NLRP1 (Pongo pygmaeus)
Description [+]
- Synonyms: NLRP1
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Hominidae; Pongo pygmaeus
- Short gene description: NACHT, LRR and PYD domains-containing protein 1 (Death effector filament-forming ced-4-like apoptosis protein)(Nucleotide-binding domain and caspase recruitment domain)(Caspase recruitment domain-containing protein 7) [Source:UniProtKB/Swiss-Prot;Acc:Q9C000]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: NLRP1-P_pygmaeus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
| Source | Domain Name | Start | End |
|---|---|---|---|
| PFAM A | PAAD_DAPIN | 5 | 88 |
| PFAM A | NACHT | 328 | 497 |
| PFAM A | CARD | 1383 | 1466 |
Protein sequence [+]
NLRP1 | Pongo pygmaeus | 9600 | length:1477
MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQ
YGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPW
IHELPAGCTQGSERRVLRQLPDTSGRRWREISSSLLYQALPSSPDYESPSQESPNAPTST
AVLGSWGSPPQPSLAPREQEAPGTQWPLDEMSGIYYAEIREREREKSEKGRPPWAAAVGT
PPQAHTSLQPHRHPWEPSVRESLCSTWPWKNEDLNQKFTQLLLLQRPHPRSQVPLFKGSW
PHYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGER
FQHVFYFSCRELAQSKVVSLAELIGKDWTVTQAPIRQILSMPERLLFILDGVDEPGWVLQ
EPSSELCLHWSQPQQADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLG
FSESSRKEYFYKYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACACLMQQMKRKEKL
TLTSKTTTTLCLHYLSQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAV
ISTLLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYALENKKGKGKHSNCIIDLEKLLEAY
GTHGLFGASTTRFLLGLLSDEGEREMENIFHCQLSQGRNLMRWVPSLQLLLQPHSLESLH
CLYETRNKTFLTRVMAHFEEMGMCVETDMELLVSTFCIKFSRHVKKLQLIEGRQHRSTWS
PTMVVLFRWAPVTDAYWQILFSVLKVTRNLKELDLSGNSLSRSAVKSLCKTLRCPRCLLE
TLRLAGCGLIAEDCKDLASGLRANWTLTKLDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQ
LVSCGVTSDCCQDLASVLSASPILKELDLQQNNLDDAGVRLLCEGLRHPACKLIRLGLDQ
TTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPIEGLDTGETSNSTSSLKRQRLRSETE
PSHIAQADLKRLDWSNPPAKASQSAGITEGSSPEVAQVEPLCLPSPASQGDLHTKALGTD
DDFWGPTGPVAAEIVDKEKSLYRVHFPVAGSYRWPNMGLCFVVREAVTVEIEFCVWDQFL
GEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQVAHFKEEGMLLEK
PARVELHHIVLENPSFSPLGVLLKMIHNALRFLPVTSVVLLYHRLHPEEVTFHLYLIPSD
CSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGE
DQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATALVPPACIAVPSPLDAP
RLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAEDTRPSQMRKLFSLSQSW
DRRCKDRLYQALKETHPHLIMELWEKGSKKGLLPLSS
YGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPW
IHELPAGCTQGSERRVLRQLPDTSGRRWREISSSLLYQALPSSPDYESPSQESPNAPTST
AVLGSWGSPPQPSLAPREQEAPGTQWPLDEMSGIYYAEIREREREKSEKGRPPWAAAVGT
PPQAHTSLQPHRHPWEPSVRESLCSTWPWKNEDLNQKFTQLLLLQRPHPRSQVPLFKGSW
PHYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGER
FQHVFYFSCRELAQSKVVSLAELIGKDWTVTQAPIRQILSMPERLLFILDGVDEPGWVLQ
EPSSELCLHWSQPQQADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLG
FSESSRKEYFYKYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACACLMQQMKRKEKL
TLTSKTTTTLCLHYLSQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAV
ISTLLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYALENKKGKGKHSNCIIDLEKLLEAY
GTHGLFGASTTRFLLGLLSDEGEREMENIFHCQLSQGRNLMRWVPSLQLLLQPHSLESLH
CLYETRNKTFLTRVMAHFEEMGMCVETDMELLVSTFCIKFSRHVKKLQLIEGRQHRSTWS
PTMVVLFRWAPVTDAYWQILFSVLKVTRNLKELDLSGNSLSRSAVKSLCKTLRCPRCLLE
TLRLAGCGLIAEDCKDLASGLRANWTLTKLDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQ
LVSCGVTSDCCQDLASVLSASPILKELDLQQNNLDDAGVRLLCEGLRHPACKLIRLGLDQ
TTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPIEGLDTGETSNSTSSLKRQRLRSETE
PSHIAQADLKRLDWSNPPAKASQSAGITEGSSPEVAQVEPLCLPSPASQGDLHTKALGTD
DDFWGPTGPVAAEIVDKEKSLYRVHFPVAGSYRWPNMGLCFVVREAVTVEIEFCVWDQFL
GEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQVAHFKEEGMLLEK
PARVELHHIVLENPSFSPLGVLLKMIHNALRFLPVTSVVLLYHRLHPEEVTFHLYLIPSD
CSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGE
DQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATALVPPACIAVPSPLDAP
RLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAEDTRPSQMRKLFSLSQSW
DRRCKDRLYQALKETHPHLIMELWEKGSKKGLLPLSS
Structure links:
Evolution [+]
Explore tree at phylomeDB: Click here.
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Gene Ontology [+]
| GO id | Name | Ontology type | Evidence |
|---|---|---|---|
| GO:0006952 | defense response | biological_proccess | IEA |
| GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
| GO:0051402 | neuron apoptosis | biological_proccess | IEA |
| GO:0005515 | protein binding | mollecular_function | IEA |
| GO:0000166 | nucleotide binding | mollecular_function | IEA |
| GO:0017111 | nucleoside-triphosphatase activity | mollecular_function | IEA |
| GO:0005524 | ATP binding | mollecular_function | IEA |
| GO:0019899 | enzyme binding | mollecular_function | IEA |
| GO:0019904 | protein domain specific binding | mollecular_function | IEA |
| GO:0005622 | intracellular | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSPPYG00000007874
- Expression info from Arrayexpress [?] : ENSPPYG00000007874
- Protein expression from Protein Atlas: [?] ENSPPYG00000007874
Click on [?] for more information.
