PRDX2 (Rattus norvegicus)
Description [+]
- Synonyms: PRDX2
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Rodentia; Rattus norvegicus
- Short gene description: Peroxiredoxin-2 (EC 1.11.1.15) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thiol-specific antioxidant protein) (TSA). [Source:UniProtKB/Swiss-Prot;Acc:P35704]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: PRDX2-R_norvegicus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
| Source | Domain Name | Start | End |
|---|---|---|---|
| PFAM A | Redoxin | 7 | 162 |
| PFAM A | AhpC-TSA | 8 | 141 |
| PFAM A | 1-cysPrx_C | 151 | 194 |
Protein sequence [+]
Prdx2 | Rattus norvegicus | 10116 | length:198
MASGNAHIGKPAPDFTATAVVDGAFKEIKLSDYRGKYVVLFFYPLDFTFVCPTEIIAFSD
HAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTKSLSQNYGVLKN
DEGIAYRGLFIIDAKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGS
DTIKPNVDDSKEYFSKHN
HAEDFRKLGCEVLGVSVDSQFTHLAWINTPRKEGGLGPLNIPLLADVTKSLSQNYGVLKN
DEGIAYRGLFIIDAKGVLRQITVNDLPVGRSVDEALRLVQAFQYTDEHGEVCPAGWKPGS
DTIKPNVDDSKEYFSKHN
Evolution [+]
Explore tree at phylomeDB: Click here.
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Gene Ontology [+]
| GO id | Name | Ontology type | Evidence |
|---|---|---|---|
| GO:0006979 | response to oxidative stress | biological_proccess | IMP |
| GO:0043524 | negative regulation of neuron apoptosis | biological_proccess | IMP |
| GO:0045454 | cell redox homeostasis | biological_proccess | IEA |
| GO:0055114 | oxidation reduction | biological_proccess | IEA |
| GO:0016491 | oxidoreductase activity | mollecular_function | IEA |
| GO:0051920 | peroxiredoxin activity | mollecular_function | IEA |
| GO:0016209 | antioxidant activity | mollecular_function | IEA |
| GO:0005737 | cytoplasm | cell_component | IEA |
| GO:0005829 | cytosol | cell_component | IDA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSRNOG00000003520
- Expression info from Arrayexpress [?] : ENSRNOG00000003520
- Protein expression from Protein Atlas: [?] ENSRNOG00000003520
Click on [?] for more information.
