ZAP70 (Equus caballus)
Description [+]
- Synonyms: ZAP70
- Species: Equus caballus
- Short gene description: Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2)(70 kDa zeta-associated protein)(Syk-related tyrosine kinase) [Source:UniProtKB/Swiss-Prot;Acc:P43403]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: ZAP70-E_caballus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | SH2 | 5 | 81 |
PFAM A | SH2 | 156 | 232 |
PFAM A | Pkinase | 331 | 586 |
PFAM A | Pkinase_Tyr | 331 | 586 |
Protein sequence [+]
ZAP70 | Equus caballus | 9796 | length:612
AHLPFFYGISRAEAEEAPGSWRGMADGLFLLRQWLRSLGGYVLSLVHNVRFQHFPIERQL
NGTYAIAGGKHCGPAELCEFYSRDPDGLPCNLRPCNRPSGLEPQPGVFDSLRDAMVRDYV
RQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHNSLSREEAERKLYAGSQTDGKF
LLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLI
YCLKEACPNNNASAGAGAAAPTLPAHPSTFTHPQKRIDTLNSDGYTPEPARLASPEKVRP
MPMDTSVYESPYSDPEELKDKKLFLKRENLLIADIELGCGNFGSVRQGVYRMRKKQIDVA
IKVLKHSTEKADKDEMMREAQIMHQLDNPYIVRLIGVCQAEALMLIMEMAGGGPLHKFLL
GKKEEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALG
ADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEAFSYGQKPYKKMKGPE
VMAFIEQGKRMECPPECPPEMYTLMSDCWIYKWEDRPDFVTVEQRMRAYYYSLASKVEGS
SGGEKGAEVTCP
NGTYAIAGGKHCGPAELCEFYSRDPDGLPCNLRPCNRPSGLEPQPGVFDSLRDAMVRDYV
RQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHNSLSREEAERKLYAGSQTDGKF
LLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLI
YCLKEACPNNNASAGAGAAAPTLPAHPSTFTHPQKRIDTLNSDGYTPEPARLASPEKVRP
MPMDTSVYESPYSDPEELKDKKLFLKRENLLIADIELGCGNFGSVRQGVYRMRKKQIDVA
IKVLKHSTEKADKDEMMREAQIMHQLDNPYIVRLIGVCQAEALMLIMEMAGGGPLHKFLL
GKKEEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALG
ADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEAFSYGQKPYKKMKGPE
VMAFIEQGKRMECPPECPPEMYTLMSDCWIYKWEDRPDFVTVEQRMRAYYYSLASKVEGS
SGGEKGAEVTCP
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0006955 | immune response | biological_proccess | IEA |
GO:0045582 | positive regulation of T cell differentiation | biological_proccess | IEA |
GO:0045059 | positive thymic T cell selection | biological_proccess | IEA |
GO:0006468 | protein amino acid phosphorylation | biological_proccess | IEA |
GO:0007242 | intracellular signaling cascade | biological_proccess | IEA |
GO:0046777 | protein amino acid autophosphorylation | biological_proccess | IEA |
GO:0050852 | T cell receptor signaling pathway | biological_proccess | IEA |
GO:0046641 | positive regulation of alpha-beta T cell proliferation | biological_proccess | IEA |
GO:0018108 | peptidyl-tyrosine phosphorylation | biological_proccess | IEA |
GO:0050850 | positive regulation of calcium-mediated signaling | biological_proccess | IEA |
GO:0046638 | positive regulation of alpha-beta T cell differentiation | biological_proccess | IEA |
GO:0045060 | negative thymic T cell selection | biological_proccess | IEA |
GO:0045061 | thymic T cell selection | biological_proccess | IEA |
GO:0043366 | beta selection | biological_proccess | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0005524 | ATP binding | mollecular_function | IEA |
GO:0004672 | protein kinase activity | mollecular_function | IEA |
GO:0004713 | protein tyrosine kinase activity | mollecular_function | IEA |
GO:0001784 | phosphotyrosine binding | mollecular_function | IEA |
GO:0042101 | T cell receptor complex | cell_component | IEA |
GO:0005829 | cytosol | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSECAG00000011012
- Expression info from Arrayexpress [?] : ENSECAG00000011012
- Protein expression from Protein Atlas: [?] ENSECAG00000011012
- Community gene edition from Wikigenes: [?] 100147296
- entrezgene: 100147296
Click on [?] for more information.