ZAP70 (Pan troglodytes)

Description [+]

Synonyms: ZAP70
Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Hominidae; Pan troglodytes
Short gene description: Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2)(70 kDa zeta-associated protein)(Syk-related tyrosine kinase) [Source:UniProtKB/Swiss-Prot;Acc:P43403]
Family: Null
Process:
Pathways:
Criteria: homology search
Curator comment: Null
WIKI: ZAP70-P_troglodytes

Structure & Sequence [+]

Pfam domains: (Pfam is a large collection of protein families.)

Source	Domain Name	Start	End
PFAM A	SH2	10	87
PFAM A	SH2	163	239
PFAM A	Pkinase	338	593
PFAM A	Pkinase_Tyr	338	593

Protein sequence [+]

Structure links:

Smartdomain prediction information: SM00252
Smartdomain prediction information: SM00219
Smartdomain prediction information: SM00220
Prosite motif and domain information: PS00107
Prosite motif and domain information: PS00109

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0006468	protein amino acid phosphorylation	biological_proccess	IEA
GO:0007165	signal transduction	biological_proccess	IEA
GO:0006955	immune response	biological_proccess	IEA
GO:0045582	positive regulation of T cell differentiation	biological_proccess	IEA
GO:0045059	positive thymic T cell selection	biological_proccess	IEA
GO:0007242	intracellular signaling cascade	biological_proccess	IEA
GO:0046777	protein amino acid autophosphorylation	biological_proccess	IEA
GO:0050852	T cell receptor signaling pathway	biological_proccess	IEA
GO:0046641	positive regulation of alpha-beta T cell proliferation	biological_proccess	IEA
GO:0018108	peptidyl-tyrosine phosphorylation	biological_proccess	IEA
GO:0050850	positive regulation of calcium-mediated signaling	biological_proccess	IEA
GO:0046638	positive regulation of alpha-beta T cell differentiation	biological_proccess	IEA
GO:0045060	negative thymic T cell selection	biological_proccess	IEA
GO:0045061	thymic T cell selection	biological_proccess	IEA
GO:0043366	beta selection	biological_proccess	IEA
GO:0004672	protein kinase activity	mollecular_function	IEA
GO:0005524	ATP binding	mollecular_function	IEA
GO:0005515	protein binding	mollecular_function	IEA
GO:0004713	protein tyrosine kinase activity	mollecular_function	IEA
GO:0004674	protein serine/threonine kinase activity	mollecular_function	IEA
GO:0004715	non-membrane spanning protein tyrosine kinase activity	mollecular_function	IEA
GO:0001784	phosphotyrosine binding	mollecular_function	IEA
GO:0005737	cytoplasm	cell_component	IEA
GO:0042101	T cell receptor complex	cell_component	IEA
GO:0005829	cytosol	cell_component	IEA

Check GO Evidence Codes here

Information from other databases [+]