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APAF1 (Ornithorhynchus anatinus)

Description [+]

Synonyms: APAF1
Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Prototheria; Ornithorhynchus anatinus
Short gene description: Apoptotic protease-activating factor 1 (Apaf-1) [Source:UniProtKB/Swiss-Prot;Acc:O14727]
Family: Null
Process:
Pathways:
Criteria: homology search
Curator comment: Null
WIKI: APAF1-O_anatinus

Structure & Sequence [+]

Pfam domains: (Pfam is a large collection of protein families.)

Source	Domain Name	Start	End
PFAM A	CARD	8	92
PFAM A	NB-ARC	131	417
PFAM A	WD40	608	646
PFAM A	WD40	650	688
PFAM A	WD40	692	732
PFAM A	WD40	736	774
PFAM A	WD40	874	912
PFAM A	WD40	1080	1118
PFAM A	WD40	1122	1160

Protein sequence [+]

Structure links:

Smartdomain prediction information: SM00114
Smartdomain prediction information: SM00320
Prosite motif and domain information: PS00678

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0006952	defense response	biological_proccess	IEA
GO:0042981	regulation of apoptosis	biological_proccess	IEA
GO:0006915	apoptosis	biological_proccess	IEA
GO:0008635	activation of caspase activity by cytochrome c	biological_proccess	IEA
GO:0007275	multicellular organismal development	biological_proccess	IEA
GO:0007420	brain development	biological_proccess	IEA
GO:0006309	DNA fragmentation during apoptosis	biological_proccess	IEA
GO:0006919	activation of caspase activity	biological_proccess	IEA
GO:0001843	neural tube closure	biological_proccess	IEA
GO:0030900	forebrain development	biological_proccess	IEA
GO:0051402	neuron apoptosis	biological_proccess	IEA
GO:0005515	protein binding	mollecular_function	IEA
GO:0005524	ATP binding	mollecular_function	IEA
GO:0042802	identical protein binding	mollecular_function	IEA
GO:0016505	apoptotic protease activator activity	mollecular_function	IEA
GO:0005622	intracellular	cell_component	IEA
GO:0005634	nucleus	cell_component	IEA
GO:0005625	soluble fraction	cell_component	IEA

Check GO Evidence Codes here

Information from other databases [+]