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Full view of all proteins: here.
SymbolSynonymsDescriptionEvidenceEx.Link
AIFM1 AIFM1, APOPTOSIS-INDUCING FACTOR, MITOCHONDRION-ASSOCIATED 1, AIF, PDCD8 apoptosis-inducing factor, mitochondrion-associated 1 Gene [Source:MGI (curated);Acc:Aifm1-001] manually curated
ANXA1 ANX1, LPC-1, LPC1, ANNEXIN A1, LIPOCORTIN I Annexin A1 (Annexin-1)(Annexin I)(Lipocortin I)(Calpactin II)(Chromobindin-9)(p35)(Phospholipase A2 inhibitory protein) [Source:UniProtKB/Swiss-Prot;Acc:P10107] manually curated
APAF1 APAF1, APOPTOTIC PEPTIDASE ACTIVATING FACTOR 1 apoptotic peptidase activating factor 1 Gene [Source:MGI Symbol;Acc:MGI:1306796] manually curated
BAD BBC6, BCL2-ASSOCIATED AGONIST OF CELL DEATH BCL2-associated agonist of cell death Gene [Source:MGI (curated);Acc:Bad-001] manually curated
BAK1 BCL2-ANTAGONIST/KILLER 1, BAK, N-BAK BCL2-antagonist/killer 1 Gene [Source:MGI (curated);Acc:Bak1-001] manually curated
BAX BAX, BCL2-ASSOCIATED X PROTEIN BCL2-associated X protein Gene [Source:MGI Symbol;Acc:MGI:99702] manually curated
BBC3 BBC3, BCL2 BINDING COMPONENT 3, PUMA Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) [Source:UniProtKB/Swiss-Prot;Acc:Q99ML1] manually curated
BCL2 BCL2, B-CELL LEUKEMIA/LYMPHOMA 2 B-cell leukemia/lymphoma 2 Gene [Source:MGI (curated);Acc:Bcl2-001] manually curated
BCL2A1A BCL2A1A, B-CELL LEUKEMIA/LYMPHOMA 2 RELATED PROTEIN A1A, A1, BCL2A1, BFL-1, HBPA1 Bcl-2-related protein A1 (Protein BFL-1)(Hemopoietic-specific early response protein)(A1-A) [Source:UniProtKB/Swiss-Prot;Acc:Q07440] manually curated
BCL2L1 BCL2L1, BCL2-LIKE 1, BCL(X)L, BCL-X, BCL-XL, BCL-XS, BCLX BCL2-like 1 Gene [Source:MGI (curated);Acc:Bcl2l1-001] manually curated
BCL2L10 BCL2L10, BCL2-LIKE 10, BOO, DIVA Bcl2-like 10 Gene [Source:MGI Symbol;Acc:MGI:1330841] manually curated
BCL2L11 BCL2L11, BCL2-LIKE 11 (APOPTOSIS FACILITATOR), 1500006F24RIK, BIM, BOD BCL2-like 11 (apoptosis facilitator) Gene [Source:MGI (curated);Acc:Bcl2l11-001] manually curated
BCL2L2 BCL-W, BCLW, GTRGAL2, GTROSA41,BCL2L2, BCL2-LIKE 2 BCL2-like 2 Gene [Source:MGI Symbol;Acc:MGI:108052] manually curated
BID BID, BH3 INTERACTING DOMAIN DEATH AGONIST BH3 interacting domain death agonist Gene [Source:MGI (curated);Acc:Bid-001] manually curated
BIK BIK, BCL2-INTERACTING KILLER BCL2-interacting killer [Source:RefSeq peptide;Acc:NP_031572] manually curated Uniprot
BIRC5 API4, IAP4, SURVIVIN, TIAP, APOPTOSIS INHIBITOR 4 Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor survivin)(Apoptosis inhibitor 4)(TIAP) [Source:UniProtKB/Swiss-Prot;Acc:O70201] manually curated
BMF BMF, BCL2 MODIFYING FACTOR BCL2 modifying factor Gene [Source:MGI (curated);Acc:Bmf-001] manually curated
BNIP3 BNIP3, BCL2/ADENOVIRUS E1B INTERACTING PROTEIN 3 BCL2/adenovirus E1B interacting protein 3 Gene [Source:MGI (curated);Acc:Bnip3-001] manually curated
BNIP3L BNIP3L, BCL2/ADENOVIRUS E1B INTERACTING PROTEIN 3-LIKE BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (NIP3-like protein X)(NIP3L) [Source:UniProtKB/Swiss-Prot;Acc:Q9Z2F7] manually curated
