological_proccess	IMP
GO:0006979	response to oxidative stress	biological_proccess	TAS
GO:0010310	regulation of hydrogen peroxide metabolic process	biological_proccess	IMP
GO:0010671	negative regulation of oxygen and reactive oxygen species metabolic process	biological_proccess	IMP
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	biological_proccess	IMP
GO:0032088	negative regulation of NF-kappaB transcription factor activity	biological_proccess	IMP
GO:0032496	response to lipopolysaccharide	biological_proccess	IMP
GO:0042098	T cell proliferation	biological_proccess	IMP
GO:0042744	hydrogen peroxide catabolic process	biological_proccess	IMP
GO:0045454	cell redox homeostasis	biological_proccess	IEA
GO:0045581	negative regulation of T cell differentiation	biological_proccess	IMP
GO:0048538	thymus development	biological_proccess	IMP
GO:0048872	homeostasis of number of cells	biological_proccess	IMP
GO:0055114	oxidation reduction	biological_proccess	IEA
GO:0006800	oxygen and reactive oxygen species metabolic process	biological_proccess	TAS
GO:0042743	hydrogen peroxide metabolic process	biological_proccess	IMP
GO:0042981	regulation of apoptosis	biological_proccess	IEA
GO:0008379	thioredoxin peroxidase activity	mollecular_function	TAS
GO:0008430	selenium binding	mollecular_function	TAS
GO:0016491	oxidoreductase activity	mollecular_function	IEA
GO:0016209	antioxidant activity	mollecular_function	IEA
GO:0004601	peroxidase activity	mollecular_function	TAS
GO:0051920	peroxiredoxin activity	mollecular_function	IEA
GO:0008379	thioredoxin peroxidase activity	mollecular_function	IEA
GO:0005737	cytoplasm	cell_component	IEA

Check GO Evidence Codes here

Information from other databases [+]

Gene related links:

Gene info from MGI [?] MGI:109486
Ensembl genome browser [?] : ENSMUSG00000005161
Expression info from Arrayexpress [?] : ENSMUSG00000005161
Protein expression from Protein Atlas: [?] ENSMUSG00000005161
Community gene edition from Wikigenes: [?] 21672

Protein related links:

Uniprot protein info: Q61171
PIR protein info: Q61171
Protein interactions from IntAct: Q61171

Other links

entrezgene: 21672
refseq_dna: NM_011563
refseq_peptide: NP_035693

Click on [?] for more information.