NOTC1_RAT (Rattus norvegicus)

Description [+]

Synonyms: NOTC1_RAT
Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Rodentia; Rattus norvegicus
Short gene description: Neurogenic locus notch homolog protein 1 Precursor (Notch 1) [Contains Notch 1 extracellular truncation;Notch 1 intracellular domain] [Source:UniProtKB/Swiss-Prot;Acc:Q07008]
Family: Null
Process:
Pathways:
Criteria: homology search
Curator comment: Null
WIKI: NOTC1_RAT-R_norvegicus

Structure & Sequence [+]

Protein sequence [+]

NOTC1_RAT | Rattus norvegicus | 10116 | length:2511

GLRCSQPSGTCLNGGRCEVANGTEACVCSGAFVGQRCQDPSPCLSTPCKNAGTCYVVDHG
GIVDYACSCPLGFSGPLCLTPLANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ
ADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEIG
SYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVDD
CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNSHGGYN
CVCVNGWTGEDCSENIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACISNP
CNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQC
LQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCL
HNGRCVDKINEFLCQCPKGFSGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTG
THCEVDIDECDPDPCHYGLCKDGVATFTCLCQPGYTGHHCETNINECHSQPCRHGGTCQD
RDNYYLCLCLKGTTGPNCEINLDDCASNPCDSGTCLDKIDGYECACEPGYTGSMCNVNID
ECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIHGACRDGLNGYKCD
CAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPC
LNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTG
WQGQTCEIDINECVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGG
SCTDGVNAAFCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVDSYTCTCPTGFNGIHC
ENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCLHGGTCQDSY
GTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGKCWQTNTQYHCECRSGWTGFNCDVLSVS
CEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEVDECSPNPCQNGATC
TDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCEI
NVDDCHPPLDPASRSPKCFNNGTCVDQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRG
TQNCVQRVNDFHCECRAGHTGRRCESVINGCRGKPCRNGGVCAVASNTARGFICRCPAGF
EGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGSFTGPECQFPASSPCVGSNPCYNQ
GTCEPTSESPFYRCLCPAKFNGLLCHILDYSFTGGAGRDIPPPQIEEACELPECQEDAGN
KVCNLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCLFDGFD
CQLTEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVPERLAAGTLVLVVLL
PPDQLRNNSFHFLRELSHVLHTNVVFKRDAQGQQMIFPYYGREEELRKHPIKRSAVGWAT
TSLLPGTNGGRQRRELDPMDIHGSIVYLEIDNRQCVQSSSQCFQSATDVAAFLGALASLG
SLNIPYKIEAVKSETVEPPLPSQLHLMYVAAAAFVLLFFVGCGVLLSRKRRRQHGQLWFP
EGFKVSEASKKKRREPLGEDSVGLKPLKNASDGALMDDNQNEWGDEDLETKKFRFEEPVV
LPDLDDQTDHRQWTQQHLDAADLRVSAMAPTPPQGEVDADCMDVNVRGPDGFTPLMIASC
SGGGLETGNSEEEEDAPAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEA
SADANIQDNMGRTPLHAAVSADAQGVFQILLRNRATDLDARMHDGTTPLILAARLAVEGM
LEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGANKDMQNNKEETPLFLAAR
EGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRLLDEYNLVRSPQLHGTALG
GTPTLSPTLCSPNGYLGNLKSATQGKKARKPSTKGLACSSKEAKDLKARRKKSQDGKGCL
LDSSSMLSPVDSLESPHGYLSDVASPPLLPSPFQQSPSMPLSHLPGMPDTHLGISHLNVA
AKPEMAALAGGSRLAFEPPPPRLSHLPVASSASTVLSTNGTGAMNFTVGAPASLNGQCEW
LPRLQNGMVPSQYNPLRPGVTPGTLSTQAAGLQHGMMGPIHSSLSTNTLSPIIYQGLPNT
RLATQPHLVQTQQVQPQNLQIQPQNLQPPSQPHLSVSSAANGHLGRSFLSGEPSQADVQP
LGPSSLPVHTILPQESQALPTSLPSSMVPPMTTTQFLTPPSQHSYSSSPVDNTPSHQLQV
PEHPFLTPSPESPDQWSSSSPHSNISDWSEGISSPPTSMPSQITHIPEAFK