BOK BOK, BCL2-RELATED OVARIAN KILLER PROTEIN BCL2-related ovarian killer protein Gene [Source:MGI Symbol;Acc:MGI:1858494] manually curated
CALR CALREGULIN,CRP55,HACBP,ERP60 Calreticulin Precursor (CRP55)(Calregulin)(HACBP)(ERp60) [Source:UniProtKB/Swiss-Prot;Acc:P14211] manually curated
CASP1 CASPASE 1, CASPASE-1, ICE, IL1BC, INTERLEUKIN 1 BETA-CONVERTING ENZYME caspase 1 Gene [Source:MGI Symbol;Acc:MGI:96544] manually curated
CASP12 CASP12, CASPASE 12 caspase 12 Gene [Source:MGI Symbol;Acc:MGI:1312922] manually curated
CASP2 CASPASE 2, CASPASE-2, ICH-1, NEDD2 caspase 2 Gene [Source:MGI (curated);Acc:Casp2-001] manually curated
CASP3 CASPASE 3, A830040C14RIK, APOPAIN, CASPASE-3, CC3, CPP32, YAMA caspase 3 Gene [Source:MGI Symbol;Acc:MGI:107739] manually curated
CASP4 CASPASE 4, CASP11, CASPASE-11, ICH-3 caspase 4, apoptosis-related cysteine peptidase Gene [Source:MGI Symbol;Acc:MGI:107700] manually curated
CASP6 CASPASE 6, MCASP-6, MCH2 caspase 6 Gene [Source:MGI (curated);Acc:Casp6-001] manually curated
CASP7 CASPASE 7, CASPASE-7, CMH-1, ICE-IAP3, MCH3 caspase 7 Gene [Source:MGI Symbol;Acc:MGI:109383] manually curated
CASP8 CASPASE 8, CASPASE-8, FLICE, MACH, MCH5 caspase 8 Gene [Source:MGI Symbol;Acc:MGI:1261423] manually curated
CASP9 CASPASE 9, CASPASE-9, ICE-LAP6, MCH6 caspase 9 [Source:RefSeq peptide;Acc:NP_056548] manually curated Uniprot
CASPASE-14 CASPASE 14, CASPASE-14, CASP14, MICE, MINI-ICE murine caspase 14 manually curated
CD36 Platelet glycoprotein 4 (Platelet glycoprotein IV)(GPIV)(GPIIIB)(PAS IV)(PAS-4)(CD36 antigen) [Source:UniProtKB/Swiss-Prot;Acc:Q08857] manually curated
CFLAR CASP8 AND FADD-LIKE APOPTOSIS REGULATOR, 2310024N18RIK, A430105C05RIK, C-FLIP, CASH, CASPER, FLIP CASP8 and FADD-like apoptosis regulator Precursor (Cellular FLICE-like inhibitory protein)(c-FLIP)(Caspase-eight-related protein)(Casper)(Caspase-like apoptosis regulatory protein)(CLARP)(MACH-related inducer of toxicity)(MRIT)(Caspase homolog)(CASH)(Inhibitor of FLICE)(I-FLICE)(FADD-like antiapoptotic molecule 1)(FLAME-1)(Usurpin) [Contains CASP8 and FADD-like apoptosis regulator subunit p43;CASP8 and FADD-like apoptosis regulator subunit p12] [Source:UniProtKB/Swiss-Prot;Acc:O35732] manually curated
CIAP1 BIRC2, API1, CIAP-1, CIAP1, HIAP1, IAP1, MCIAP1, MIAP1, MIHB, BIRC2, BACULOVIRAL IAP REPEAT-CONTAINING 2 baculoviral IAP repeat-containing 2 Gene manually curated
CIAP2 BIRC3, API2, CIAP-2, CIAP2, HIAP2, IAP2, MIAP2, MIHC, RNF49 baculoviral IAP repeat-containing 3 Gene manually curated
CYCS CYCS, CYTOCHROME C, SOMATIC Cytochrome c, somatic [Source:UniProtKB/Swiss-Prot;Acc:P62897] manually curated
CYLD CYLD, CYLINDROMATOSIS (TURBAN TUMOR SYNDROME) cylindromatosis (turban tumor syndrome) Gene [Source:MGI Symbol;Acc:MGI:1921506] manually curated
DIABLO DIABLO HOMOLOG (DROSOPHILA), 0610041G12RIK, 1700006L01RIK, SMAC Diablo homolog, mitochondrial Precursor (Second mitochondria-derived activator of caspase)(Smac protein)(Direct IAP-binding protein with low pI) [Source:UniProtKB/Swiss-Prot;Acc:Q9JIQ3] manually curated
