FAS (Rattus norvegicus)

Description [+]

Synonyms: FAS
Species: Metazoa;Bilateria;Deuterostoma;Chordata;Vertebrata;Mammalia;Rodentia; Rattus norvegicus
Short gene description: Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen). [Source:UniProtKB/Swiss-Prot;Acc:Q63199]
Family: Null
Process:
Pathways:
Criteria: homology search
Curator comment: Null
WIKI: FAS-R_norvegicus

Structure & Sequence [+]

Pfam domains: (Pfam is a large collection of protein families.)

Source	Domain Name	Start	End
PFAM A	TNFR_c6	71	113
PFAM A	Death	210	293

Protein sequence [+]

Structure links:

Smartdomain prediction information: SM00208
Smartdomain prediction information: SM00005
Prosite motif and domain information: PS00652
Interpro domain information: Q63199
PFAM domain and domain family information: Q63199

Evolution [+]

Gene Ontology [+]

GO id	Name	Ontology type	Evidence
GO:0001666	response to hypoxia	biological_proccess	IEP
GO:0006915	apoptosis	biological_proccess	IEA
GO:0006955	immune response	biological_proccess	IEA
GO:0007165	signal transduction	biological_proccess	IEA
GO:0007283	spermatogenesis	biological_proccess	IEP
GO:0007568	aging	biological_proccess	IEP
GO:0008625	induction of apoptosis via death domain receptors	biological_proccess	IEP
GO:0009636	response to toxin	biological_proccess	IEP
GO:0010035	response to inorganic substance	biological_proccess	IEP
GO:0032496	response to lipopolysaccharide	biological_proccess	IEP
GO:0034097	response to cytokine stimulus	biological_proccess	IEP
GO:0042493	response to drug	biological_proccess	IEP
GO:0042698	ovulation cycle	biological_proccess	IEP
GO:0043434	response to peptide hormone stimulus	biological_proccess	IEP
GO:0043627	response to estrogen stimulus	biological_proccess	IEP
GO:0002377	immunoglobulin production	biological_proccess	IEA
GO:0003014	renal system process	biological_proccess	IEA
GO:0006924	activation-induced cell death of T cells	biological_proccess	IEA
GO:0006925	inflammatory cell apoptosis	biological_proccess	IEA
GO:0006927	transformed cell apoptosis	biological_proccess	IEA
GO:0010467	gene expression	biological_proccess	IEA
GO:0019724	B cell mediated immunity	biological_proccess	IEA
GO:0043066	negative regulation of apoptosis	biological_proccess	IEA
GO:0045060	negative thymic T cell selection	biological_proccess	IEA
GO:0045619	regulation of lymphocyte differentiation	biological_proccess	IEA
GO:0045637	regulation of myeloid cell differentiation	biological_proccess	IEA
GO:0048536	spleen development	biological_proccess	IEA
GO:0050869	negative regulation of B cell activation	biological_proccess	IEA
GO:0051260	protein homooligomerization	biological_proccess	IEA
GO:0051384	response to glucocorticoid stimulus	biological_proccess	IEA
GO:0051789	response to protein stimulus	biological_proccess	IEA
GO:0009636	response to toxin	biological_proccess	IEA
GO:0043065	positive regulation of apoptosis	biological_proccess	IEA
GO:0043029	T cell homeostasis	biological_proccess	IEA
GO:0008624	induction of apoptosis by extracellular signals	biological_proccess	IEA
GO:0008625	induction of apoptosis via death domain receptors	biological_proccess	IEA
GO:0004888	transmembrane receptor activity	mollecular_function	IEA
GO:0005031	tumor necrosis factor receptor activity	mollecular_function	TAS
GO:0005515	protein binding	mollecular_function	IPI
GO:0004872	receptor activity	mollecular_function	IEA
GO:0005901	caveola	cell_component	IEP
GO:0016020	membrane	cell_component	IEA
GO:0048471	perinuclear region of cytoplasm	cell_component	IDA
GO:0005576	extracellular region	cell_component	IEA
GO:0009897	external side of plasma membrane	cell_component	IEA
GO:0016021	integral to membrane	cell_component	IEA
GO:0009986	cell surface	cell_component	IEA

Check GO Evidence Codes here

KEGG Pathways [+]

Information from other databases [+]

Gene related links:

Ensembl genome browser [?] : ENSRNOG00000019142
Expression info from Arrayexpress [?] : ENSRNOG00000019142
Protein expression from Protein Atlas: [?] ENSRNOG00000019142

Protein related links:

Uniprot protein info: Q63199
PIR protein info: Q63199
Protein interactions from IntAct: Q63199

Other links

entrezgene: 246097
refseq_dna: NM_139194
refseq_peptide: NP_631933

Click on [?] for more information.