PRDX3_PONPY (Pongo pygmaeus)

Description [+]

Synonyms: PRDX3_PONPY
Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Hominidae; Pongo pygmaeus
Short gene description: Thioredoxin-dependent peroxide reductase, mitochondrial precursor (EC 1.11.1.15) (Peroxiredoxin-3). [Source:UniProtKB/Swiss-Prot;Acc:Q5REY3]
Family: Null
Process:
Pathways:
Criteria: homology search
Curator comment: Null
WIKI: PRDX3_PONPY-P_pygmaeus

Structure & Sequence [+]

Source	Domain Name	Start	End
PFAM A	Redoxin	64	219
PFAM A	AhpC-TSA	65	198
PFAM A	1-cysPrx_C	208	251

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0032496	response to lipopolysaccharide	biological_proccess	IEA
GO:0006979	response to oxidative stress	biological_proccess	IEA
GO:0030099	myeloid cell differentiation	biological_proccess	IEA
GO:0001893	maternal placenta development	biological_proccess	IEA
GO:0042542	response to hydrogen peroxide	biological_proccess	IEA
GO:0008284	positive regulation of cell proliferation	biological_proccess	IEA
GO:0051092	positive regulation of NF-kappaB transcription factor activity	biological_proccess	IEA
GO:0007005	mitochondrion organization	biological_proccess	IEA
GO:0043066	negative regulation of apoptosis	biological_proccess	IEA
GO:0051881	regulation of mitochondrial membrane potential	biological_proccess	IEA
GO:0034614	cellular response to reactive oxygen species	biological_proccess	IEA
GO:0042744	hydrogen peroxide catabolic process	biological_proccess	IEA
GO:0033673	negative regulation of kinase activity	biological_proccess	IEA
GO:0004601	peroxidase activity	mollecular_function	IEA
GO:0016209	antioxidant activity	mollecular_function	IEA
GO:0016491	oxidoreductase activity	mollecular_function	IEA
GO:0051920	peroxiredoxin activity	mollecular_function	IEA
GO:0042802	identical protein binding	mollecular_function	IEA
GO:0019901	protein kinase binding	mollecular_function	IEA
GO:0008022	protein C-terminus binding	mollecular_function	IEA
GO:0043027	caspase inhibitor activity	mollecular_function	IEA
GO:0005739	mitochondrion	cell_component	IEA
GO:0005737	cytoplasm	cell_component	IEA
GO:0005769	early endosome	cell_component	IEA
GO:0008385	IkappaB kinase complex	cell_component	IEA

Check GO Evidence Codes here

Information from other databases [+]