DP5 HRK, HARAKIRI, BCL2 INTERACTING PROTEIN (CONTAINS ONLY BH3 DOMAIN) Activator of apoptosis harakiri (Neuronal death protein DP5)(BH3-interacting domain-containing protein 3) [Source:UniProtKB/Swiss-Prot;Acc:P62816] manually curated
FADD FADD, FAS (TNFRSF6)-ASSOCIATED VIA DEATH DOMAIN Protein FADD (FAS-associated death domain protein)(FAS-associating death domain-containing protein)(Mediator of receptor induced toxicity) [Source:UniProtKB/Swiss-Prot;Acc:Q61160] manually curated
FAS FAS, FAS (TNF RECEPTOR SUPERFAMILY MEMBER 6) Tumor necrosis factor receptor superfamily member 6 Precursor (FASLG receptor)(Apoptosis-mediating surface antigen FAS)(Apo-1 antigen)(CD95 antigen) [Source:UniProtKB/Swiss-Prot;Acc:P25446] manually curated
FASL FASL, FAS LIGAND (TNF SUPERFAMILY, MEMBER 6) Tumor necrosis factor ligand superfamily member 6 (Fas antigen ligand)(Fas ligand)(CD95L protein)(CD178 antigen) [Contains Tumor necrosis factor ligand superfamily member 6, membrane form;Tumor necrosis factor ligand superfamily member 6, soluble form] [Source:UniProtKB/Swiss-Prot;Acc:P41047] manually curated
GZMB GZMB, GRANZYME B,CTLA-1, CTLA1,GRB Granzyme B(G,H) Precursor (EC 3.4.21.79)(Cytotoxic cell protease 1)(CCP1)(CTLA-1)(Fragmentin-2) [Source:UniProtKB/Swiss-Prot;Acc:P04187] manually curated
LRDD PIDD, LRDD, LEUCINE-RICH AND DEATH DOMAIN CONTAINING, 1200011D09RIK Leucine-rich repeat and death domain-containing protein [Source:UniProtKB/Swiss-Prot;Acc:Q9ERV7] manually curated
MCL1 MCL1, MYELOID CELL LEUKEMIA SEQUENCE 1 Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Bcl-2-related protein EAT/mcl1) [Source:UniProtKB/Swiss-Prot;Acc:P97287] manually curated
NLRP1A NLRP1A, NLR FAMILY, PYRIN DOMAIN CONTAINING 1A NLR family, pyrin domain containing 1A [Source:RefSeq peptide;Acc:NP_001004142] manually curated Uniprot
NLRP3 NLRP3, NLR FAMILY, PYRIN DOMAIN CONTAINING 3 NACHT, LRR and PYD domains-containing protein 3 (Cold autoinflammatory syndrome 1 protein homolog)(Cryopyrin)(PYRIN-containing APAF1-like protein 1)(Mast cell maturation-associated-inducible protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q8R4B8] manually curated
PARP1 PARP1, POLY (ADP-RIBOSE) POLYMERASE FAMILY, MEMBER 1 Poly [ADP-ribose] polymerase 1 (PARP-1)(EC 2.4.2.30)(ADPRT)(NAD(+) ADP-ribosyltransferase 1)(Poly[ADP-ribose] synthetase 1)(msPARP) [Source:UniProtKB/Swiss-Prot;Acc:P11103] manually curated
PARP2 PARP2, POLY (ADP-RIBOSE) POLYMERASE FAMILY, MEMBER 2 poly (ADP-ribose) polymerase family, member 2 Gene [Source:MGI Symbol;Acc:MGI:1341112] manually curated
PMAIP1 NOXA, PHORBOL-12-MYRISTATE-13-ACETATE-INDUCED PROTEIN 1 Phorbol-12-myristate-13-acetate-induced protein 1 (Noxa) [Source:UniProtKB/Swiss-Prot;Acc:Q9JM54] manually curated
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 Gene [Source:MGI Symbol;Acc:MGI:108212] manually curated
RIPK3 RIPK3, RECEPTOR-INTERACTING SERINE-THREONINE KINASE 3 Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1)(RIP-like protein kinase 3)(Receptor-interacting protein 3)(RIP-3)(mRIP3) [Source:UniProtKB/Swiss-Prot;Acc:Q9QZL0] manually curated