BLAST at NCBI | WU-BLAST2 at EBI

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0006350	transcription	biological_proccess	IEA
GO:0006355	regulation of transcription, DNA-dependent	biological_proccess	IEA
GO:0007221	positive regulation of transcription of Notch receptor target	biological_proccess	IMP
GO:0007283	spermatogenesis	biological_proccess	IMP
GO:0009790	embryonic development	biological_proccess	IDA
GO:0030154	cell differentiation	biological_proccess	IEA
GO:0042246	tissue regeneration	biological_proccess	IEP
GO:0045687	positive regulation of glial cell differentiation	biological_proccess	IMP
GO:0048709	oligodendrocyte differentiation	biological_proccess	IEP
GO:0050793	regulation of developmental process	biological_proccess	IEA
GO:0007219	Notch signaling pathway	biological_proccess	IEA
GO:0007275	multicellular organismal development	biological_proccess	IEA
GO:0001889	liver development	biological_proccess	IEA
GO:0010468	regulation of gene expression	biological_proccess	IEA
GO:0007368	determination of left/right symmetry	biological_proccess	IEA
GO:0007507	heart development	biological_proccess	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	biological_proccess	IEA
GO:0007409	axonogenesis	biological_proccess	IEA
GO:0030324	lung development	biological_proccess	IEA
GO:0048663	neuron fate commitment	biological_proccess	IEA
GO:0035116	embryonic hindlimb morphogenesis	biological_proccess	IEA
GO:0008284	positive regulation of cell proliferation	biological_proccess	IEA
GO:0006357	regulation of transcription from RNA polymerase II promoter	biological_proccess	IEA
GO:0007386	compartment specification	biological_proccess	IEA
GO:0043066	negative regulation of apoptosis	biological_proccess	IEA
GO:0031069	hair follicle morphogenesis	biological_proccess	IEA
GO:0030182	neuron differentiation	biological_proccess	IEA
GO:0030326	embryonic limb morphogenesis	biological_proccess	IEA
GO:0048754	branching morphogenesis of a tube	biological_proccess	IEA
GO:0045665	negative regulation of neuron differentiation	biological_proccess	IEA
GO:0030900	forebrain development	biological_proccess	IEA
GO:0008544	epidermis development	biological_proccess	IEA
GO:0001837	epithelial to mesenchymal transition	biological_proccess	IEA
GO:0043065	positive regulation of apoptosis	biological_proccess	IEA
GO:0042640	anagen	biological_proccess	IEA
GO:0045165	cell fate commitment	biological_proccess	IEA
GO:0007492	endoderm development	biological_proccess	IEA
GO:0030216	keratinocyte differentiation	biological_proccess	IEA
GO:0002040	sprouting angiogenesis	biological_proccess	IEA
GO:0010001	glial cell differentiation	biological_proccess	IEA
GO:0045596	negative regulation of cell differentiation	biological_proccess	IEA
GO:0050767	regulation of neurogenesis	biological_proccess	IEA
GO:0001708	cell fate specification	biological_proccess	IEA
GO:0007440	foregut morphogenesis	biological_proccess	IEA
GO:0045618	positive regulation of keratinocyte differentiation	biological_proccess	IEA
GO:0046533	negative regulation of photoreceptor cell differentiation	biological_proccess	IEA
GO:0048103	somatic stem cell division	biological_proccess	IEA
GO:0050678	regulation of epithelial cell proliferation	biological_proccess	IEA
GO:0045662	negative regulation of myoblast differentiation	biological_proccess	IEA
GO:0003700	transcription factor activity	mollecular_function	IMP
GO:0004872	receptor activity	mollecular_function	IEA
GO:0005509	calcium ion binding	mollecular_function	IEA
GO:0016563	transcription activator activity	mollecular_function	IMP
GO:0003700	transcription factor activity	mollecular_function	IEA
GO:0043565	sequence-specific DNA binding	mollecular_function	IEA
GO:0005515	protein binding	mollecular_function	IEA
GO:0003682	chromatin binding	mollecular_function	IEA
GO:0031490	chromatin DNA binding	mollecular_function	IEA
GO:0001669	acrosome	cell_component	IDA
GO:0005634	nucleus	cell_component	IEA
GO:0005794	Golgi apparatus	cell_component	IDA
GO:0005886	plasma membrane	cell_component	IEA
GO:0016021	integral to membrane	cell_component	IEA
GO:0016020	membrane	cell_component	IEA
GO:0005737	cytoplasm	cell_component	IEA

Check GO Evidence Codes here

Information from other databases [+]