TRAF4 (Homo sapiens)
Description [+]
- Synonyms: TRAF4
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Hominidae; Homo sapiens
- Short gene description: TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1)(Malignant 62)(RING finger protein 83) [Source:UniProtKB/Swiss-Prot;Acc:Q9BUZ4]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: TRAF4-H_sapiens
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | zf-TRAF | 102 | 156 |
PFAM A | zf-TRAF | 157 | 210 |
PFAM A | zf-TRAF | 211 | 269 |
PFAM A | MATH | 314 | 464 |
Protein sequence [+]
TRAF4 | Homo sapiens | 9606 | length:470
MPGFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEGVFKCPEDQLP
LDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMK
LSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLL
AQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLK
DSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELE
ELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEG
THLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKP
GTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVELPRKILS
LDYAKIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMK
LSRRDLPAHLQHDCPKRRLKCEFCGCDFSGEAYESHEGMCPQESVYCENKCGARMMRRLL
AQHATSECPKRTQPCTYCTKEFVFDTIQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLK
DSCNTALVLCPFKDSGCKHRCPKLAMARHVEESVKPHLAMMCALVSRQRQELQELRRELE
ELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEG
THLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKP
GTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVELPRKILS
Structure links:
- Smartdomain prediction information: SM00504
- Smartdomain prediction information: SM00184
- Smartdomain prediction information: SM00061
- Prosite motif and domain information: PS00518
- Profile motif and domain profile information: PS50144
- Profile motif and domain profile information: PS50089
- Profile motif and domain profile information: PS50145
- Interpro domain information: Q9BUZ4
- PFAM domain and domain family information: Q9BUZ4
- Protein 3D structures from PDB: 2EOD
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
GO:0007165 | signal transduction | biological_proccess | TAS |
GO:0007275 | multicellular organismal development | biological_proccess | IEA |
GO:0016567 | protein ubiquitination | biological_proccess | IEA |
GO:0007585 | respiratory gaseous exchange | biological_proccess | IEA |
GO:0030323 | respiratory tube development | biological_proccess | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0008270 | zinc ion binding | mollecular_function | IEA |
GO:0003677 | DNA binding | mollecular_function | TAS |
GO:0046872 | metal ion binding | mollecular_function | IEA |
GO:0004842 | ubiquitin-protein ligase activity | mollecular_function | IEA |
GO:0005634 | nucleus | cell_component | TAS |
GO:0005737 | cytoplasm | cell_component | IEA |
GO:0000151 | ubiquitin ligase complex | cell_component | IEA |
Check GO Evidence Codes here
KEGG Pathways [+]
Information from other databases [+]
- Gene info from HGNC [?] :12034
- Gene related info from GeneCards [?] : TRAF4
- Ensembl genome browser [?] : ENSG00000076604
- Expression info from Arrayexpress [?] : ENSG00000076604
- Protein expression from Protein Atlas: [?] ENSG00000076604
- Community gene edition from Wikigenes: [?] 9618
- OMIM gene information: 602464
- OMIM disease information:
Click on [?] for more information.