TNF TNF, TUMOR NECROSIS FACTOR, DIF, TNF ALPHA, TNF-ALPHA, TNFA, TNFALPHA, TNFSF1A, TUMOR NECROSIS FACTOR-ALPHA Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)(TNF-a)(Cachectin) [Contains Tumor necrosis factor, membrane form;Tumor necrosis factor, soluble form] [Source:UniProtKB/Swiss-Prot;Acc:P06804] manually curated
TNFRSF10B TNFRSF10B, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B, DR5, KILLER, KILLER/DR5, LY98, TRAIL RECEPTOR, TRAIL-R2, TRAILR2, TRICK2A, TRICK2B, TRICKB Tumor necrosis factor receptor superfamily member 10B Precursor (Death receptor 5)(MK)(CD262 antigen) [Source:UniProtKB/Swiss-Prot;Acc:Q9QZM4] manually curated
TNFRSF1A TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A, CD120A, P55, P55-R, TNF RECEPTOR ALPHA CHAIN, TNF-ALPHA-R1, TNF-ALPHAR1, TNF-R-I, TNF-R1, TNF-R55, TNFALPHA-R1, TNFAR, TNFR-2, TNFR1, TNFR60, TNFRI, TNFRP55 Tumor necrosis factor receptor superfamily member 1A Precursor (p60)(TNF-R1)(TNF-RI)(TNFR-I)(p55)(CD120a antigen) [Source:UniProtKB/Swiss-Prot;Acc:P25118] manually curated
TNFRSF1B TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1B, CD120B, P75, P75 TNFR, TNF-ALPHAR2, TNF-R-II, TNF-R2, TNF-R75, TNFALPHA-R2, TNFBR, TNFR-1, TNFR2, TNFR80, TNFRII Tumor necrosis factor receptor superfamily member 1B Precursor (Tumor necrosis factor receptor 2)(TNF-R2)(Tumor necrosis factor receptor type II)(p75)(p80 TNF-alpha receptor)(CD120b antigen) [Source:UniProtKB/Swiss-Prot;Acc:P25119] manually curated
TNFRSF22 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 22, 2810028K06RIK, C130035G06RIK, MDCTRAILR2, SOBA, TNFRH2 Tumor necrosis factor receptor superfamily member 22 (Tumor necrosis factor receptor p60 homolog 2)(TNF receptor family member SOBa)(Decoy TRAIL receptor 2)(TNF receptor homolog 2) [Source:UniProtKB/Swiss-Prot;Acc:Q9ER62] manually curated
TNFRSF23 TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 23, MDCTRAILR1, MSOB, TNFRH1 Tumor necrosis factor receptor superfamily member 23 Precursor (Tumor necrosis factor receptor p60 homolog 1)(TNF receptor family member SOB)(Decoy TRAIL receptor 1)(TNF receptor homolog 1) [Source:UniProtKB/Swiss-Prot;Acc:Q9ER63] manually curated
TRADD TRADD, TNFRSF1A-ASSOCIATED VIA DEATH DOMAIN Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein)(TNFRSF1A-associated via death domain) [Source:UniProtKB/Swiss-Prot;Acc:Q3U0V2] manually curated
TRAIL TNFSF10, TUMOR NECROSIS FACTOR (LIGAND) SUPERFAMILY MEMBER 10, APO-2L, TRAIL Tumor necrosis factor ligand superfamily member 10 (TNF-related apoptosis-inducing ligand)(Protein TRAIL)(CD253 antigen) manually curated
TRP53 TP53, P53, TUMOR SUPPRESSOR P53, TRP53, CELLULAR TUMOR ANTIGEN P53 transformation related protein 53 Gene [Source:MGI (curated);Acc:Trp53-001] manually curated
XIAP X-LINKED INHIBITOR OF APOPTOSIS, 1110015C02RIK, AIPA, API3, BIRC4, IAP3, ILP-1 Baculoviral IAP repeat-containing protein 4 (EC 6.3.2.-)(E3 ubiquitin-protein ligase XIAP)(Inhibitor of apoptosis protein 3)(X-linked inhibitor of apoptosis protein)(X-linked IAP)(IAP homolog A)(MIAP-3)(MIAP3) [Source:UniProtKB/Swiss-Prot;Acc:Q60989] manually curated