Your are not logged in. Log in.

CED-9   (Caenorhabditis elegans)

Description [+]
  • Synonyms: CED-9
  • Species: Metazoa;Bilateria;Ecdysozoa;Nematoda; Caenorhabditis elegans
  • Short gene description: ced-9 encodes the sole C. elegans homolog of the mammalian cell-death inhibitor Bcl-2. during development, CED-9 activity is essential for preventing cells from undergoing programmed cell death and CED-9 functions by binding and repressing the activity of CED-4, a protein similar to human APAF-1 that positively regulates CED-3 caspase activity. CED-9 localizes to mitochondria. [Source: WormBase]
  • Family: Bcl-2 family : multidomain Bcl-2
  • Process: apoptosis,
  • Pathways:
  • Criteria: manually curated
  • Curator comment:
  • Human ortholog(s): BCL2L2
  • WIKI: CED-9-C_elegans
References [+]
Structure & Sequence [+]
Evolution [+]
Gene Ontology [+]
Information from other databases [+]