PRDX3 (Rattus norvegicus)
Description [+]
- Synonyms: PRDX3
- Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Rodentia; Rattus norvegicus
- Short gene description: Thioredoxin-dependent peroxide reductase, mitochondrial precursor (EC 1.11.1.15) (Peroxiredoxin-3) (PRX-3) (PRx III). [Source:UniProtKB/Swiss-Prot;Acc:Q9Z0V6]
- Family: Null
- Process:
- Pathways:
- Criteria: homology search
- Curator comment: Null
- WIKI: PRDX3-R_norvegicus
Structure & Sequence [+]
Pfam domains:
(Pfam is a large collection of protein families.)
Source | Domain Name | Start | End |
---|---|---|---|
PFAM A | Redoxin | 65 | 220 |
PFAM A | AhpC-TSA | 66 | 199 |
PFAM A | 1-cysPrx_C | 209 | 252 |
Protein sequence [+]
Prdx3 | Rattus norvegicus | 10116 | length:257
MAAAAGRLLWSSVARPASTIFRSISASTVLRPVASRRTCLTDMLWSACPQAKFAFSTSSS
FHTPAVTQHAPHFKGTAVVNGEFKELSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKA
NEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNITLLSDLTKQISRDYGVLLESA
GIALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQFVETHGEVCPANWTPESPT
IKPSPTASKEYFEKVHQ
FHTPAVTQHAPHFKGTAVVNGEFKELSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKA
NEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNITLLSDLTKQISRDYGVLLESA
GIALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQFVETHGEVCPANWTPESPT
IKPSPTASKEYFEKVHQ
Evolution [+]
Explore tree at phylomeDB:   Click here.
DeathBase uses Jalview, an external application that requires Java. Please, check that you have the latest version of Java
installed and that Java is enabled in your browser. When correctly installed your browser should display the following examples properly. You can download the latest version of Java at Java Download Site.
Gene Ontology [+]
GO id | Name | Ontology type | Evidence |
---|---|---|---|
GO:0001893 | maternal placenta development | biological_proccess | IEA |
GO:0006979 | response to oxidative stress | biological_proccess | IEA |
GO:0030099 | myeloid cell differentiation | biological_proccess | IEA |
GO:0032496 | response to lipopolysaccharide | biological_proccess | IEA |
GO:0043524 | negative regulation of neuron apoptosis | biological_proccess | IMP |
GO:0045454 | cell redox homeostasis | biological_proccess | IEA |
GO:0055114 | oxidation reduction | biological_proccess | IEA |
GO:0042542 | response to hydrogen peroxide | biological_proccess | IEA |
GO:0008284 | positive regulation of cell proliferation | biological_proccess | IEA |
GO:0051092 | positive regulation of NF-kappaB transcription factor activity | biological_proccess | IEA |
GO:0007005 | mitochondrion organization | biological_proccess | IEA |
GO:0043066 | negative regulation of apoptosis | biological_proccess | IEA |
GO:0051881 | regulation of mitochondrial membrane potential | biological_proccess | IEA |
GO:0034614 | cellular response to reactive oxygen species | biological_proccess | IEA |
GO:0042744 | hydrogen peroxide catabolic process | biological_proccess | IEA |
GO:0033673 | negative regulation of kinase activity | biological_proccess | IEA |
GO:0016491 | oxidoreductase activity | mollecular_function | IEA |
GO:0042802 | identical protein binding | mollecular_function | IEA |
GO:0051920 | peroxiredoxin activity | mollecular_function | IEA |
GO:0016209 | antioxidant activity | mollecular_function | IEA |
GO:0019901 | protein kinase binding | mollecular_function | IEA |
GO:0008022 | protein C-terminus binding | mollecular_function | IEA |
GO:0043027 | caspase inhibitor activity | mollecular_function | IEA |
GO:0005739 | mitochondrion | cell_component | IEA |
GO:0005737 | cytoplasm | cell_component | IEA |
GO:0005769 | early endosome | cell_component | IEA |
GO:0008385 | IkappaB kinase complex | cell_component | IEA |
Check GO Evidence Codes here
Information from other databases [+]
- Ensembl genome browser [?] : ENSRNOG00000010958
- Expression info from Arrayexpress [?] : ENSRNOG00000010958
- Protein expression from Protein Atlas: [?] ENSRNOG00000010958
Click on [?] for more information.