CASP1 (Pongo pygmaeus)
Description [+]
- Synonyms: CASP1
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Primates;Hominidae; Pongo pygmaeus
- Short gene description: Caspase-1 Precursor (CASP-1)(EC 3.4.22.36)(Interleukin-1 beta convertase)(IL-1BC)(Interleukin-1 beta-converting enzyme)(IL-1 beta-converting enzyme)(ICE)(p45) [Contains Caspase-1 subunit p20;Caspase-1 subunit p10] [Source:UniProtKB/Swiss-Prot;Acc:P29466]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: CASP1-P_pygmaeus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | CARD | 3 | 90 |
PFAM A | Peptidase_C14 | 163 | 400 |
Protein sequence [+]
CASP1 | Pongo pygmaeus | 9600 | length:404
MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEETEKVKRENATVMDKTRALLDS
LIPKGARACEICITYICEEDSYLAETLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDN
PAMPTSSGSKGNVKLCSLKEAQKIWKEKPAEIYPIMDKSSRTRLALIICNEEFDSIPRRT
GAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELKAFAHRPEHKTSDSTFLVFMSHGIR
EGICGKKHSEQVPDVLQLNEIFKMLNTKNCPSLKDKPKVIIIQACRGDSHGVVWLKDSVG
VSRNISLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIMRLIQHMQEY
ACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH
LIPKGARACEICITYICEEDSYLAETLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDN
PAMPTSSGSKGNVKLCSLKEAQKIWKEKPAEIYPIMDKSSRTRLALIICNEEFDSIPRRT
GAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELKAFAHRPEHKTSDSTFLVFMSHGIR
EGICGKKHSEQVPDVLQLNEIFKMLNTKNCPSLKDKPKVIIIQACRGDSHGVVWLKDSVG
VSRNISLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIMRLIQHMQEY
ACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH
Structure links:
Evolution [+]
Explore tree at phylomeDB:   Click here.
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Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0006508 | proteolysis | biological_proccess | IEA |
GO:0042981 | regulation of apoptosis | biological_proccess | IEA |
GO:0006915 | apoptosis | biological_proccess | IEA |
GO:0006917 | induction of apoptosis | biological_proccess | IEA |
GO:0050718 | positive regulation of interleukin-1 beta secretion | biological_proccess | IEA |
GO:0008219 | cell death | biological_proccess | IEA |
GO:0001666 | response to hypoxia | biological_proccess | IEA |
GO:0016485 | protein processing | biological_proccess | IEA |
GO:0042221 | response to chemical stimulus | biological_proccess | IEA |
GO:0033198 | response to ATP | biological_proccess | IEA |
GO:0050715 | positive regulation of cytokine secretion | biological_proccess | IEA |
GO:0050717 | positive regulation of interleukin-1 alpha secretion | biological_proccess | IEA |
GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB cascade | biological_proccess | IEA |
GO:0005515 | protein binding | mollecular_function | IEA |
GO:0008234 | cysteine-type peptidase activity | mollecular_function | IEA |
GO:0008233 | peptidase activity | mollecular_function | IEA |
GO:0005622 | intracellular | cell_component | IEA |
GO:0005576 | extracellular region | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSPPYG00000003826
- Expression info from Arrayexpress [?] : ENSPPYG00000003826
- Protein expression from Protein Atlas: [?] ENSPPYG00000003826
Click on [?] for more information.